Monocyte to lymphocyte blood ratio in tuberculosis and HIV patients: Comparative analysis, preliminary data

Recent data confirmed the hypothesis suggested by historical studies that the ratio of peripheral blood monocytes to lymphocytes (M/L) is associated with the risk of tuberculosis (TB) disease. We retrospectively analyzed the electronic health records of tuberculosis and HIV-positive patients who had followed day-care programs at the AIDS Center of the University of Palermo, Italy. 261 patients were recruited and divided into 6 groups as follows: healthy control group (HCG: 47 pts), latent HIV negative infected TB group (LIG, 43 pts), active HIV negative tuberculosis (TAG: 61 pts), treated tuberculosis HIV negative (TTG: 44 pts), HIV drug-naive patients tested TST and QFT-IT-negative with negative chest x-Ray (HIVnG: 44 pts), and HIV-tuberculosis coinfection (HIVTB-G: 22 pts). For each group, absolute lymphocyte (L), monocyte (M) and M/L ratio by peripheral blood was calculated. The mean value of monocytes in the TAG group was significant, the highest (0.70\uc2\ub10.37 1x103/\uce\ubcl) in comparison to HGC (0.70>0.44, p-value <0.05), HIVnG (0.70>0.40, p-value <0.05) and HIVTB-G (0.70>0.45, p-value<0.05). Monocyte to lymphocyte blood RATIO showed a significant difference between groups (p-value <0.001). In particular, the mean score of M/L ratio was higher in the TAG group compared to the HGC (0.49>0.27, p-value<0.05), LIG (0.49>0.29, p-value<0.05), TTG (0.49>0.32) and HIVTB-G groups (0.49>0.27, p-value<0.05). Our data confirm a significant difference in monocyte to lymphocyte blood ratio in tuberculosis disease. These data may be useful for monitoring and revising implementation plans for the different phases of tuberculosis disease (latent Mycobacterium tuberculosis (MTB) infection versus TB active disease). Regarding HIV samples, the small sample size is somewhat offset by the need, fully satisfied in our sample, to enlist specific patients such as co-infected HIV/TBC who voluntarily submit to clinical trials in our geographical area

Ageing test of the ATLAS RPCs at X5-GIF

An ageing test of three ATLAS production RPC stations is in course at X5-GIF, the CERN irradiation facility. The chamber efficiencies are monitored using cosmic rays triggered by a scintillator hodoscope. Higher statistics measurements are made when the X5 muon beam is available. We report here the measurements of the efficiency versus operating voltage at different source intensities, up to a maximum counting rate of about 700Hz/cm^2. We describe the performance of the chambers during the test up to an overall ageing of 4 ATLAS equivalent years corresponding to an integrated charge of 0.12C/cm^2, including a safety factor of 5.Comment: 4 pages. Presented at the VII Workshop on Resistive Plate Chambers and Related Detectors; Clermont-Ferrand October 20th-22nd, 200

Using earthquakes to uncover the Earth's inner secrets: interactive exhibits for geophysical education

International audienceThe Educational & Outreach Group (E&O Group) of the Istituto Nazionale di Geofisica e Vulcanologia (INGV) designed a portable museum to bring on the road educational activities focused on seismology, seismic hazard and Earth science. This project was developed for the first edition of the Science Festival organized in Genoa, Italy, in 2003. The museum has been mainly focused to school students of all ages and explains the main topics of geophysics through posters, movie and slide presentations, and exciting interactive experiments. This new INGV museum has been remarkably successful, being visited by more than 8000 children and adults during the 10 days of the Science Festival. It is now installed at the INGV headquarters in Rome and represents the main attraction during the visits of the schools all year round

Using earthquakes to uncover the Earth's inner secrets: interactive exhibits for geophysical education

The Educational &amp; Outreach Group (E&amp;O Group) of the Istituto Nazionale di Geofisica e Vulcanologia (INGV) designed a portable museum to bring on the road educational activities focused on seismology, seismic hazard and Earth science. This project was developed for the first edition of the Science Festival organized in Genoa, Italy, in 2003. <P style=&quot;line-height: 20px;&quot;> The museum has been mainly focused to school students of all ages and explains the main topics of geophysics through posters, movie and slide presentations, and exciting interactive experiments. This new INGV museum has been remarkably successful, being visited by more than 8000 children and adults during the 10 days of the Science Festival. It is now installed at the INGV headquarters in Rome and represents the main attraction during the visits of the schools all year round