A Correlation Between Hard Gamma-ray Sources and Cosmic Voids Along the Line of Sight

We estimate the galaxy density along lines of sight to hard extragalactic gamma-ray sources by correlating source positions on the sky with a void catalog based on the Sloan Digital Sky Survey (SDSS). Extragalactic gamma-ray sources that are detected at very high energy (VHE; E>100 GeV) or have been highlighted as VHE-emitting candidates in the Fermi Large Area Telescope hard source catalog (together referred to as "VHE-like" sources) are distributed along underdense lines of sight at the 2.4 sigma level. There is also a less suggestive correlation for the Fermi hard source population (1.7 sigma). A correlation between 10-500 GeV flux and underdense fraction along the line of sight for VHE-like and Fermi hard sources is found at 2.4 sigma and 2.6 sigma, respectively. The preference for underdense sight lines is not displayed by gamma-ray emitting galaxies within the second Fermi catalog, containing sources detected above 100 MeV, or the SDSS DR7 quasar catalog. We investigate whether this marginal correlation might be a result of lower extragalactic background light (EBL) photon density within the underdense regions and find that, even in the most extreme case of a entirely underdense sight line, the EBL photon density is only 2% less than the nominal EBL density. Translating this into gamma-ray attenuation along the line of sight for a highly attenuated source with opacity tau(E,z) ~5, we estimate that the attentuation of gamma-rays decreases no more than 10%. This decrease, although non-neglible, is unable to account for the apparent hard source correlation with underdense lines of sight.Comment: Accepted by MNRA

Melting in Martian Snowbanks

Precipitation as snow is an emerging paradigm for understanding water flow on Mars, which gracefully resolves many outstanding uncertainties in climatic and geomorphic interpretation. Snowfall does not require a powerful global greenhouse to effect global precipitation. It has long been assumed that global average temperatures greater than 273K are required to sustain liquid water at the surface via rainfall and runoff. Unfortunately, the best greenhouse models to date predict global mean surface temperatures early in Mars' history that differ little from today's, unless exceptional conditions are invoked. Snowfall however, can occur at temperatures less than 273K; all that is required is saturation of the atmosphere. At global temperatures lower than 273K, H2O would have been injected into the atmosphere by impacts and volcanic eruptions during the Noachian, and by obliquity-driven climate oscillations more recently. Snow cover can accumulate for a considerable period, and be available for melting during local spring and summer, unless sublimation rates are sufficient to remove the entire snowpack. We decided to explore the physics that controls the melting of snow in the high-latitude regions of Mars to understand the frequency and drainage of snowmelt in the high martian latitudes

Urine metabolomic analysis to detect metabolites associated with the development of contrast induced nephropathy.

ObjectiveContrast induced nephropathy (CIN) is a result of injury to the proximal tubules. The incidence of CIN is around 11% for imaging done in the acute care setting. We aim to analyze the metabolic patterns in the urine, before and after dosing with intravenous contrast for computed tomography (CT) imaging of the chest, to determine if metabolomic changes exist in patients who develop CIN.MethodsA convenience sample of high risk patients undergoing a chest CT with intravenous contrast were eligible for enrollment. Urine samples were collected prior to imaging and 4 to 6 hours post imaging. Samples underwent gas chromatography/mass spectrometry profiling. Peak metabolite values were measured and data was log transformed. Significance analysis of microarrays and partial least squares was used to determine the most significant metabolites prior to CT imaging and within subject. Analysis of variance was used to rank metabolites associated with temporal change and CIN. CIN was defined as an increase in serum creatinine level of ≥ 0.5 mg/dL or ≥ 25% above baseline within 48 hours after contrast administration.ResultsWe sampled paired urine samples from 63 subjects. The incidence of CIN was 6/63 (9.5%). Patients without CIN had elevated urinary citric acid and taurine concentrations in the pre-CT urine. Xylulose increased in the post CT sample in patients who developed CIN.ConclusionDifferences in metabolomics patterns in patients who do and do not develop CIN exist. Metabolites may be potential early identifiers of CIN and identify patients at high-risk for developing this condition prior to imaging

A high-reflectivity, ambient-stable graphene mirror for neutral atomic and molecular beams

The following article appeared in Applied Physics Letters Volume 99, Issue 21, 21 November 2011, Article number 211907 and may be found at http://scitation.aip.org/content/aip/journal/apl/99/21/10.1063/1.3663866We report a He and H2 diffraction study of graphene-terminated Ru(0001) thin films grown epitaxially on c-axis sapphire. Even for samples exposed for several weeks to ambient conditions, brief annealing in ultrahigh vacuum restored extraordinarily high specular reflectivities for He and H 2 beams (23 and 7 of the incident beam, respectively). The quality of the angular distributions recorded with both probes exceeds the one obtained from in-situ prepared graphene on Ru(0001) single crystals. Our results for graphene-terminated Ru thin films represent a significant step toward ambient tolerant, high-reflectivity curved surface mirrors for He-atom microscopyWork performed in part at the Center for Functional Nanomaterials, Brookhaven National Laboratory, which issupported by the U.S. Department of Energy, Office of Basic Energy Sciences, under Contract No. DE-AC02-98CH10886. Work supported by the Ministerio de Educacion y Ciencia through projects CONSOLIDER-INGENIO 2010 on Molecular Nanoscience (CSD 2007-00010), FIS2010-18847, and byComunidad de Madrid through the program NANOBIOMAGNET (S2009/MAT-1726)

Atom clusters and vibrational excitations in chemically-disordered Pt357Fe

Inelastic nuclear resonant scattering spectra of Fe-57 atoms were measured on crystalline alloys of Pt3Fe-57 that were chemically disordered, partially ordered, and L1(2) ordered. Phonon partial density of states curves for Fe-57 were obtained from these spectra. Upon disordering, about 10% of the spectral intensity underwent a distinct shift from 25 to 19 meV. This change in optical modes accounted for most of the change of the vibrational entropy of disordering contributed by Fe atoms, which was (+0.10 +/- 0.03) k(B) (Fe atom)(-1). Prospects for parametrizing the vibrational entropy with low-order cluster variables were assessed. To calculate the difference in vibrational entropy of the disordered and ordered alloys, the clusters must be large enough to account for the abundances of several of the atom configurations of the first-nearest-neighbor shell about the Fe-57 atoms

Correlation of pre-operative cancer imaging techniques with post-operative gross and microscopic pathology images

In this paper, different algorithms for volume reconstruction from tomographic cross-sectional pathology slices are described and tested. A tissue-mimicking phantom made with a mixture of agar and aluminium oxide was sliced at different thickness as per pathological standard guidelines. Phantom model was also virtually sliced and reconstructed in software. Results showed that shape-based spline interpolation method was the most precise, but generated a volume underestimation of 0.5%

Prepyramid-to-pyramid transition of SiGe islands on Si(001)

The morphology of the first three-dimensional islands appearing during strained growth of SiGe alloys on Si(001) was investigated by scanning tunneling microscopy. High resolution images of individual islands and a statistical analysis of island shapes were used to reconstruct the evolution of the island shape as a function of size. As they grow, islands undergo a transition from completely unfacetted rough mounds (prepyramids) to partially {105} facetted islands and then they gradually evolve to {105} facetted pyramids. The results are in good agreement with the predictions of a recently proposed theoretical model