Pengaruh Rasio Kinerja Keuangan terhadap Tingkat Bagi Hasil Tabungan Mudharabah (pada Bank Umum Syariah yang Listing di Bank Indonesia Periode 2010-2014)

The aim of this study was to examine the Influence of CAR, ROA, ROE, NPF and BOPO On Profit Sharing of Mudharabah Savings on IslamicBank listing in BI period 2010-2014. The population in this study are all Islamic Banks in Indonesia are still in operation during the years 2010-2014 a total of 11 companies. Based on specified criteria, the company earned 11 Islamic Banks were used as samples in this study. This study uses secondary data in the form of publication of financial statements. Methods of data analysis using multiple linear regression analysis. Based on the analysis, the conclusions of this research are: 1) there is no significant effect Capital Adequacy Ratio on Profit Sharing of Mudharabah Savings in Islamic Banks with signifance value 0,163 > 0,05. 2) There is no significant effect return on assets on Profit Sharing of Mudharabah Savings in Islamic Banks with signifance value 0,070 > 0,05. 3) There is a significant effect Return On Equity on Profit Sharing of Mudharabah Savings in Islamic Banks with signifance value 0,040 < 0,05. 4) There is a significant influence NPF on Profit Sharing of Mudharabah Savings in Islamic Banks with signifance value 0,037 < 0,05. 5) There is a significant effect BOPO on Profit Sharing of Mudharabah Savings in Islamic Banks with signifance value 0,002 < 0,05. Based on the results of research on simultaneous test it was concluded that there was an effect of CAR, ROA, ROE, NPF, and BOPO together towards Profit Sharing of Mudharabah Savings in Islamic Banks

FORMULATION OF PGV-0 A NEW ANTIINFLAMMATORY AGENT AS A TABLET DOSAGE FORM

The specific objective of this study is to get the best formulation for PGV-0 as a tablet dosage form. By optimation of formulation a more potent and safe antiinflamatory drug could be obtained. This study was started with determination of physical properties which included: appearance, particle size, partition coefficient, and hygroscopicity. In the formulation of PGV-0 6 formulas were chosen with amylum and lactose as fillers, tween 80 as surfactant, solutiogelatine and solutio PVP as binding agent and talc and Mg stearate as lubricants. From these six formulas chosen physical properties of the granules and tablets were determined. PGV-0 powder was not free flowing and has bad compressibility. PGV-0 could not be proccesed by direct compression but should be formulated by wet granulation method. The best formula found was formula V which used solutio PVP 2 % as binding agent and tween 80 0,25 % as wetting agent.Key words: PGV-0, antiinflammation, formulation of tablet dosage form

Efektivitas Biaya Penggunaan Omeprazole dan Ranitidin pada Pasien Gastritis

Gastritis is an inflammation of the gastric mucosa caused by various factors such as Helicobacter pylori infection which can occure acute or chronic. The use of ranitidine therapy in gastritis patients is greater than omeprazole. The aim of the study was to analyze the cost-effectiveness of treating inpatient gastritis patients using omeprazole or ranitidine. The study was an observational cross-sectional method according to the hospital's perspective using secondary data in January-December 2016 period regarding the treatment of 65 BPJS class-III gastritis patients.The data includes demographic data, length of stay and total costs. A total of 32 patients&nbsp; class III BPJS use omeprazole and 33 patients use ranitidine. Patients age ranged from 17-65 years. Statistical used independent t-test. The results showed female (72.31%), aged 17-38 (60%) and length of stay 3-4 days (56.9%). Average total cost of omeprazole therapy Rp. 544,802.59&nbsp; and ranitidine Rp. 557,563.12, with probability 0,696 &gt; 0,05, so the result was not significantly different. Omeprazole therapy was more effective than ranitidine with percent of effectiveness 59,38% and 51,41%. ACER value of omeprazole therapy Rp. 9.234,06/1% recovery was more less than ranitidine Rp. 10.932,61/1% recovery. So omeprazole more cost-effective than ranitidine Keyword : Cost Effectiveness Analysis, gastritis, omeprazole, ranitidin

The stability of PGV-0 (Pentagamavunon-0) as an Antiinflammatory drug in liquid dosage forms

PGV-0 is a curcumin derivate, a synthetic compound which may be a candidate of a new drug. This substance has a potent inflammatory effect with a very low toxicity.One of the first step which must be searched for a candidate of drug, is to perform a stability study. There are many degraded drugs causing the adverse reactions. Most of them could be the initiator in forming an antigen at anaphylactic reaction or allergic reaction. Further more some of the degraded drugs are very toxic. So, the study of degradation or the stability investigations of a new drug should be carried out.The PGV-0 stability in a buffer solution at pH 10,0 had been studied by an accelerated temperature method. The temperatures were held at 50°, 55° and 60° C. The intact PGV-0 has been analysed by HPLC. The results then were used to define the shelf-life, the half life and the activation energy of the degradation of PGV-0.It was evident that PGV-0 was unstable in aqueous solution, the shelf-life was only 45.3 hours, the half-life was 299 hours and the activation energy was 14,2 kkal mol-1. Because the PGV-0 was not stable in aqueous solution, it is suggested that this substance should be made into solid dosage forms instead of the liquid dosage forms.Key word : PGV-0, stability, solutio

Effect of Rhizopus azygosporus UICC 539 growth on the nutrient content of sterile slurry and palm kernel cake mixtures at different temperature

Abstract This study reported the effect of Rhizopus azygosporus UICC 539 growth on the sterile slurry and palm kernel cake (PKC), and analysis of the nutrient content of the waste mixtures. The fungus showed good growth on Potato Sucrose Agar (PSA) at temperature range of 30 to 50 °C, and could not grow at 55 °C. Inoculum was prepared from fungal culture in Potato Sucrose Broth (PSB) by still fermentation at 30 and 40 °C for 5 days. Sterile slurry and PKC (3:1) in Petri dishes (diameter 9 cm) were prepared and solid-state fermentation was carried out using inoculum (10 %, v/v) at 30 and 40 °C, and incubated for 5 days. Rhizopus azygosporus UICC 539 showed good growth and increased cell numbers on sterile waste mixtures. Effect of fungal growth on the nutrient content of the waste mixtures was observed by comparing the treatment and control. There was an increase in the moisture and ash content, and a decrease in protein content, total calorie and carbohydrate content. There was no change of the calorie from fat and total fat content compared to the control.</jats:p

Solid-state fermentation of sterile slurry and palm kernel cake (PKC) mixture using Rhizopus azygosporus UICC 539

Abstract This study described solid-state fermentation of sterile slurry and palm kernel cake (PKC) mixtures by Rhizopus azygosporus UICC 539, preparation of the fungus and waste mixture as a formula for animal feed, and analysis of nutrient content of the formula. Preparation of inoculum (v/v) in Potato Sucrose Broth (PSB) was carried out at 30 and 40 °C for 5 days. Wet weight biomass was used as inoculum for solid-state fermentation (SSF) using sterile slurry and PKC (3:1) mixtures and SSF was carried out in flat trays (20×20×5 cm) at 30 and 40 °C for 5 days. The fermented waste mixture was dried at 60 °C for 5 days. Changes in nutrient content of the formula were observed by comparing the treatment and control. Formula prepared at 30 °C showed an increase in carbohydrate, protein and moisture content. A decrease was observed in total fat and ash content, calorie from fat and total calorie. Formula prepared at 40 °C showed an increase in protein and ash content. A decrease was observed in carbohydrate, moisture and total fat content, calorie from fat, and total calorie. Rhizopus azygosporus UICC 539 was able to grow and utilize the palm oil processing waste and improved the nutrient content of the formula.</jats:p

Solid-state fermentation and formulation of non-sterile palm oil processing waste using Rhizopus azygosporus UICC 539

Abstract This study reported the ability of Rhizopus azygosporus UICC 539 to utilize non-sterile slurry and palm kernel cake (PKC) through solid-state fermentation, preparation of the fungus and non-sterile waste mixture as a formula for animal feed, and analysis of nutrient content of the formula. Fungal culture in PSB at 30 and 40 °C for 5 days was prepared and wet weight biomass was used as inoculum for animal feed formula. Solid-state fermentation (SSF) was carried out on the mixtures of non-sterile slurry and PKC (3:1) at 30 and 40 °C for 5 days and the fermented waste mixtures were dried at 60°C for 5 days. The results showed that during SSF there were presence of colonies of other fungi and bacteria from the waste mixture besides R. azygosporus. The total cell number of R. azygosporus and other fungi were decreased after SSF. Changes in nutrient content in the formula were observed by comparing the treatment and control. Formula prepared at 40 °C showed an increase of carbohydrate content and total calorie, while formula prepared at 30 °C showed an increase only at carbohydrate content. A decrease of protein, water content, ash content, total fat, and energy from fat, was observed in formulas prepared at both temperatures.</jats:p