Theory of Coupled Resonator Optical Waveguides (CROW) Exhibiting High Order Exceptional Points of Degeneracy

We present a novel approach and a theoretical framework for generating high order exceptional points of degeneracy (EPD) in photonic structures based on periodic coupled resonators optical waveguides (CROWs). Such EPDs involve the coalescence of Floquet-Bloch eigenwaves in CROWs, without the presence of gain and loss, which is in contrast to the requirement of Parity-Time (PT) symmetry to develop exceptional points based on gain and loss balance. The EPDs arise here by introducing symmetry breaking in a conventional chain of coupled resonators through coupling the chain of resonators to an adjacent uniform optical waveguide, which leads to unique modal characteristics that cannot be realized in conventional CROWs. Such remarkable characteristics include high quality factors (Q-factor) and strong field enhancement, even without any mirrors at the two ends of a cavity. We show for the first time the capability of CROWs to exhibit EPDs of various order; including the degenerate band edge (DBE) and the stationary inflection point (SIP). The proposed CROW of finite length shows enhanced quality factor when operating near the DBE, and the Q-factor exhibits an anomalous scaling with the CROW's length. We develop the theory of EPDs in such unconventional CROW using coupled-wave equations, and we derive an analytical expression for the dispersion relation. The proposed unconventional CROW concepts have various potential applications including Q-switching, nonlinear devices, lasers, and extremely sensitive sensors.Comment: 16 pages, 11 figure

Spontaneous Coronary Artery Dissection : The Phantom Menace

Articles © The authorsWe present a case of a 66-year-old lady with chest pain, without dynamic 12-lead electrocardiographic (ECG) changes and normal serial troponin. Coronary angiography revealed a linear filing defect in the first obtuse marginal branch of the circumflex artery indicating coronary artery dissection, with superadded thrombus. She was managed medically with dual antiplatelet therapy and has responded well. Spontaneous coronary artery dissection (SCAD) is a rare cause of cardiac chest pain, which can be missed without coronary angiography. Unlike most other lesions in patients with unstable symptoms, where coronary intervention with stenting is recommended, patients with SCAD generally fare better with conservative measures than with intervention, unless there is hemodynamic instability.Peer reviewe

Coastline Kriging: A Bayesian Approach

Statistical interpolation of chemical concentrations at new locations is an important step in assessing a worker's exposure level. When measurements are available from coastlines, as is the case in coastal clean-up operations in oil spills, one may need a mechanism to carry out spatial interpolation at new locations along the coast. In this paper we present a simple model for analyzing spatial data that is observed over a coastline. We demonstrate four different models using two different representations of the coast using curves. The four models were demonstrated on simulated data and one of them was also demonstrated on a dataset from the GuLF STUDY. Our contribution here is to offer practicing hygienists and exposure assessors with a simple and easy method to implement Bayesian hierarchical models for analyzing and interpolating coastal chemical concentrations

Evaluation of Biological Control Potential for Different Trichoderma Strains Against Root-Knot Nematode Meloidogyne Javanica

Twenty strains of four Trichoderma species (Trichoderma harzianum, Trichoderma viride, Trichoderma koningii and Trichoderma asperellum) were evaluated for its potential to control the root-knot nematode Meloidogyne javanica. Culture filtrates from Trichoderma strains were tested in 24-well tissue culture plates for effects on Meloidogyne javanica. Chitwood egg hatch and mobility of hatched second-stage juveniles (J2) were evaluated, all the twenty Trichoderma strains showed the ability to colonize M. javanica separated eggs and second-stage juveniles (J2) in sterile in vitro assays. T. asperellum possess the strongest egg-parasitic ability and very effective against 2nd stage larvae of M. javanica. In this investigation, randomly amplified polymorphic DNA (RAPD) markers was used to estimate the genetic variations between four strains of Trichoderma asperellum (KC898190, KC898191, KC898192 and KC898193) which were previously isolated from the rhizospheres of different plants growing in Fayoum Governorate, Egypt as a new strain of T. asperellum in Egypt. RAPD assay using 6 random primers identified T. asperellum strains with 5 specific unique markers

Karakteristik Fasade Bangunan Untuk Pelestarian Koridor Jalan Panggung Surabaya

Sejarah panjang kota Surabaya yang dimulai sejak zaman Kerajaan Hindu – Mataram sampai kolonial Belanda (Handinoto, 1996) membentuk budaya yang beragam bagi kota Surabaya. Di koridor Jalan Panggung yang termasuk dalam kawasan Pecinan Surabaya, masih terdapat beberapa bangunan dengan karakteristik khas yang menjadi saksi sejarah perjalanan kota Surabaya dan perlu dilestarikan. Namun, disayangkan saat ini banyak Perubahan yang terjadi pada fasade bangunan, sehingga berdampak besar pada Perubahan karakter koridor Jalan Panggung Surabaya. Oleh karena itu, penelitian ini bertujuan untuk mengetahui karakteristik fasade untuk pelestarian koridor Jalan Panggung Surabaya. Unsur fasade tersebut meliputi atap, jendela, pintu dan ornamen. Hasil penelitian ini menemukan adanya dua jenis atap, yaitu atap perisai dan atap pelana, bermaterial genteng tanah liat. Banyak bangunan yang menggunakan jendela jenis ganda dengan perletakan di sisi kanan dan kiri pintu. Pada lantai bawah, menggunakan pintu lipat kayu dan pintu jenis ganda. Pada ornamen, beberapa bangunan menggunakan listplank pada ornamen atap, ornamen konsol, jenis kolom serta balustrade bermotif kolonial dan pecinan, lubang ventilasi maupun motif bouvenlict yang beragam masih dapat ditemukan pada koridor ini. Karakteristik ini akan menjadi acuan dalam pelestarian pembangunan koridor di masa datang

Effect of spironolactone on pain responses in mice

The effects of spironolactone, a non-selective aldosterone antagonist, were examined on thermally-induced pain using the hot-plate and tail-flick tests, on hemogenic pain induced by intraplantar capsaicin, on electrically-induced pain, on visceral nociception induced by intraperitoneal acetic acid injection and on haloperidol-induced catalepsy in mice. Spironolactone significantly shortened response latency in the mouse tail-flick test but produced modest decreases in response latencies in the mouse hot plate test. The drug reduced the antinociceptive effect of tramadol in the hot plate test. Spironolactone in addition decreased nociceptive thresholds of electrically-induced pain in mice. In contrast, spironolactone elicited significant antinociceptive actions in the mouse acetic-acid-induced writhing assay and at doses of 20-160 mg/kg decreased capsaicin-induced chemogenic pain. Spironolactone at doses of 40 or 80 mg/kg reduced spontaneous activity and produced a significant impairment on the rotarod test in mice. The drug (10-80 mg/kg) increased the duration of catalepsy induced by haloperidol by 56.3-188.5 %. In conclusion, spironolactone increased pain behavior in a dosedependent manner in models of thermal and electrical pain, but decreased inflammatory visceral pain due to intraperitoneal acetic acid and chemogenic pain due to intraplantar capsaicin. The effect of spironolactone on various types of pain needs further evaluation