Holddown arm release mechanism used on Saturn vehicles

With the development of the Saturn launch vehicle, it became mandatory to develop a system for restraining the vehicle until after all checks and engine thrust buildup were completed. The basic Saturn I holddown arm constrains the vehicle by clamping it between a fixed support and a movable jaw. The jaw is on a link pinned to rotate sufficiently to release the vehicle. There are three links in the jaw (restraining) system arranged so that with a small force provided by a pneumatic separator mechanism, the large loads of the vehicle can be restrained. Design details discussed are the link system, the separator, adjustments, and the energy absorber. The function of preloading is discussed. The secondary release system is described. Finally, the design differences between the Saturn I and the Saturn V arm are described

Resonance tube igniter

Reasonance induced in stoichiometric mixtures of gaseous hydrogen-oxygen produces temperatures /over 1100 deg F/ high enough to cause ignition. Resonance tube phenomenon occurs when high pressure gas is forced through sonic or supersonic nozzle into short cavity. Various applications for the phenomenon are discussed

Assessing the Effect of Photodynamic Therapy on Peripheral Nerve and Cancer Cells Using a Thin Tissue Engineered Collagen Culture Model

Abstract not available

Lorentz Violation and Synchrotron Radiation

We consider the radiation emitted by an ultrarelativistic charged particle moving in a magnetic field, in the presence of an additional Lorentz-violating interaction. In contrast with prior work, we treat a form of Lorentz violation that is represented by a renormalizable operator. Neglecting the radiative reaction force, the particle's trajectory can be determined exactly. The resulting orbit is generally noncircular and does not lie in the place perpendicular to the magnetic field. We do not consider any Lorentz violation in the electromagnetic sector, so the radiation from the accelerated charge can be determined by standard means, and the radiation spectrum will exhibit a Lorentz-violating directional dependence. Using data on emission from the Crab nebula, we can set a bound on a particular combination of Lorentz-violating coefficients at the $6\times10^{-20}$ level.Comment: 14 page

The Renormalization Group Limit Cycle for the 1/r^2 Potential

Previous work has shown that if an attractive 1/r^2 potential is regularized at short distances by a spherical square-well potential, renormalization allows multiple solutions for the depth of the square well. The depth can be chosen to be a continuous function of the short-distance cutoff R, but it can also be a log-periodic function of R with finite discontinuities, corresponding to a renormalization group (RG) limit cycle. We consider the regularization with a delta-shell potential. In this case, the coupling constant is uniquely determined to be a log-periodic function of R with infinite discontinuities, and an RG limit cycle is unavoidable. In general, a regularization with an RG limit cycle is selected as the correct renormalization of the 1/r^2 potential by the conditions that the cutoff radius R can be made arbitrarily small and that physical observables are reproduced accurately at all energies much less than hbar^2/mR^2.Comment: 11 pages, 4 figure

Differences in sensitivity to mTHPC-mediated photodynamic therapy of neurons, glial cells and MCF7 cells in a 3-dimensional cell culture model

The effect of photodynamic therapy (PDT) on the cells of the nervous system is an important consideration in the treatment of tumours that are located within or adjacent to the brain, spinal cord and peripheral nerves. Previous studies have reported the sparing of nerves during PDT using meta-tetrahydroxyphenylchlorin (mTHPC, Foscan®) in patients and in animal models. The aim of this study was to investigate the effects of mTHPC on key nervous system cells using a 3-dimensional cell culture system for the accurate detection of differences in sensitivity

Intracellular localisation of mTHPC and effect of photodynamic therapy in cells of the mammalian peripheral nervous system

Fewer nerve-related side effects have been noted after treating head and neck cancer with photodynamic therapy (PDT) compared to conventional cancer therapy. Our aim is to investigate the biological basis for any such nerve-sparing effect. In this study the intracellular localisation and effect on cell viability of the photosensitiser meta-tetrahydroxylphenylchlorin (mTHPC) was investigated in cell culture models using peripheral nerve cells. Primary cells from adult rat dorsal root ganglia (containing both neurons and glia) were used in these experiments. Localisation of mTHPC was detected using fluorescence and confocal microscopy. Levels of mTHPC fluorescence were quantified using digital image analysis. Immunocytochemistry with anti-?-III-tubulin and anti-S100 was used to distinguish neuronal and glial cell populations respectively. A cell-death assay using propidium iodide was used to evaluate neural cell susceptibility to PDT following incubation with mTHPC. The results showed that mTHPC was localised in cytoplasmic regions of neurons and glia, but was not detected in neuronal axons. Necrotic cell death was detected after PDT in these neural cell types. These results suggest that the cells of the peripheral nervous system are susceptible to PDT-mediated necrosis, but that the sparing of nerves observed during clinical PDT may be related to the heterogeneous distribution of mTHPC within neurons

Silicon abundance from RESIK solar flare observations

The RESIK instrument on the CORONAS-F spacecraft obtained solar flare and active region X-ray spectra in four channels covering the wavelength range 3.8 -- 6.1 \AA in its operational period between 2001 and 2003. Several highly ionized silicon lines were observed within the range of the long-wavelength channel (5.00 -- 6.05 \AA). The fluxes of the \sixiv Ly-$\beta$ line (5.217 \AA) and the \sixiii $1s^2 - 1s3p$ line (5.688 \AA) during 21 flares with optimized pulse-height analyzer settings on RESIK have been analyzed to obtain the silicon abundance relative to hydrogen in flare plasmas. As in previous work, the emitting plasma for each spectrum is assumed to be characterized by a single temperature and emission measure given by the ratio of emission in the two channels of GOES. The silicon abundance is determined to be $A({\rm Si}) = 7.93 \pm .21$ (\sixiv) and $7.89 \pm .13$ (\sixiii) on a logarithmic scale with H = 12. These values, which vary by only very small amounts from flare to flare and times within flares, are $2.6 \pm 1.3$ and $2.4 \pm 0.7$ times the photospheric abundance, and are about a factor of three higher than RESIK measurements during a period of very low activity. There is a suggestion that the Si/S abundance ratio increases from active regions to flares.Comment: To be published, Solar Physic