Anharmonic phonon spectra of PbTe and SnTe in the self-consistent harmonic approximation

At room temperature, PbTe and SnTe are efficient thermoelectrics with a cubic structure. At low temperature, SnTe undergoes a ferroelectric transition with a critical temperature strongly dependent on the hole concentration, while PbTe is an incipient ferroelectric. By using the stochastic self-consistent harmonic approximation, we investigate the anharmonic phonon spectra and the occurrence of a ferroelectric transition in both systems. We find that vibrational spectra strongly depends on the approximation used for the exchange-correlation kernel in density functional theory. If gradient corrections and the theoretical volume are employed, then the calculation of the free energy Hessian leads to phonon spectra in good agreement with experimental data for both systems. In PbTe, we reproduce the transverse optical mode phonon satellite detected in inelastic neutron scattering and the crossing between the transverse optical and the longitudinal acoustic modes along the $\Gamma$X direction. In the case of SnTe, we describe the occurrence of a ferroelectric transition from the high temperature Fm$\overline{3}$m structure to the low temperature R3m one.Comment: 12 pages, 15 Picture

Coalition Resilient Outcomes in Max k-Cut Games

We investigate strong Nash equilibria in the \emph{max $k$-cut game}, where we are given an undirected edge-weighted graph together with a set $\{1,\ldots, k\}$ of $k$ colors. Nodes represent players and edges capture their mutual interests. The strategy set of each player $v$ consists of the $k$ colors. When players select a color they induce a $k$-coloring or simply a coloring. Given a coloring, the \emph{utility} (or \emph{payoff}) of a player $u$ is the sum of the weights of the edges $\{u,v\}$ incident to $u$, such that the color chosen by $u$ is different from the one chosen by $v$. Such games form some of the basic payoff structures in game theory, model lots of real-world scenarios with selfish agents and extend or are related to several fundamental classes of games. Very little is known about the existence of strong equilibria in max $k$-cut games. In this paper we make some steps forward in the comprehension of it. We first show that improving deviations performed by minimal coalitions can cycle, and thus answering negatively the open problem proposed in \cite{DBLP:conf/tamc/GourvesM10}. Next, we turn our attention to unweighted graphs. We first show that any optimal coloring is a 5-SE in this case. Then, we introduce $x$-local strong equilibria, namely colorings that are resilient to deviations by coalitions such that the maximum distance between every pair of nodes in the coalition is at most $x$. We prove that $1$-local strong equilibria always exist. Finally, we show the existence of strong Nash equilibria in several interesting specific scenarios.Comment: A preliminary version of this paper will appear in the proceedings of the 45th International Conference on Current Trends in Theory and Practice of Computer Science (SOFSEM'19

Signals and Power Distribution in the CMS Inner Tracker

\begin{abstract} This Note describes how the interconnection between the 3540 modules of the CMS Inner Tracker has been approached, focusing on the signal, high voltage and low voltage line distribution. The construction and tests of roughly a thousand interconnects called ``Mother Cables" is described. \end{abstract

Conversion of the Mycotoxin Patulin to the Less Toxic Desoxypatulinic Acid by the Biocontrol Yeast Rhodosporidium kratochvilovae Strain LS11

Se describe en este artículo el descubrimiento de la degradación de la micotoxina patulina por una levaduraThe infection of stored apples by the fungus Penicillium expansum causes the contamination of fruits and fruit-derived products with the mycotoxin patulin, which is a major issue in food safety. Fungal attack can be prevented by beneficial microorganisms, so-called biocontrol agents. Previous time-course thin layer chromatography analyses showed that the aerobic incubation of patulin with the biocontrol yeast Rhodosporidium kratochvilovae strain LS11 leads to the disappearance of the mycotoxin spot and the parallel emergence of two new spots, one of which disappears over time. In this work, we analyzed the biodegradation of patulin effected by LS11 through HPLC. The more stable of the two compounds was purified and characterized by nuclear magnetic resonance as desoxypatulinic acid, whose formation was also quantitated in patulin degradation experiments. After R. kratochvilovae LS11 had been incubated in the presence of 13C-labeled patulin, label was traced to desoxypatulinic acid, thus proving that this compound derives from the metabolization of patulin by the yeast. Desoxypatulinic acid was much less toxic than patulin to human lymphocytes and, in contrast to patulin, did not react in vitro with the thiol-bearing tripeptide glutathione. The lower toxicity of desoxypatulinic acid is proposed to be a consequence of the hydrolysis of the lactone ring and the loss of functional groups that react with thiol groups. The formation of desoxypatulinic acid from patulin represents a novel biodegradation pathway that is also a detoxification process

Hip viscosupplementation under ultra-sound guidance riduces NSAID consumption in symptomatic hip osteoarthritis patients in a long follow-up. Data from Italian registry.

Introduction: Non-steroidal anti-inflammatory drugs (NSAIDs) consumption is strictly related to a high gastrointestinal and cardiovascular mortality and morbidity rate. Osteoarthritis Research Society International (OARSI) recommendations in patients with symptomatic hip or knee OA stated that NSAIDs should be used at the lowest effective dose but their long-term use should be avoided if possible. OARSI guidelines for the treatment of the hip OA include the use of viscosupplementation, which aims to restore physiological and Theological features of the synovial fluid. Objective: Aim of this multicentric, open and retrospective study is to investigate if NSAID consumption may be reduced by the use of ultrasound-guided intra-articular injection of several hyaluronic acid (HA) products in hip joint administered in patients affected by symptomatic hip OA. Materials and Methods: Patients affected by mono or bilateral symptomatic hip OA according to American Rheumatology Association (ARA) criteria, radiological OA graded II-IV (Kellgren and Lawrence) entered the study and were administered with ultrasound-guided intra-articular injection of hyaluronic acid products. As a primary endpoint, consumption of NSAIDs was evaluated by recording the number of days a month (range 0-30) the patient had used NSAID during the previous month, reported at each visit during the 24 months follow-up period. Secondary endpoints included further analysis for subgroups of patients categorized for Lequesne index score, Kellgren-Lawrence score, pain visual analogue scale (VAS) score, ultrasound pattern, age, hyaluronic acid used. Results: 2343 patients entered the study. Regarding primary endpoint, the consumption of NSAIDs was reduced of 48.2% at the third month when compared with baseline values. This sparing effect increased at 12th and 24th month with a reduction respectively of 50% and 61% in comparison to baseline values. These differences were statistically significant. Conclusions: These data point out that intraarticular hyaluronan preparations provide OA pain relief and reduce NSAIDs consumption in a large cohort of patients for a long period of follow-up. Multiple courses of viscosupplementation (vs) are required to maintain low dose of NSAID consumption over time. NSAIDs consumption is strictly related to an high gastrointestinal and cardiovascular mortality and morbidity rate, instead HA intra-articular treatment is well tolerated and is associated with a low incidence of adverse effects. For these reasons further studies evaluating cost-effectiveness and cost-utility of VS in the management of hip OA are required

The Mitochondrial Ca(2+) Uniporter: Structure, Function, and Pharmacology.

Mitochondrial Ca(2+) uptake is crucial for an array of cellular functions while an imbalance can elicit cell death. In this chapter, we briefly reviewed the various modes of mitochondrial Ca(2+) uptake and our current understanding of mitochondrial Ca(2+) homeostasis in regards to cell physiology and pathophysiology. Further, this chapter focuses on the molecular identities, intracellular regulators as well as the pharmacology of mitochondrial Ca(2+) uniporter complex

Integration of biocontrol agents and food-grade additives for enhancing protection of stored apples from Penicillium expansum.

Forty-nine compounds currently used as additives in foods were tested in combination with three biocontrol agents, the yeasts Rhodotorula glutinis, Cryptococcus laurentii, and the yeastlike fungus Aureobasidium pullulans, to increase their antagonistic activity against Penicillium expansum, the causal agent of blue mold on apples. Twelve additives dramatically improved the antagonistic activity of one or more of the tested biocontrol agents. In a two-way factorial experiment with these selected additives the percentage of P. expansum rots on apples was significantly influenced by the antagonist and the additive as well as by their interaction. The combination of the biocontrol agents and some additives resulted in a significantly higher activity with respect to the single treatments applied separately, producing additive or synergistic effects. Some of the selected additives combined with a low yeast concentration (106 cells per ml) had comparable or higher efficacy than the biocontrol agents applied alone at a 100-fold higher concentration (10(8) cells per ml). Some organic and inorganic calcium salts, natural gums, and some antioxidants displayed the best results. In general, the effect of each additive was specific to the biocontrol isolate used in the experiments. Possible mechanisms involved in the activity of these beneficial additives and their potential application in effective formulations of postharvest biofungicides are discussed

Transit-Oriented Development in Middle Eastern Cities: The Urban Renewal Framework for the SouqWaqif in Doha, Qatar

The article examines the impact of rapid urbanization and economic growth on transportation-related challenges in Qatar, particularly in the Souq Waqif neighborhood of Doha. These issues include urban sprawl, traffic congestion, poor walkability, and a lack of pedestrian accessibility and connectivity. The study focuses on the Souq Waqif metro station, analyzing its performance in five key design areas: walkability, ground use balance, mixed-use and public spaces, multimodality and transportation hubs, and the public transportation network. Using the Integrated Modification Methodology (IMM), the research aims to transform underperforming areas into sustainable communities through retrofitting and renovation. Data collection involved site observations, interviews, and surveys. The findings reveal significant deficiencies in connectivity and multimodal transportation around Souq Waqif station. Additionally, the study explores how metro stations in rapidly growing cities like Doha can preserve cultural heritage and social identity. The article offers recommendations to improve the efficiency and sustainability of Souq Waqif and similar urban spaces