Atypical Christmas Eye Disease: A Case Report and Literature Review

Background: Christmas Eye Disease (CED), also known as the “Albury-Wodonga syndrome” or “Harvester's Keratitis”, is a seasonal acute corneal ulceration syndrome, which is geographically limited to Australia, specifically in the south-west region of New South Wales (NSW) and north-east region of Victoria. The mechanism of injury is unknown, but the secretions from native beetles of the genus Orthoperus have been implicated. There remains a dearth of literature on CED, particularly with atypical disease presentations. We present the first reported case of CED in the upper Blue Mountains Region, presenting atypically with mild pain and foreign body sensation. We also aim to explore the possible entomological precipitants of the disease. Case Presentation: A 77-year-old man with a 1-day history of a mildly painful red eye was found to have acute corneal ulceration. He experienced mild discomfort in his right eye while asleep and woke the following morning with persistent blur, foreign body sensation, and photophobia. He had no history of ocular trauma or chemical exposure. He reported going for daily bushwalks in the upper Blue Mountains region but did not recall any exposure to environmental or entomological precipitants. Clinical Findings and Outcomes: Slit-lamp examination revealed a substantial corneal epithelial loss in the right eye with fluorescein staining, revealing a characteristic ‘green splash’ over 90% of the cornea. Other clinical findings included marked corneal edema, moderate conjunctival injection, mild palpebral swelling, and mild papillae. No anterior uveitis was observed, and the posterior segment examination was normal. There was a considerable reduction in his right visual acuity from baseline. He was empirically treated with 1% tropicamide ocular drops, 1% chloramphenicol ointment, and lubricant ocular drops. The bacterial and viral conjunctival swabs were unremarkable. Clinical progression was self-limiting, and complete resolution of the ulcer was achieved after one month. Conclusion: CED is a clinical diagnosis, and medical practitioners should be aware of atypical features, such as the absence of debilitating pain. Additionally, our case demonstrates that the geographic distribution of CED appears to be far more extensive than previously thought, thereby raising the possibility of disease manifestation in regions not commonly associated with it. Entomological precipitants of this condition remain circumstantial and warrant further validation. </jats:sec

Acute Unilateral Central Serous Chorioretinopathy after Immunization with Pfizer-BioNTech COVID-19 Vaccine: A Case Report and Literature Review.

INTRODUCTION: A 43-year-old Caucasian male presented to our ophthalmology clinic with blurry vision and metamorphopsia in his right eye, 24 hours after receiving the first dose of the Pfizer-BioNTech COVID-19 vaccine. METHODS: Clinical examination and imaging tests were consistent with acute unilateral central serous chorioretinopathy (CSCR) that completely resolved after 2 months without any treatment. He had no significant ophthalmic or medical history. He also lacked the classical risk factors for CSCR such as recent psychosocial stressors, Type-A personality traits, history of exogenous steroid use, connective tissue disorders and obstructive sleep apnea. RESULTS: This appears to be only the second reported case of CSCR, temporally associated with a recombinant COVID-19 mRNA vaccine. We also present a summary of published reports demonstrating intraocular complications associated with the novel recombinant COVID-19 mRNA vaccines. CONCLUSION: Findings in this report should not deter COVID-19 vaccinations given the rarity of aforementioned ocular complications and the greater benefit of protection from COVID-19 infection. Medical practitioners, however, should remain mindful of potential ocular complications, given the greater likelihood of occurrence with increasing vaccination booster rates

Allelopathic Plants. 7. Sunflower (Helianthus annuus L.)

Sunflower is an annual dicotyledonous plant, herbaceous, erect and native of North America. It is thermo- and photo-insensitive, hence, can be grown round the year in sub-tropical and tropical countries. Only two spp. H. annuus and H. tuberosum are cultivated for food, remaining spp. are ornamentals, weeds and wild plants. However, H. annuus is allelopathic and inhibit the growth and development of other plants thus reducing their productivity. Much information is available about the allelopathic effects of sunflower crop on following crops in crop rotations. Although it is harmful to all crops, but, is less harmful to crops of Graminae family than other families. It seems that the harmful effects of sunflower in crop rotations are due to release and accumulation of root exudates during crop growth in soil. Soil incorporation of its fresh (green manure) or dry biomass in soil is inhibitory to both crops and weed spp. Several allelochemicals have been characterized from the H. annuus, which inhibit the seed germination and seedling growth of A. albus, A. viridis, Agropyron repens (Elymus repens), Ambrosia artemsiifolia, Avena fatua, Celosia crustata, Chenopodium album, Chloris barbara, Cynodon dactylon, D. sanguinalis, Dactyloctenium ageyptium, Digitaria ciliaris, Echinochloa crus-galli, Flaveria australasica, Parthenium hysterophorus, Portulaca oleracea, Sida spinosa, Trianthema portulacastrum, Veronica perisca. The inhibitory effects of this crop may be used for weed management with less herbicides for sustainable agriculture.Depto. de Biol. Apl. a Agropecuaria Universidade Estadual Paulista, Via Acesso Prof. P. D. Castellane, CEP 14884-900. Jaboticabal, SPDepartment of Agronomy Haryana Agricultural University, Hisar-125 004Depto. de Biol. Apl. a Agropecuaria Universidade Estadual Paulista, Via Acesso Prof. P. D. Castellane, CEP 14884-900. Jaboticabal, S

Towards a new method of porosimetry: principles and experiments

Current experimental methods used to determine pore size distributions (PSD) of porous media present several drawbacks such as toxicity of the employed fluids (e.g., mercury porosimetry). The theoretical basis of a new method to obtain the PSD by injecting yield stress fluids through porous media and measuring the flow rate Q at several pressure gradients ∇P was proposed in the literature. On the basis of these theoretical considerations, an intuitive approach to obtain PSD from Q(∇P) is presented in this work. It relies on considering the extra increment of Q when ∇P is increased, as a consequence of the pores of smaller radius newly incorporated to the flow. This procedure is first tested and validated on numerically generated experiments. Then, it is applied to exploit data coming from laboratory experiments and the obtained PSD showgood agreement with the PSD deduced frommercury porosimetry