1,919 research outputs found

    Theory of the SrTiO3 Surface State Two-Dimensional Electron Gas

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    We present a theory of the quasi two-dimensional electron gas (2DEG) systems which appear near the surface of SrTiO3_3 when a large external electric field attracts carriers to the surface. We find that non-linear and non-local screening by the strongly polarizable SrTiO3_3 lattice plays an essential role in determining 2DEG properties. The electronic structure always includes weakly bound bulk-like bands that extend over many SrTiO3_3 layers. At 2D carrier-densities exceeding 1014cm2\sim 10^{14} {\rm cm}^{-2} tightly bound bands emerge that are confined within a few layers of the surface.Comment: 10 pages, 9 figures, 1 tabl

    Corporate Portal Management System

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    Web Portal Software Systems have become a very effective communication medium for sharing. Our Portal Management System dramatically simplifies the creation and management of portals. A corporate portal is a web-based platform to access with security a broad range of information, services, applications and expertise. The corporate portal management system platform offers a flexible and robust content management solution that allows employees, customers and partners to safely collaborate on, contribute to and manage business content anywhere around the world. It can be utilised as an extranet that serves both internal and external users or as an intranet for internal communication in an organisation. Corporate portals can also provide single sign-on capabilities between their users and various other systems. The focus of our software is on presenting documents and content in an effective manner to individuals, groups, customers, partners and vendors. Portal content, services and applications can be customized and personalized to the need of different users or user groups. Content will be published on portal by a content management tool. Before publishing the content, it will be approved by management by using workflow. The basic and the most important function of the Corporate Portal Management System is the routing of data using the concept of workflow along with the various features like scheduling, commenting module and other similar features which make the software using service highly interactive and communicative. The use of this software can result in a reduction in the number of man hours spent in moderating the content on any portal. It also provides an easy to understand and intuitive interface for users which greatly helps in adapting to the use of this software

    Microwave photovoltage and photoresistance effects in ferromagnetic microstrips

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    We investigate the dc electric response induced by ferromagnetic resonance in ferromagnetic Permalloy (Ni80Fe20) microstrips. The resulting magnetization precession alters the angle of the magnetization with respect to both dc and rf current. Consequently the time averaged anisotropic magnetoresistance (AMR) changes (photoresistance). At the same time the time-dependent AMR oscillation rectifies a part of the rf current and induces a dc voltage (photovoltage). A phenomenological approach to magnetoresistance is used to describe the distinct characteristics of the photoresistance and photovoltage with a consistent formalism, which is found in excellent agreement with experiments performed on in-plane magnetized ferromagnetic microstrips. Application of the microwave photovoltage effect for rf magnetic field sensing is discussed.Comment: 16 pages, 15 figure

    Mutations in phosphodiesterase 6 identified in familial cases of retinitis pigmentosa.

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    To delineate the genetic determinants associated with retinitis pigmentosa (RP), a hereditary retinal disorder, we recruited four large families manifesting cardinal symptoms of RP. We localized these families to regions on the human genome harboring the α and β subunits of phosphodiesterase 6 and identified mutations that were absent in control chromosomes. Our data suggest that mutations in PDE6A and PDE6B are responsible for the retinal phenotype in these families

    Impact of Medical Education Trend in Community Development

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    Problem-based learning has been described as one of the most significant developments in medical education. The trend of medical education plays a vital role in determining the success of universal health coverage in India.  The motto of health education is community-based training, where students are placed in the community and learn by delivering the care using the existing health services

    Tunable Microstrip Filters Using Selectively Etched Ferroelectric Thin-Film Varactors for Coupling

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    We report on the use of patterned ferroelectric films to fabricate proof of concept tunable one-pole microstrip filters with excellent transmission and mismatch/reflection properties at frequencies up to 24 GHz. By controlling the electric field distribution within the coupling region between the resonator and input/output lines, sufficiently high loaded and unloaded Q values are maintained so as to be useful for microstrip filter design, with low mismatch loss. In the 23 - 24 GHz region, the filter was tunable over a 100 MHz range, the loaded and unloaded Q values were 29 and 68, respectively, and the reflection losses were below -16 dB, which demonstrates the suitability of these films for practical microwave applications

    Folic Acid Functionalized Nanoparticles for Enhanced Oral Drug Delivery

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    The oral absorption of drugs that have poor bioavailability can be enhanced by encapsulation in polymeric nanoparticles. Transcellular transport of nanoparticle-encapsulated drug, possibly through transcytosis, is likely the major mechanism through which nanoparticles improve drug absorption. We hypothesized that the cellular uptake and transport of nanoparticles can be further increased by targeting the folate receptors expressed on the intestinal epithelial cells. The objective of this research was to study the effect of folic acid functionalization on transcellular transport of nanoparticle-encapsulated paclitaxel, a chemotherapeutic with poor oral bioavailability. Surface-functionalized poly(D,L-lactide-co-glycolide) (PLGA) nanoparticles loaded with paclitaxel were prepared by the interfacial activity assisted surface functionalization technique. Transport of paclitaxel-loaded nanoparticles was investigated using Caco-2 cell monolayers as an in vitro model. Caco-2 cells were found to express folate receptor and the drug efflux protein, p-glycoprotein, to high levels. Encapsulation of paclitaxel in PLGA nanoparticles resulted in a 5-fold increase in apparent permeability (P(app)) across Caco-2 cells. Functionalization of nanoparticles with folic acid further increased the transport (8-fold higher transport compared to free paclitaxel). Confocal microscopic studies showed that folic acid-functionalized nanoparticles were internalized by the cells and that nanoparticles did not have any gross effects on tight junction integrity. In conclusion, our studies indicate that folic acid functionalized nanoparticles have the potential to enhance the oral absorption of drugs with poor oral bioavailability

    A Study to Assess the Effectiveness of Rhythmic Auditory Stimulation along with Neurodevelopmental Therapy in improving the Gait Pattern of Post Stroke patients

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    INTRODUCTION: Gait restoration after stroke is a major concern of neurological rehabilitation. Stroke is the major cause of disability and raising mare number of handicaps in this industrialized world. In India thy rate of people affected by stroke is keep on increasing because of poor life style and other major factors. The need of rehabilitation after stroke places an important role to make the patient functionally independent in all aspect of basic life style. Physiotherapist is one of the team members who treat the patient in gross motor aspect. AIM OF THE STUDY: The aim of the study is to find the efficacy of combined treatment (Rhythmic auditory stimulation and Neuro Developmental Treatment approach) in improving the gait pattern of post stroke patient. MATERIALS AND METHODOLOGY: MATERIALS: Couch, Foot stool, Blocks\steps, Chalk, Inch tape, Ramp. METHODOLOGY: Study Design: Pre test – Post test experimental study design. Study setting: Health Care Institutes approved by college and Guide. Sampling Method: Simple random sampling method. Sample size: A total number of 10 subjects diagnosed as stroke were taken for the study. Study Duration: The study was conducted for a period of 3 months. Inclusion criteria: • Age 40 to 65 years. • Sex – both male and female. • Able to walk 10 meter independently. • Hemiplegia due to cerebrovascular accident of more than 3 months duration. Exclusion criteria: • Cerebellar ataxia. • Impaired cognitive function. • Aphasia. • Basal ganglion lesion. • Unconscious patient. • Condition that affect mobility like arthritis disease, spinal abnormalities (or) any amputations. • Communicative disorder. RESULT: The most common cause for stroke is due to occlusion of one of the major cerebral artery especially anterior cerebral artery. The stroke patient has reduced functional mobility and reduced leg function and spasticity. Deana and Richards (2000) suggested that rhythmic auditory stimulation along with NDT training had a greater contribution in improving the lower limb extensor muscles after the intervention. At thighs-off, the centre of the body mass has moved forward over the feet. This position ensures that the relative position of body segment at thighs-off enables lower limb extensor forces to accelerate the body vertically into the standing position. (Carr 2009). Stepping up and down in difference direction (forward and sideways) strengthen difference synergic relationship between hip, knee, ankle extensor and hip abductors or adductors to train in different pattern muscles activation and flexible walking performance. (Shepherd 2000). Repetitive stepping exercise using of various steps of various heights increase the strength in the lower extensor muscle. Reaching forward, sideways and in different direction help the individual regain strength and control of the lower limbs, which may enable them to take more weight through the affected leg. Therefore there is mounting evidence that progressive resistance training is effective in improving gait pattern following stroke. CONCLUSION: The study concluded that was the rhythmic auditory stimulation along with NDT effective treatment for improving gait pattern in stroke patients. And also step length and stride length test could be used as the assessment tool for stroke patients
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