1,012 research outputs found
Reduction and Unfolding for Quantum Systems: the Hydrogen Atom
In this paper we propose a ``quantum reduction procedure'' based on the
reduction of algebras of differential operators on a manifold. We use these
techniques to show, in a systematic way, how to relate the hydrogen atom to a
family of quantum harmonic oscillators, by the means of the
Kustaahneimo-Stiefel fibration.Comment: 22 pages, Latex 2e, typos correcte
The GiSAS study: Rationale and design of pragmatic randomized controlled trial on aripiprazole, olanzapine and haloperidol in the long-term treatment of schizophrenia
Given the controversy about the comparative efficacy of first- compared with second-generation antipsychotics in the treatment of schizophrenia, more large-scale evidence is needed to guide clinicians in their prescriptions. Most randomized controlled trials (RCTs) were conducted in centers of excellence on highly selected samples, poorly representative of real-world patients, and often suffered conflicts of interest as they were sponsored by drug companies.
The primary aim of the present study is to compare the effectiveness of haloperidol, olanzapine and aripiprazole in a representative sample of schizophrenia patients. The GiSAS trial is an open-label, independent, pragmatic RCT in Italian community-based public psychiatric services. At least 260 patients meeting the DSM-IV criteria for schizophrenia will be randomly allocated to one of the study drugs and followed up for one year. A two-year observational phase will follow. The primary outcome for tolerability will be the onset of metabolic syndrome. The primary endpoint for effectiveness will be discontinuation of antipsychotic monotherapy. Secondary measures include global functioning, time to discontinuation due to side-effects, change of lipid profile, extrapyramidal symptoms and other adverse effects.
In the last four years, the GiSAS study group has been working to implement this multicenter RCT. The trial mechanism is now fully functional and working. As of end of February 2011, 260 subjects were randomized by 54 study investigators in 33 out of 43 participating centers
CXOU J005047.9-731817: a 292-s X-ray binary pulsar in the Small Magellanic Cloud
We report on the discovery of a transient X-ray pulsars, located in the Small
Magellanic Cloud, with a pulse period of 292 s. A series of Chandra pointings
fortuitously recorded in 2010 April-May the occurrence of a two-weeks-long
outburst, during which the source luminosity increased by a factor of about
100, reaching a peak of ~1E36 erg/s (for a distance of 61 kpc). Complex-shape
and energy-dependent pulsations were detected close to the outburst peak and
during the very first part of its decay phase. During the outburst, the
phase-averaged spectrum of the pulsar was well described by an absorbed power
law with photon index ~0.6, but large variations as a function of phase were
present. The source was also detected by Chandra several times (during 2002,
2003, 2006, and 2010) at a quiescent level of ~1E34 erg/s. In 2012 we performed
an infrared photometric follow-up of the R ~ 15 mag optical counterpart with
the ESO/VLT and a spectroscopic observation by means of the CTIO telescope. The
optical spectra suggest a late-Oe or early-Be V-III luminosity-class star,
though a more evolved companion cannot be ruled out by our data (we can exclude
a luminosity class I and a spectral type later than B2). Finally, we show that
the outburst main parameters (duration and peak luminosity) can be accounted
for by interpreting the source transient activity as a type I outburst in a Be
X-ray binary.Comment: MNRAS, in press; 8 pages, 7 figures, 4 tables; Figure 1 in reduced
qualit
The faster the narrower: characteristic bulk velocities and jet opening angles of Gamma Ray Bursts
The jet opening angle theta_jet and the bulk Lorentz factor Gamma_0 are
crucial parameters for the computation of the energetics of Gamma Ray Bursts
(GRBs). From the ~30 GRBs with measured theta_jet or Gamma_0 it is known that:
(i) the real energetic E_gamma, obtained by correcting the isotropic equivalent
energy E_iso for the collimation factor ~theta_jet^2, is clustered around
10^50-10^51 erg and it is correlated with the peak energy E_p of the prompt
emission and (ii) the comoving frame E'_p and E'_gamma are clustered around
typical values. Current estimates of Gamma_0 and theta_jet are based on
incomplete data samples and their observed distributions could be subject to
biases. Through a population synthesis code we investigate whether different
assumed intrinsic distributions of Gamma_0 and theta_jet can reproduce a set of
observational constraints. Assuming that all bursts have the same E'_p and
E'_gamma in the comoving frame, we find that Gamma_0 and theta_jet cannot be
distributed as single power-laws. The best agreement between our simulation and
the available data is obtained assuming (a) log-normal distributions for
theta_jet and Gamma_0 and (b) an intrinsic relation between the peak values of
their distributions, i.e theta_jet^2.5*Gamma_0=const. On average, larger values
of Gamma_0 (i.e. the "faster" bursts) correspond to smaller values of theta_jet
(i.e. the "narrower"). We predict that ~6% of the bursts that point to us
should not show any jet break in their afterglow light curve since they have
sin(theta_jet)<1/Gamma_0. Finally, we estimate that the local rate of GRBs is
~0.3% of all local SNIb/c and ~4.3% of local hypernovae, i.e. SNIb/c with
broad-lines.Comment: 15 pages, 8 figures, 1 table. Accepted for publication in MNRA
Multiple tidal disruption flares in the active galaxy IC 3599
Tidal disruption events occur when a star passes too close to a massive black
hole and it is totally ripped apart by tidal forces. It may also happen that
the star is not close enough to the black hole to be totally disrupted and a
less dramatic event might happen. If the stellar orbit is bound and highly
eccentric, just like some stars in the centre of our own Galaxy, repeated
flares should occur. When the star approaches the black hole tidal radius at
periastron, matter might be stripped resulting in lower intensity outbursts
recurring once every orbital period. We report on Swift observations of a
recent bright flare from the galaxy IC 3599 hosting a middle-weight black hole,
where a possible tidal disruption event was observed in the early 1990s. By
light curve modelling and spectral fitting we can consistently account for the
events as the non-disruptive tidal stripping of a star into a highly eccentric
orbit. The recurrence time is 9.5 yr. IC 3599 is also known to host a
low-luminosity active galactic nucleus. Tidal stripping from this star over
several orbital passages might be able to spoon-feed also this activity.Comment: Accepted for publication to Astronomy & Astrophysic
The Swift X-ray Telescope Cluster Survey II. X-ray spectral analysis
(Abridged) We present a spectral analysis of a new, flux-limited sample of 72
X-ray selected clusters of galaxies identified with the X-ray Telescope (XRT)
on board the Swift satellite down to a flux limit of ~10-14 erg/s/cm2 (SWXCS,
Tundo et al. 2012). We carry out a detailed X-ray spectral analysis with the
twofold aim of measuring redshifts and characterizing the properties of the
Intra-Cluster Medium (ICM). Optical counterparts and spectroscopic or
photometric redshifts are obtained with a cross-correlation with NED.
Additional photometric redshifts are computed with a dedicated follow-up
program with the TNG and a cross-correlation with the SDSS. We also detect the
iron emission lines in 35% of the sample, and hence obtain a robust measure of
the X-ray redshift zX. We use zX whenever the optical redshift is not
available. Finally, for all the sources with measured redshift,
background-subtracted spectra are fitted with a mekal model. We perform
extensive spectral simulations to derive an empirical formula to account for
fitting bias. The bias-corrected values are then used to investigate the
scaling properties of the X-ray observables. Overall, we are able to
characterize the ICM of 46 sources. The sample is mostly constituted by
clusters with temperatures between 3 and 10 keV, plus 14 low-mass clusters and
groups with temperatures below 3 keV. The redshift distribution peaks around
z~0.25 and extends up to z~1, with 60% of the sample at 0.1<z<0.4. We derive
the Luminosity-Temperature relation for these 46 sources, finding good
agreement with previous studies. The quality of the SWXCS sample is comparable
to other samples available in the literature and obtained with much larger
X-ray telescopes. Our results have interesting implications for the design of
future X-ray survey telescopes, characterised by good-quality PSF over the
entire field of view and low background.Comment: 27 pages, 15 figures; minor typos corrected. To be published in A&A,
Volume 567, July 2014. Websites of the SWXCS project:
http://www.arcetri.astro.it/SWXCS/ and http://swxcs.ustc.edu.cn
GRB 140206A: the most distant polarized Gamma-Ray Burst
The nature of the prompt gamma-ray emission of Gamma-Ray Bursts (GRBs) is
still far from being completely elucidated. The measure of linear polarization
is a powerful tool that can be used to put further constraints on the content
and magnetization of the GRB relativistic outflows, as well as on the radiation
processes at work.
To date only a handful of polarization measurements are available for the
prompt emission of GRBs. Here we present the analysis of the prompt emission of
GRB 140206A, obtained with INTEGRAL/IBIS, Swift/BAT, and Fermi/GBM. Using
INTEGRAL/IBIS as a Compton polarimeter we were able to constrain the linear
polarization level of the second peak of this GRB as being larger than 28% at
90% c.l.
We also present the GRB afterglow optical spectroscopy obtained at the
Telescopio Nazionale Galileo (TNG), which allowed us the measure the distance
of this GRB, z=2.739. This distance value together with the polarization
measure obtained with IBIS, allowed us to derive the deepest and most reliable
limit to date (xi <1x10-16) on the possibility of Lorentz Invariance Violation,
measured through the vacuum birefringence effect on a cosmological source.Comment: 9 pages, 5 figures, 3 tables, accepted for publication in MNRAS.
arXiv admin note: text overlap with arXiv:1303.418
The puzzling case of the accreting millisecond X-ray pulsar IGR J00291+5934: flaring optical emission during quiescence
We present an optical (gri) study during quiescence of the accreting
millisecond X-ray pulsar IGR J00291+5934 performed with the 10.4m Gran
Telescopio Canarias (GTC) in August 2014. Despite the source being in
quiescence at the time of our observations, it showed a strong optical flaring
activity, more pronounced at higher frequencies (i.e. the g band). Once the
flares were subtracted, we tentatively recovered a sinusoidal modulation at the
system orbital period in all bands, even if a significant phase shift with
respect to an irradiated star, typical of accreting millisecond X-ray pulsars
is detected. We conclude that the observed flaring could be a manifestation of
the presence of an accretion disc in the system. The observed light curve
variability could be explained by the presence of a superhump, which might be
another proof of the formation of an accretion disc. In particular, the disc at
the time of our observations was probably preparing to the new outburst of the
source, that happened just a few months later, in 2015.Comment: 6 pages, 2 figures, 1 table. Accepted for publication in A&
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