La disautonomía felina (Síndrome de Key-Gaskell) : caso clínico

Un caso de disautonomía felina en un gato de 10 meses (síndrome de Key-Gaskell). Los síntomas clínicos reflejaron disfunción simpática y parasimpática del sistema nervioso autónomo. E diagnóstico fue basado en la obtención de un grado 4 por el sistema de graduación por síntomas para disautonomía felina propuesto por Sharp (1989). Los síntomas más destacados fueron: midriasis bilateral sin respuesta a la luz, protusión bilateral del tercer párpado, reducción de la secreción lacrimal, regurguitación, retención urinaria, estreñimiento y bradicardia. El animal necesitó ser eutanasiado al cuarto día de hospitalización

The Nature of Occupational Unemployment Rates in the United States: Hysteresis or Structural?

This paper provides new evidence on the nature of occupational differences in unemployment dynamics, which is relevant for the debate between the structural or hysteresis hypotheses. We develop a procedure that permits us to test for the presence of a structural break at unknown date. Our approach allows the investigation of a broader range of persistence than the 0/1 paradigm about the order of integration, usually implemented for testing the hypothesis of hysteresis in occupational unemployment. In almost all occupations, we find support for both the structuralist and the hysteresis hypotheses, but stress the importance of estimating the degree of persistence of seasonal shocks along with the degree of long-run persistence on raw data without applying seasonal filters. Indeed hysteresis appears to be underestimated when data are initially adjusted using traditional seasonal filters.fractional integration, structural break, occupational unemployment, structuralist, hysteresis

Contamination nitratée des eaux souterraines d'un bassin versant agricole hétérogène 2. Évolution des concentrations dans la nappe

L'usage quasi systématique de fertilisants sur de grandes surfaces a conduit la majorité des aquifères superficiels à un grave niveau de contamination par les nitrates. Des essais de gestion environnementale de cette problématique agricole sont conduits à l'échelle du bassin versant afin d'estimer les flux de nitrates percolant vers la nappe. La présente étude reprend les résultats issus de la modélisation d'un bassin versant dans le but d'appréhender l'évolution de la concentration en nitrates dans les eaux de la nappe. L'importance des conditions hydrogéologiques dans les relations entre zones non saturée et saturée a été mise en évidence par la comparaison des concentrations calculées dans la zone non saturée et observées dans la nappe. En règle générale, les concentrations sont très semblables pour les zones proches des limites amont du bassin, et se différencient de plus en plus vers l'aval du système. Une dilution semble se produire entre les flux percolant des différentes zones non saturées et les flux d'eau et de nitrates s'écoulant dans l'aquifère. Afin de tester cette hypothèse, un modèle de dilution basé sur les flux d'eau et de nitrates dans les zones non saturée et saturée est développé. Appliqué sur l'axe d'écoulement principal du système, le modèle de dilution permet de reproduire adéquatement les concentrations observées dans la nappe à partir de celles calculées dans le sol avec une erreur maximale variant de 1 à 22%. Le couplage d'un modèle environnemental pour la zone racinaire du sol avec un modèle de dilution simple peut permettre le calcul des concentrations en nitrates dans la zone saturée. Toutefois, la prise en compte des conditions hydrogéologiques du système est nécessaire à un calcul de dilution efficace basé sur les valeurs des flux de percolation.Pesticides and nitrates represent the main sources of aquifer contamination in agricultural zones. In many regions, nitrate concentration levels reach and exceed the water quality criteria (50 mg NO3/L). The increasing use of mineral fertilizers (which has doubled during the 20 last years) and the intensive exploitation of the aquifers for crop irrigation (1,1 million ha in France) have led to groundwater contamination by nitrates. The dynamics (long-term persistence) and extensiveness (regional contamination) of this contamination make it a sensitive environmental issue. Comprehensive environmental management is needed in order to limit the increase of the concentration levels and to reduce the extent of the contaminated areas. During the last few years, research has been done in the field of watershed management, from laboratory experiments to field investigations. At the same time, numerous simulation models have been developed at different investigation scales. Banton et al. (1993) developed a model specifically devoted to environmental management. Their model, AgriFlux, is based on a mechanistic approach to the processes, using a stochastic method that takes into account the spatial variability of the parameters. AgriFlux calculates the nitrate concentrations as well as the water fluxes in the unsaturated zone. The concentrations in the unsaturated zone (obtained by modeling or measurement) are generally dissimilar to those observed in the saturated zone (i.e. in the aquifer) because the infiltration water is diluted in the aquifer water. This difference indicates that the concentrations in the unsaturated zone cannot be used to accurately evaluate the actual risk of groundwater contamination. Hydrogeological conditions such as the recharge limits, the flow direction and the flow rate should be incorporated into the evaluation. In this paper, the modeling results obtained previously (Dupuy et al., 1997) with AgriFlux for the La Jannerie watershed are used to determine the concentrations in the aquifer and to compare them with the concentrations measured in the observation wells. This watershed (160 ha) is used exclusively for agriculture. The fractured carbonate strata (Superior Oxfordian) constitute a phreatic aquifer with a vertical extension of about 20 m. First, the temporal evolution of the annual mean concentrations in the aquifer is compared with the evolution of the annual precipitation. The results show that the mean concentrations tend to follow precipitation levels. However, the differences observed at different locations in the watershed cannot be explained by these results. The spatial evolution of the concentrations from the upstream to the downstream part of the aquifer was studied in order to explain the concentration distribution in the watershed. On the main flow line, the concentrations observed from 1985 to 1989 show a decrease from the P7 well (upstream) to the P26 well (downstream). This phenomenon can be attributed to two factors. First, denitrification may occur in the aquifer during flow. However, it is recognized in literature that the denitrification rate is usually low and a long period of time is required to obtain a significant decrease in the nitrate level. The observed attenuation cannot be imputed to this factor alone. The second possible cause is related to the dilution of the nitrates in the water contained in the aquifer.In order to test this hypothesis, a dilution model was elaborated using the watershed division as indicated in Dupuy et al. (1997). In each area, the resulting concentration is obtained by diluting the fluxes of water and nitrate leaching in the unsaturated zone in the fluxes of water and nitrates flowing from the upstream area. The concentrations in the aquifer are calculated from upstream areas to downstream areas for the period between 1985 and 1989. The pattern of the concentration curves obtained in this manner agrees with the trend measured in the different wells. The results clearly show a decrease of the concentration in the aquifer water leached from the unsaturated zone. For the downstream area (well P26), the calculated concentrations are higher than the observed ones. This difference could be due to the fact that the lateral fluxes (flow convergence into the median part) are not taken into account and the concentrations may thus be overestimated. However, the mean resulting error (12%) remains low considering the lack of knowledge of the aquifer characteristics. It is therefore possible to accurately estimate the nitrate concentrations in the saturated zone from the concentrations simulated in the unsaturated zone using a simple dilution model. However, this method is only valid for simple hydrogeological conditions

Transparent soil for imaging the rhizosphere

Understanding of soil processes is essential for addressing the global issues of food security, disease transmission and climate change. However, techniques for observing soil biology are lacking. We present a heterogeneous, porous, transparent substrate for in situ 3D imaging of living plants and root-associated microorganisms using particles of the transparent polymer, Nafion, and a solution with matching optical properties. Minerals and fluorescent dyes were adsorbed onto the Nafion particles for nutrient supply and imaging of pore size and geometry. Plant growth in transparent soil was similar to that in soil. We imaged colonization of lettuce roots by the human bacterial pathogen Escherichia coli O157:H7 showing micro-colony development. Micro-colonies may contribute to bacterial survival in soil. Transparent soil has applications in root biology, crop genetics and soil microbiology

Tratamiento quimioterápico del carcinoma de células de transición de la vejiga urinaria en dos perros

Se presentan dos casos de carcinoma de células transicionales (CCT) en una perra hembra (cuello vesical) y un macho (cuerpo viscal). En el segundo caso se realizó resección de tumor. Ambos fueron tratados con mitoxantrona y piroxicam. El primer caso sobrevivió 144 días y el segundo murió a los tres años.

Orbital Parameter Determination for Wide Stellar Binary Systems in the Age of Gaia

The orbits of binary stars and planets, particularly eccentricities and inclinations, encode the angular momentum within these systems. Within stellar multiple systems, the magnitude and (mis)alignment of angular momentum vectors among stars, disks, and planets probes the complex dynamical processes guiding their formation and evolution. The accuracy of the \textit{Gaia} catalog can be exploited to enable comparison of binary orbits with known planet or disk inclinations without costly long-term astrometric campaigns. We show that \textit{Gaia} astrometry can place meaningful limits on orbital elements in cases with reliable astrometry, and discuss metrics for assessing the reliability of \textit{Gaia} DR2 solutions for orbit fitting. We demonstrate our method by determining orbital elements for three systems (DS Tuc AB, GK/GI Tau, and Kepler-25/KOI-1803) using \textit{Gaia} astrometry alone. We show that DS Tuc AB's orbit is nearly aligned with the orbit of DS Tuc Ab, GK/GI Tau's orbit might be misaligned with their respective protoplanetary disks, and the Kepler-25/KOI-1803 orbit is not aligned with either component's transiting planetary system. We also demonstrate cases where \textit{Gaia} astrometry alone fails to provide useful constraints on orbital elements. To enable broader application of this technique, we introduce the python tool \texttt{lofti\_gaiaDR2} to allow users to easily determine orbital element posteriors.Comment: 18 pages, 10 figures, accepted for publication in Ap