On the Non-Gaussianity Observed in the COBE-DMR Sky Maps

In this paper we pursue the origin of the non-Gaussianity determined by a bispectrum analysis of the COBE-DMR 4-year sky maps. The robustness of the statistic is demonstrated by the rebinning of the data into 12 coordinate systems. By computing the bispectrum statistic as a function of various data partitions - by channel, frequency, and time interval, we show that the observed non-Gaussian signal is driven by the 53 GHz data. This frequency dependence strongly rejects the hypothesis that the signal is cosmological in origin. A jack-knife analysis of the coadded 53 and 90 GHz sky maps reveals those sky pixels to which the bispectrum statistic is particularly sensitive. We find that by removing data from the 53 GHz sky maps for periods of time during which a known systematic effect perturbs the 31 GHz channels, the amplitudes of the bispectrum coefficients become completely consistent with that expected for a Gaussian sky. We conclude that the non-Gaussian signal detected by the normalised bispectrum statistic in the publicly available DMR sky maps is due to a systematic artifact. The impact of removing the affected data on estimates of the normalisation of simple models of cosmological anisotropy is negligible.Comment: 14 pages, plus 8 Postscript and 3 GIF figures. LaTeX2e document using AASTeX v5.0 macros. Revised version accepted for publication in the Astrophysical Journal: small changes to the text, minor modifications to figures 1 and

Formality and informality in the summative assessment of motor vehicle apprentices: a case study

This article explores the interaction of formal and informal attributes of competence‐based assessment. Specifically, it presents evidence from a small qualitative case study of summative assessment practices for competence‐based qualifications within apprenticeships in the motor industry in England. The data are analysed through applying an adaptation of a framework for exploring the interplay of formality and informality in learning. This analysis reveals informal mentoring as a significant element which influences not only the process of assessment, but also its outcomes. We offer different possible interpretations of the data and their analysis, and conclude that, whichever interpretation is adopted, there appears to be a need for greater capacity‐building for assessors at a local level. This could acknowledge a more holistic role for assessors; recognise the importance of assessors’ informal practices in the formal retention and achievement of apprentices; and enhance awareness of inequalities that may be reinforced by both informal and formal attributes of assessment practices

Towards Locating the Brightest Microlensing Events on the Sky

It is estimated that a star brighter than visual magnitude 17 is undergoing a detectable gravitational microlensing event, somewhere on the sky, at any given time. It is assumed that both lenses and sources are normal stars drawn from a standard Bahcall-Soneira model of our Galaxy. Furthermore, over the time scale of a year, a star 15th magnitude or brighter should undergo a detectable gravitational lens amplification. Detecting and studying the microlensing event rate among the brightest 10$^8$ stars could yield a better understanding of Galactic stellar and dark matter distributions. Diligent tracking of bright microlensing events with even small telescopes might detect planets orbiting these stellar lenses.Comment: 19 pages, 4 figures, accepted by Ap

High-Resolution Continuum Imaging at 1.3 and 0.7 cm of the W3 IRS 5 Region

High-resolution images of the hypercompact HII regions (HCHII) in W3 IRS 5 taken with the Very Large Array (VLA) at 1.3 and 0.7 cm are presented. Four HCHII regions were detected with sufficient signal-to-noise ratios to allow the determination of relevant parameters such as source position, size and flux density. The sources are slightly extended in our ~0.2 arcsecond beams; the deconvolved radii are less than 240 AU. A comparison of our data with VLA images taken at epoch 1989.1 shows proper motions for sources IRS 5a and IRS 5f. Between 1989.1 and 2002.5, we find a proper motion of 210 mas at a position angle of 12 deg for IRS 5f and a proper motion of 190 mas at a position angle of 50 deg for IRS 5a. At the assumed distance to W3 IRS 5, 1.83 +/- 0.14 kpc, these offsets translate to proper motions of ~135 km/s and ~122 km/s$ respectively. These sources are either shock ionized gas in an outflow or ionized gas ejected from high mass stars. We find no change in the positions of IRS 5d1/d2 and IRS 5b; and we show through a comparison with archival NICMOS 2.2 micron images that these two radio sources coincide with the infrared double constituting W3 IRS 5. These sources contain B or perhaps O stars. The flux densities of the four sources have changed compared to the epoch 1989.1 results. In our epoch 2002.5 data, none of the spectral indicies obtained from flux densities at 1.3 and 0.7 cm are consistent with optically thin free-free emission; IRS 5d1/d2 shows the largest increase in flux density from 1.3 cm to 0.7 cm. This may be an indication of free-free optical depth within an ionized wind, a photoevaporating disk, or an accretion flow. It is less likely that this increase is caused by dust emission at 0.7 cm.Comment: 13 pages, 3 figures To be published in The Astrophysical Journa

Interpreting ambiguous ‘trace’ results in Schistosoma mansoni CCA Tests: Estimating sensitivity and specificity of ambiguous results with no gold standard

Background The development of new diagnostics is an important tool in the fight against disease. Latent Class Analysis (LCA) is used to estimate the sensitivity and specificity of tests in the absence of a gold standard. The main field diagnostic for Schistosoma mansoni infection, Kato-Katz (KK), is not very sensitive at low infection intensities. A point-of-care circulating cathodic antigen (CCA) test has been shown to be more sensitive than KK. However, CCA can return an ambiguous ‘trace’ result between ‘positive’ and ‘negative’, and much debate has focused on interpretation of traces results. Methodology/Principle findings We show how LCA can be extended to include ambiguous trace results and analyse S. mansoni studies from both Côte d’Ivoire (CdI) and Uganda. We compare the diagnostic performance of KK and CCA and the observed results by each test to the estimated infection prevalence in the population. Prevalence by KK was higher in CdI (13.4%) than in Uganda (6.1%), but prevalence by CCA was similar between countries, both when trace was assumed to be negative (CCAtn: 11.7% in CdI and 9.7% in Uganda) and positive (CCAtp: 20.1% in CdI and 22.5% in Uganda). The estimated sensitivity of CCA was more consistent between countries than the estimated sensitivity of KK, and estimated infection prevalence did not significantly differ between CdI (20.5%) and Uganda (19.1%). The prevalence by CCA with trace as positive did not differ significantly from estimates of infection prevalence in either country, whereas both KK and CCA with trace as negative significantly underestimated infection prevalence in both countries. Conclusions Incorporation of ambiguous results into an LCA enables the effect of different treatment thresholds to be directly assessed and is applicable in many fields. Our results showed that CCA with trace as positive most accurately estimated infection prevalence

Streaming Algorithm for Euler Characteristic Curves of Multidimensional Images

We present an efficient algorithm to compute Euler characteristic curves of gray scale images of arbitrary dimension. In various applications the Euler characteristic curve is used as a descriptor of an image. Our algorithm is the first streaming algorithm for Euler characteristic curves. The usage of streaming removes the necessity to store the entire image in RAM. Experiments show that our implementation handles terabyte scale images on commodity hardware. Due to lock-free parallelism, it scales well with the number of processor cores. Our software---CHUNKYEuler---is available as open source on Bitbucket. Additionally, we put the concept of the Euler characteristic curve in the wider context of computational topology. In particular, we explain the connection with persistence diagrams

Energy advisors at work: charity work practices to support people in fuel poverty

We present an ethnographic study of energy advisors working for a charity that provides support, particularly to people in fuel poverty. Our fieldwork comprises detailed observations that reveal the collaborative, interactional work of energy advisors and clients during home visits, supplemented with interviews and a participatory design workshop with advisors. We identify opportunities for Ubicomp technologies that focus on supporting the work of the advisor, including complementing the collaborative advice giving in home visits, providing help remotely, and producing evidence in support of accounts of practices and building conditions useful for interactions with landlords, authorities and other third parties. We highlight six specific design challenges that relate the domestic fuel poverty setting to the wider Ubicomp literature. Our work echoes a shift in attention from energy use and the individual consumer, specifically to matters of advice work practices and the domestic fuel poverty setting, and to the discourse around inclusive Ubicomp technologies

Laminar-turbulent boundary-layer transition over a rough rotating disk

Boundary-layer transition over a disk spinning under water is investigated. Transitional Reynolds numbers, Re-c, and associated boundary-layer velocity profiles are determined from flow-visualizations and hot-film measurements, respectively. The value of Re-c and the velocity profiles are studied as a function of the disk's surface roughness. It is found that transition over rough disks occurs in a similar fashion to that over smooth disks, i.e., abruptly and axisymmetrically at well-defined radii. Wall roughness has little effect on Re-c until a threshold relative roughness is reached. Above the threshold Re-c decreases sharply. The decrease is consistent with the drop one expects for our flow for the absolute instability discovered by Lingwood [J. Fluid Mech. 299, 17 (1995); 314, 373 (1996); 331, 405 (1997)]. This indicates that the Lingwood absolute instability may continue to play a major role in the transition process even for large relative roughness. (C) 2003 American Institute of Physics

Study and implementation of urogenital schistosomiasis elimination in Zanzibar (Unguja and Pemba islands) using an integrated multidisciplinary approach

ABSTRACT: BACKGROUND: Schistosomiasis is a parasitic infection that continues to be a major public health problem in many developing countries being responsible for an estimated burden of at least 1.4 million disability-adjusted life years (DALYs) in Africa alone. However, morbidity due to schistosomiasis has been greatly reduced in some parts of the world, including Zanzibar. The Zanzibar government is now committed to eliminate urogenital schistosomiasis. Over the next 3--5 years, the whole at-risk population will be administered praziquantel (40 mg/kg) biannually. Additionally, snail control and behaviour change interventions will be implemented in selected communities and the impact measured in a randomized intervention trial. METHODS: In this 5-year research study, on both Unguja and Pemba islands, urogenital schistosomiasis will be assessed in 45 communities with urine filtration and reagent strips in 4,500 schoolchildren aged 9--12 years annually, and in 4,500 first-year schoolchildren and 2,250 adults in years 1 and 5. Additionally, from first-year schoolchildren, a finger-prick blood sample will be collected and examined for Schistosoma haematobium infection biomarkers. Changes in prevalence and infection intensity will be assessed annually. Among the 45 communities, 15 were randomized for biannual snail control with niclosamide, in concordance with preventive chemotherapy campaigns. The reduction of Bulinus globosus snail populations and S. haematobium-infected snails will be investigated. In 15 other communities, interventions triggering behaviour change have been designed and will be implemented in collaboration with the community. A change in knowledge, attitudes and practices will be assessed annually through focus group discussions and in-depth interviews with schoolchildren, teachers, parents and community leaders. In all 45 communities, changes in the health system, water and sanitation infrastructure will be annually tracked by standardized questionnaire-interviews with community leaders. Additional issues potentially impacting on study outcomes and all incurring costs will be monitored and recorded. DISCUSSION: Elimination of schistosomiasis has become a priority on the agenda of the Zanzibar government and the international community. Our study will contribute to identifying what, in addition to preventive chemotherapy, needs to be done to prevent, control, and ultimately eliminate schistosomiasis, and to draw lessons for current and future schistosomiasis elimination programmes in Africa and elsewhere.Trial registrationISRCTN4883768