484 research outputs found
Mechanisms of Psychological Distress following War in the Former Yugoslavia: The Role of Interpersonal Sensitivity
This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.This study was funded by a grant from the European Commission, contract number INCO-CT-2004-509176. AN was supported by a Clinical Early Career Research Fellowship (113295) and a Project Grant (104288
Workflow and Performance Under Computer Mediated Interruptions
Technologically enhanced computer mediated communication (CMC) environments create a trade-off between eliminating delays and increasing performance. In such environments, incoming interruptions can break the “flow” of work and deteriorate performance. In this regard, we describe a mechanism that explains why particular types of information are attended to, and how such interruptions interrupt work flow creating deterioration in performance. Specifically, this study investigates to specific facets of interruptions, the influence of task presentation format and interruption relevance on performance. Results showed significant performance differences related to different presentation format and interruption relevancy. Furthermore, flow had a significant effect on work performance. Future research should future propose more comprehensive taxonomies of both interruption in task characteristics, and examine the effects of such interruptions in systematic ways and in different contexts
The effect of spin orbit interaction on the physical properties of LaTSi3 (T = Ir, Pd, and Rh): First-principles calculations
This is the final version of the article. Available from AIP Publishing via the DOI in this record.We have presented the structural, elastic, electronic, phononic, and electron-phonon interaction properties of the La-based noncentrosymmetric superconductors, such as LaIrSi3, LaRhSi3, and LaPdSi3, by using the generalized gradient approximation of the density functional theory. The calculated elastic constants reveal the mechanical stability of all the studied compounds in their noncentrosymmetric structure, while the lack of inversion symmetry gives rise to lift the degeneracy of their electronic bands, except in the Γ-Z and X-P directions. The calculated Eliashberg spectral function shows that all phonon branches of these materials couple considerably with electrons, and thus, all of them make contribution to the average electron-phonon coupling parameter λ. Using the calculated values of λ and the logarithmically averaged phonon frequency ωln, the superconducting critical temperature Tc values for LaIrSi3, LaRhSi3, and LaPdSi3 are estimated to be 0.89, 2.56, and 2.40 K, respectively, which accord very well with their corresponding experimental values of 0.77, 2.16, and 2.60 K.This work was supported by the Scientific and Technical Research Council of Turkey (TÜBİTAK) (Project No. MFAG-115F135)
P2X7 receptors induce degranulation in human mast cells.
Mast cells play important roles in host defence against pathogens, as well as being a key effector cell in diseases with an allergic basis such as asthma and an increasing list of other chronic inflammatory conditions. Mast cells initiate immune responses through the release of newly synthesised eicosanoids and the secretion of pre-formed mediators such as histamine which they store in specialised granules. Calcium plays a key role in regulating both the synthesis and secretion of mast-cell-derived mediators, with influx across the membrane, in particular, being necessary for degranulation. This raises the possibility that calcium influx through P2X receptors may lead to antigen-independent secretion of histamine and other granule-derived mediators from human mast cells. Here we show that activation of P2X7 receptors with both ATP and BzATP induces robust calcium rises in human mast cells and triggers their degranulation; both effects are blocked by the P2X7 antagonist AZ11645373, or the removal of calcium from the extracellular medium. Activation of P2X1 receptors with αβmeATP also induces calcium influx in human mast cells, which is significantly reduced by both PPADS and NF 449. P2X1 receptor activation, however, does not trigger degranulation. The results indicate that P2X7 receptors may play a significant role in contributing to the unwanted activation of mast cells in chronic inflammatory conditions where extracellular ATP levels are elevated
Comparison of Nutrition Status and Knowledge Level of Sports Trainers and Individuals Attended with Nine-Round Fitness Sports
The aim of this study was to determine and evaluate the nutritional knowledge levels and nutritional status of the sports trainers and individuals doing nine-round fitness sports, and compare the relationship between two groups. One hundred individuals doing sports and 10 trainers were included in the study. A questionnaire about general demographic information, anthropometric measurements, nutritional habits and sporting status were applied to the participants. In addition, 1-day retrospective food consumption record was taken to evaluate the intake levels of macro and micronutrients, and The Basic Nutrition Knowledge Level for Adults (YETBID) Scale was applied to measure the nutritional knowledge of the participants. The mean energy (kcal), protein (g), fat (g) and carbohydrate (g) intakes were found to be 1930±832,6, 117,8±61,3, 88±34,5, 159±111,1 for trainers and 1465±533, 81,8±33,9, 66,6±26,4, 128±76,9 for individuals doing sports, respectively. A significant difference was found between two groups in terms of energy intakes (p=0,042) whereas, no significant difference was found between the levels of macro nutrient intakes between trainers and individuals doing sports (p>0.05). According to the YETBID scores, it was found that the total score of individuals doing sports was significantly higher than trainers’ (p=0.037). It was concluded that the level of nutritional knowledge of sports trainers and individuals doing sports did not affect the nutritional status. Furthermore, dietitians should be present at sport centers and nutrition trainings should be arranged in order to prevent improper nutrition practices
Mental fortitude training: An evidence-based approach to developing psychological resilience for sustained success
Drawing on the body of knowledge in this area, this article presents an evidence-based approach to developing psychological resilience for sustained success. To this end, the narrative is divided into three main sections. The first section describes the construct of psychological resilience and explains what it is. The second section outlines and discusses a mental fortitude training™ program for aspiring performers. The third section provides recommendations for practitioners implementing this program. It is hoped that this article will facilitate a holistic and systematic approach to developing resilience for sustained success
Clinical characteristics and positive airway pressure adherence among elderly European sleep apnoea patients from the ESADA cohort
Background The prevalence of obstructive sleep apnoea (OSA) is growing as the population is ageing. However, data on the clinical characteristics of elderly patients with OSA and their adherence to positive airway pressure (PAP) treatment are scarce.Methods Data from 23 418 30-79-year-old OSA patients prospectively collected into the ESADA database during 2007-2019 were analysed. Information on PAP use (h.day(-1)) in association with a first follow-up visit was available for 6547 patients. The data was analysed according to 10-year age groups.Results The oldest age group was less obese, less sleepy and had a lower apnoea-hypopnoea index (AHI) compared with middle-aged patients. The insomnia phenotype of OSA was more prevalent in the oldest age group than in the middle-aged group (36%, 95% CI 34-38 versus 26%, 95% CI 24-27, p<0.001). The 70-79-year-old group adhered to PAP therapy equally well as the younger age groups with a mean PAP use of 5.59 h.day(-1) (95% CI 5.44-5.75). PAP adherence did not differ between clinical phenotypes based on subjective daytime sleepiness and sleep complaints suggestive of insomnia in the oldest age group. A higher score on the Clinical Global Impression Severity (CGI-S) scale predicted poorer PAP adherence.Conclusion The elderly patient group was less obese, less sleepy, had more insomnia symptoms and less severe OSA, but were rated to be more ill compared with the middle-aged patients. Elderly patients with OSA adhered to PAP therapy equally well as middle-aged patients. Low global functioning (measured by CGI-S) in the elderly patient predicted poorer PAP adherence
Psychological distress among Bam earthquake survivors in Iran: a population-based study
BACKGROUND: An earthquake measuring 6.3 on the Richter scale struck the city of Bam in Iran on the 26th of December 2003 at 5.26 A.M. It was devastating, and left over 40,000 dead and around 30,000 injured. The profound tragedy of thousands killed has caused emotional and psychological trauma for tens of thousands of people who have survived. A study was carried out to assess psychological distress among Bam earthquake survivors and factors associated with severe mental health in those who survived the tragedy. METHODS: This was a population-based study measuring psychological distress among the survivors of Bam earthquake in Iran. Using a multi-stage stratified sampling method a random sample of individuals aged 15 years and over living in Bam were interviewed. Psychological distress was measured using the 12-item General Health Questionnaire (GHQ-12). RESULTS: In all 916 survivors were interviewed. The mean age of the respondents was 32.9 years (SD = 12.4), mostly were males (53%), married (66%) and had secondary school education (50%). Forty-one percent reported they lost 3 to 5 members of their family in the earthquake. In addition the findings showed that 58% of the respondents suffered from severe mental health as measured by the GHQ-12 and this was three times higher than reported psychological distress among the general population. There were significant differences between sub-groups of the study sample with regard to their psychological distress. The results of the logistic regression analysis also indicated that female gender; lower education, unemployment, and loss of family members were associated with severe psychological distress among earthquake victims. CONCLUSION: The study findings indicated that the amount of psychological distress among earthquake survivors was high and there is an urgent need to deliver mental health care to disaster victims in local medical settings and to reduce negative health impacts of the earthquake adequate psychological counseling is needed for those who survived the tragedy
Worse patient- physician relationship is associated with more fear of cancer recurrence (Deimos Study): A study of the palliative care working committee of the Turkish Oncology Group (TOG)
44th Congress of the European-Society-for-Medical-Oncology (ESMO) -- SEP 27-OCT 01, 2019 -- Barcelona, SPAIN[Anstract Not Available]European Soc Med Oncol,Japanese Soc Med Onco
Determination of horizon size in state-based peridynamics
Peridynamics is based on integro-differential equations and has a length scale parameter called horizon which gives peridynamics a non-local character. Currently, there are three main peridynamic formulations available in the literature including bond-based peridynamics, ordinary state-based peridynamics and non-ordinary state-based peridynamics. In this study, the optimum horizon size is determined for ordinary state-based peridynamics and non-ordinary state-based peridynamics formulations by using uniform and non-uniform discretisation under dynamic and static conditions. It is shown that the horizon sizes selected as optimum sizes for uniform discretisation can also be used for non-uniform discretisation without introducing significant error to the system. Moreover, a smaller horizon size can be selected for non-ordinary state-based formulation which can yield significant computational advantage. It is also shown that same horizon size can be used for both static and dynamic problems
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