Molecularly imprinted polymers for the determination of organophosphorus pesticides in complex samples

International audienceOrganophosphorus compounds constitute an important class of pesticides whose the toxicity of which arises from the inhibition of the acetylcholinesterase enzyme. They exhibit a wide range of physico-chemical properties, thus rendering their determination in complex oil samples particularly difficult. To facilitate their analysis at the trace level in various samples (environmental waters, soils, vegetables…), molecularly imprinted polymers (MIPs) that are synthetic polymers possessing specific cavities designed for a target molecule have been prepared. Often called synthetic antibodies, MIPs can replace antibodies in different application fields. Indeed, as immunosorbents, MIPs can be used as selective sorbents for the solid phase extraction of target analytes from complex matrices or as recognition elements in sensors. Their synthesis, characterization and use as selective sorbent for the selective recognition of organophosphorus pesticides have been already largely described and are summarized in this review

L'échinococcose alvéolaire : où la maladie sévit-elle ?

National audienc

Selective solid-phase extraction of organophosphorus pesticides and their oxon-derivatives from water samples using molecularly imprinted polymer followed by high-performance liquid chromatography with UV detection

A molecularly imprinted polymer was synthesized and characterized to be used as 27 solid-phase extraction sorbent for simultaneous chlorpyrifos and diazinon and their 28 oxon derivatives. Several imprinted polymers were prepared and evaluated in a 29 retention study of these analytes compared with a non-printed polymer. Several 30 parameters affecting the extraction of imprinted polymer such as washing solvent, 31 composition and volume of the eluting solvent and sample volume, were also 32 investigated. Under the optimum conditions, the developed method provided 33 satisfactory limits of detection ranging between 0.07 μg L−1 to 0.12 μg L−1 and the 34 material showed an excellent reusability (> 50 reuses). The method was applied to the 35 extraction and preconcentration of these analytes in water samples. The average 36 recoveries ranged from 79 ± 6 to 104 ± 3 %