477 research outputs found
Models of cuspy triaxial stellar systems. II. Regular orbits
In the first paper of this series we used the N--body method to build a dozen
cuspy (gamma ~ 1) triaxial models of stellar systems, and we showed that they
were highly stable over time intervals of the order of a Hubble time, even
though they had very large fractions of chaotic orbits (more than 85 per cent
in some cases). The models were grouped in four sets, each one comprising
models morphologically resembling E2, E3, E4 and E5 galaxies, respectively. The
three models within each set, although different, had the same global
properties and were statistically equivalent. In the present paper we use
frequency analysis to classify the regular orbits of those models. The bulk of
those orbits are short axis tubes (SATs), with a significant fraction of long
axis tubes (LATs) in the E2 models that decreases in the E3 and E4 models to
become negligibly small in the E5 models. Most of the LATs in the E2 and E3
models are outer LATs, but the situation reverses in the E4 and E5 models where
the few LATs are mainly inner LATs. As could be expected for cuspy models, most
of the boxes are resonant orbits, i.e., boxlets. Nevertheless, only the (x, y)
fishes of models E3 and E4 amount to about 10 per cent of the regular orbits,
with most of the fractions of the other boxlets being of the order of 1 per
cent or less.Comment: Accepted for publication in the Monthly Notices of the Royal
Astronomical Societ
Precision Measurements of Stretching and Compression in Fluid Mixing
The mixing of an impurity into a flowing fluid is an important process in
many areas of science, including geophysical processes, chemical reactors, and
microfluidic devices. In some cases, for example periodic flows, the concepts
of nonlinear dynamics provide a deep theoretical basis for understanding
mixing. Unfortunately, the building blocks of this theory, i.e. the fixed
points and invariant manifolds of the associated Poincare map, have remained
inaccessible to direct experimental study, thus limiting the insight that could
be obtained. Using precision measurements of tracer particle trajectories in a
two-dimensional fluid flow producing chaotic mixing, we directly measure the
time-dependent stretching and compression fields. These quantities, previously
available only numerically, attain local maxima along lines coinciding with the
stable and unstable manifolds, thus revealing the dynamical structures that
control mixing. Contours or level sets of a passive impurity field are found to
be aligned parallel to the lines of large compression (unstable manifolds) at
each instant. This connection appears to persist as the onset of turbulence is
approached.Comment: 5 pages, 5 figure
Multifractal Scaling, Geometrical Diversity, and Hierarchical Structure in the Cool Interstellar Medium
Multifractal scaling (MFS) refers to structures that can be described as a
collection of interwoven fractal subsets which exhibit power-law spatial
scaling behavior with a range of scaling exponents (concentration, or
singularity, strengths) and dimensions. The existence of MFS implies an
underlying multiplicative (or hierarchical, or cascade) process. Panoramic
column density images of several nearby star- forming cloud complexes,
constructed from IRAS data and justified in an appendix, are shown to exhibit
such multifractal scaling, which we interpret as indirect but quantitative
evidence for nested hierarchical structure. The relation between the dimensions
of the subsets and their concentration strengths (the "multifractal spectrum'')
appears to satisfactorily order the observed regions in terms of the mixture of
geometries present: strong point-like concentrations, line- like filaments or
fronts, and space-filling diffuse structures. This multifractal spectrum is a
global property of the regions studied, and does not rely on any operational
definition of "clouds.'' The range of forms of the multifractal spectrum among
the regions studied implies that the column density structures do not form a
universality class, in contrast to indications for velocity and passive scalar
fields in incompressible turbulence, providing another indication that the
physics of highly compressible interstellar gas dynamics differs fundamentally
from incompressible turbulence. (Abstract truncated)Comment: 27 pages, (LaTeX), 13 figures, 1 table, submitted to Astrophysical
Journa
Phase separation in a chaotic flow
The phase separation between two immiscible liquids advected by a
bidimensional velocity field is investigated numerically by solving the
corresponding Cahn-Hilliard equation. We study how the spinodal decomposition
process depends on the presence -or absence- of Lagrangian chaos. A fully
chaotic flow, in particular, limits the growth of domains and for unequal
volume fractions of the liquids, a characteristic exponential distribution of
droplet sizes is obtained. The limiting domain size results from a balance
between chaotic mixing and spinodal decomposition, measured in terms of
Lyapunov exponent and diffusivity constant, respectively.Comment: Minor changes - Version accepted for publication - Physical Review
Letter
Association between β2-adrenoceptor (ADRB2) haplotypes and insulin resistance in PCOS
OBJECTIVE: The aim of this study was to explore β2-adrenoceptor (ADRB2) haplotype associations with phenotypes and quantitative traits related to insulin resistance (IR) and the metabolic syndrome (MS) in a polycystic ovary syndrome (PCOS) population. A secondary purpose was to assess the association between ADRB2 haplotype and PCOS. DESIGN: Genetic polymorphism analysis. Cross-sectional case-control association study. SETTING: Medical University Hospital and research laboratory. PATIENTS: One hundred and sixty-five unrelated women with PCOS and 116 unrelated women without PCOS (control sample). MEASUREMENTS: Clinical and biochemical measurements, and ADRB2 genotyping in PCOS patients and control subjects. METHODS: ADRB2 haplotypes (comprising rs1042711, rs1801704, rs1042713 and rs1042714 in that order), genotyping and statistical analysis to evaluate associations with continuous variables and traits related to IR and MS in a PCOS population. Associations between ADRB2 haplotypes and PCOS were also assessed. RESULTS: We observed an age-adjusted association between ADRB2 haplotype CCGG and lower insulin (P = 0·018) and HOMA (P = 0·008) in the PCOS sample. Interestingly, the expected differences in surrogate measures of IR between cases and controls were not significant in CCGG/CCGG carriers. In the case-control study, genotype CCGG/CCGG was associated with a 14% decrease in PCOS risk (P = 0·043), taking into account confounding variables. CONCLUSIONS: Haplotype I (CCGG) has a protective role for IR and MS in PCOS.Fil: Tellechea, Mariana Lorena. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Estudios de la Inmunidad Humoral Prof. Ricardo A. Margni. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Instituto de Estudios de la Inmunidad Humoral Prof. Ricardo A. Margni; Argentina. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Departamento de Microbiología, Inmunología y Biotecnología. Cátedra de Genética y Biología Molecular; ArgentinaFil: Muzzio, Damián Oscar. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Departamento de Microbiología, Inmunología y Biotecnología. Cátedra de Genética y Biología Molecular; ArgentinaFil: Iglesias Molli, Andrea Elena. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Departamento de Microbiología, Inmunología y Biotecnología. Cátedra de Genética y Biología Molecular; ArgentinaFil: Belli, Susana H.. Hospital Carlos Durand; ArgentinaFil: Graffigna, Mabel N.. Hospital Carlos Durand; ArgentinaFil: Levalle, Oscar A.. Hospital Carlos Durand; ArgentinaFil: Frechtel, Gustavo Daniel. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Departamento de Microbiología, Inmunología y Biotecnología. Cátedra de Genética y Biología Molecular; Argentina. Universidad de Buenos Aires. Facultad de Medicina. Hospital de Clínicas General San Martín; ArgentinaFil: Cerrone, Gloria Edith. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Departamento de Microbiología, Inmunología y Biotecnología. Cátedra de Genética y Biología Molecular; Argentin
HDAC I Inhibition in the Dorsal and Ventral Hippocampus Differentially Modulates Predator-Odor Fear Learning and Generalization
Although predator odors are ethologically relevant stimuli for rodents, the molecular pathways and contribution of some brain regions involved in predator odor conditioning remain elusive. Inhibition of histone deacetylases (HDACs) in the dorsal hippocampus has been shown to enhance shock-induced contextual fear learning, but it is unknown if HDACs have differential effects along the dorso-ventral hippocampal axis during predator odor fear learning. We injected MS-275, a class I HDAC inhibitor, bilaterally in the dorsal or ventral hippocampus of mice and found that it had no effects on innate anxiety in either region. We then assessed the effects of MS-275 at different stages of fear learning along the longitudinal hippocampal axis. Animals were injected with MS-275 or vehicle after context pre-exposure (pre-conditioning injections), when a representation of the context is first formed, or after exposure to coyote urine (post-conditioning injections), when the context becomes associated with predator odor. When MS-275 was administered after context pre-exposure, dorsally injected animals showed enhanced fear in the training context but were able to discriminate it from a neutral environment. Conversely, ventrally injected animals did not display enhanced learning in the training context but generalized the fear response to a neutral context. However, when MS-275 was administered after conditioning, there were no differences between the MS-275 and vehicle control groups in either the dorsal or ventral hippocampus. Surprisingly, all groups displayed generalization to a neutral context, suggesting that predator odor exposure followed by a mild stressor such as restraint leads to fear generalization. These results may elucidate distinct functions of the dorsal and ventral hippocampus in predator odor-induced fear conditioning as well as some of the molecular mechanisms underlying fear generalization
Analytical derivation of the probability for the escape of stars from colliding galaxies
We use the impulse approximation to derive analytical formulae for the escape probability from a simple binary system that interacts with a third body. The binary system is made up of a mass-less body in circular orbit around a massive object, and we assume that the two massive bodies follow a Schuster (or Plummer) distribution. Within the ranges imposed by the impulsive approximation to the parameters of the encounter, we find good agreement between our results and those obtained from numerical experiments.Facultad de Ciencias Astronómicas y Geofísica
Models of cuspy triaxial stellar systems. I. Stability and chaoticity
We used the N-body code of Hernquist and Ostriker (1992) to build a dozen
cuspy ({\gamma}\approx 1) triaxial models of stellar systems through
dissipationless collapses of initially spherical distributions of 10^6
particles. We chose four sets of initial conditions that resulted in models
morphologically resembling E2, E3, E4 and E5 galaxies, respectively. Within
each set, three different seed numbers were selected for the random number
generator used to create the initial conditions, so that the three models of
each set are statistically equivalent. We checked the stability of our models
using the values of their central densities and of their moments of inertia,
which turned out to be very constant indeed. The changes of those values were
all less than 3 per cent over one Hubble time and, moreover, we show that the
most likely cause of those changes are relaxation effects in the numerical
code. We computed the six Lyapunov exponents of nearly 5,000 orbits in each
model in order to recognize regular, partially and fully chaotic orbits. All
the models turned out to be highly chaotic, with less than 25 per cent of their
orbits being regular. We conclude that it is quite possible to obtain cuspy
triaxial stellar models that contain large fractions of chaotic orbits and are
highly stable. The difficulty to build such models with the method of
Schwarzschild (1979) should be attributed to the method itself and not to
physical causes.Comment: 10 pages, 5 figures, published in MNRAS (The definitive version is
available at www.blackwell-synergy.com
Oscilaciones radiales de sistemas estelares esféricos
unque el uso del teorema del virial para determinar condiciones de equilibrio de sistemas estelares es muy frecuente, no está tan difundida su aplicación para analizar oscilaciones de esos mismos sistemas, aún cuando la misma es conocida desde hace tiempo (S. Chandrasekhar y D.D. Elbert, 1972, M.N.R.A.S. 155, 435). El muy reciente estudio numérico de W.L. Sweatman (1993, M.N.R.A.S. 261, 497) ha vuelto a poner sobre el tapete el problema de las oscilaciones radiales de sistemas esféricos. Hemos retomado y extendido la técnica de Chandrasekhar y Elbert para estudiar este problema, extendiéndolo con las técnicas de dinámica no lineal a situaciones caóticas y de inestabilidad.Asociación Argentina de Astronomí
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