Pengobatan Malaria Kombinasi Artemisinin (ACT) Di Provinsi Papua Barat Tahun 2013

Malaria is still a disease with highest incidence rate in Indonesias. Based on Riskesdas 2013, the prevalence of malaria in West Papua was generally increasing. This study aimed to find the correlation of type of malaria found in blood examination and distribution status of ACT. Samples of data obtained by stratified random sampling from 1490 people who had suffered from malaria in West Papua. Data analysis using univariate descriptive and correlation analysis The result showed that the most common type of malaria was tertiana malaria caused by Plasmodium vivax (51%). Early detection performed within the first 24 hours when the patient is suffering from fever can be used as the basis for a policy that early detection can reduce malaria morbidity. It can be concluded ACT suitable for any type of malaria. The concistency of provision of ACT can be implemented by increasing public awareness of taking prophylactic. In addition the ideal combination antimalarial drugs be able to heal in a short time and if the patients performs the compliance of taking the drug, it will not be antimalarial resistance.Malaria merupakan penyakit dengan angka kesakitan tinggi di Indonesia. Data Riskesdas 2013 menunjukkan prevalensi malaria di Papua Barat meningkat. Tujuan penelitian untuk mencari hubungan antara jenis malaria yang ditemukan dalam pemeriksan darah dengan status pemberian obat antimalaria ACT (Artemisinin-based Combination Therapy). Pengambilan sampel secara stratified random sampling dan diperoleh 1490 penduduk yang seluruhnya dikonfirmasi menderita malaria dari populasi penduduk di Provinsi Papua Barat. Analisis data menggunakan analisis deskriptif univariat dan analisis korelasi. Hasil penelitian menunjukkan bahwa jenis malaria yang paling banyak ditemukan adalah malaria tertiana yang disebabkan oleh Plasmodium vivax (51%). Deteksi dini yang dilakukan dalam 24 jam pertama saat penderita mengalami demam dapat dijadikan dasar untuk mengambil kebijakan bahwa deteksi dini mampu mengurangi angka kesakitan malaria. Pemberian obat antimalaria tidak tergantung pada jenis malaria yang diderita. ACT sesuai untuk jenis malaria apa saja. Konsistensi pemberian ACT diperoleh dengan cara meningkatkan kesadaran masyarakat untuk mengonsumsi obat profilaksis. Selain itu obat antimalaria kombinasi yang ideal mampu menyembuhkan dalam waktu yang singkat dan jika penderita melaksanakan kepatuhan mengonsumsi obat maka tidak akan terjadi resistensi terhadap antimalaria

Potensi Birdwatching sebagai Salah Satu Daya Tarik Wisata di Desa Wisata Jatimulyo, Kecamatan Girimulyo,kabupaten Kulon Progo

This study aims to identify the response of tourists in Jatimulyo Tourism Village towards the plan of developing birdwatching tourism. Birds have a strong attractiveness for certain groups of people, such as bird hobbies due to their diverse characteristics which have a high selling value. Jatimulyo Tourism Village is one of the tourism villages known for its bird diversity. Regarding that situation, the Jatimulyo government issued a Village Regulation (so-called Peraturan Desa or PerDes) about prohibition of hunting activities. It was already applied by sanctioning wild-life hunters, including bird hunter. However, the application of PerDes was not strong enough to protect the bird diversity. Thus, there must be alternatives program by utilizing the bird diversity to give economic advantages for the people. Birdwatching tourism is one of the alternatives and there is possibility to develop it in this village, considering this village has already been recognized as tourism village. This research was a quantitative research and employing survey with questionnaire as the instrument. There were 100 questionnaires given to the tourists in Jatimulyo Tourism Village to gather valid data. The term of birdwatching is still a foreign term for the people. The observation results show that most of the tourists had ever heard the term but did not know its meaning. However, most of the tourists were agreed with the alternative of developing this tourism village with birdwatching as one of the attractions but in one condition i.e. the tour package was not more than one day with affordable budget. They also wanted bird observation and photography as the activities of birdwatching. Furthermore, they needed professional guide to guide them along the tour. Keywords : birdwatching, avitourism, tourism, tourism villag

Pendidikan Media Literacy pada Siswa/siswi SMPN 10 Padang

Dewasa ini, internet telah tumbuh menjadi sedemikian besar dan berdaya sebagai alat informasi dan komunikasi yang tak dapat diabaikan. Penggunanya kini mencakup berbagai kalangan. Perkembangan teknologi komunikasi dan cyber media sudah selayaknya diimbangi dengan kemampuan melek bermedia masyarakat, termasuk anak-anak yang merupakan konsumen aktif dunia maya. Kegiatan pengabdian masyarakat ini dilatar belakangi oleh masih kurangnya kemampuan melek media internet pada masyarakat di Sumatera Barat terutama bagi siswa siswi SMP yang saat ini rata-rata sudah sangat aktif mengkonsumsi media sosial dengan tujuan memberikan edukasi untuk bisa bijaksana dalam menggunakan internet. Sasaran utama dalam kegiatan ini adalah siswa-siswi SMPN 10 Padang dengan jumlah peserta sebanyak 30 orang. Metode kegiatan dilakukan secara sistematis yaitu dengan berupa presentasi, diskusi kelompok, tanya jawab dan evaluasi dalam bentuk kuis/games. Kegiatan pengabdian masyarakat di SMPN 10 Padang ini telah berjalan dengan lancar dan sesuai dengan rencana yang ditetapkan. Hasil kegiatan ini pengabdian ini menunjukkan bahwa anak-anak peserta kegiatan mulai memahami bahwa bahaya internet tidak hanya sebatas bahaya fisik tetapi juga sampai pada bahaya keamanan psikologis dan bahkan hukum, sehingga mereka berjanji untuk lebih bijak menggunakan internet ke depannya. Artinya, peserta sudah berhasil memahami apa itu literasi media dan bagaimana cara menggunakan media dengan lebih bijak. Kata Kunci: Pendidikan, Literasi media, Ana

STRATEGI PEMASARAN TANAMAN HIAS PADA CV. DIAN PURNAMA DI KOTA PALANGKA RAYA

Penelitian ini bertujuan untuk : 1). Mengetahui faktor-faktor apa saja yang terdapat dalam lingkungan internal dan eksternal pemasaran tanaman hias usaha CV. Dian Purnama. 2). Menentukan strategi pemasaran yang tepat pada usaha CV. Dian Purnama. Penelitian ini merupakan penelitian kuantitatif dan kualitatif. Penelitian dilaksanakan di Jl. Yos Sudarso No.66 Kecamatan Jekan Raya Kelurahan Menteng Kota Palangka Raya yang dilakukan selama 1 tahun terhitung dari April 2021 hingga Maret 2022. Jenis dan sumber data yang dipakai dalam penelitian ini yaitu data primer dan data sekunder. Metode pengumpulan data dengan cara observasi, wawancara, dan memberikan kuisioner. Hasil penelitian menunjukan bahwa posisi usaha CV. Dian Purnama pada kuadran SWOT berada pada kuadran 1 (0,689 : 0,813), artinya posisi usaha tersebut pada situasi yang sangat menguntungkan. Perusahaan tersebut memiliki peluang dan kekuatan sehingga dapat memanfaatkan peluang yang ada. Strategi yang harus diterapkan dalam kondisi ini adalah mendukung kebijakan pertumbuhan yang agresif (growth oriented strategy). The objectives of this research are : 1). Knowing what factors are contained in the internal and external environment of CV. Dian Purnama's ornamental plant marketing business. 2). Determine the right marketing strategy for CV. Dian Purnama's business. This research is a quantitative and qualitative research. The research was conducted on Jl. Yos Sudarso No.66 Jekan Raya District, Menteng Village, Palangka Raya City, which was carried out for 1 year from April 2021 to March 2022. The types and sources of data used in this study were primary data and secondary data. Methods of collecting data by means of observation, interviews, and questionnaires. The results showed that CV Dian Purnama's business position in the SWOT quadrant was in quadrant 1 (0.689: 0.813), meaning that the business position was in a very profitable situation. The company has opportunities and strengths so that it can take advantage of existing opportunities. The strategy that must be applied in this condition is to support aggressive growth (growth oriented strategy)

Adaptation responses to climate change differ between global megacities

Urban areas are increasingly at risk from climate change, with negative impacts predicted for human health, the economy and ecosystems1, 2. These risks require responses from cities to improve their resilience. Policymakers need to understand current adaptation spend to plan comprehensively and effectively. Through the measurement of spend in the newly defined ‘adaptation economy’, we analyse current climate change adaptation efforts in ten megacities. In all cases, the adaptation economy remains a small part of the overall economy, representing a maximum of 0.33% of a city’s gross domestic product (here referred to as GDPc). Differences in total spend are significant between cities in developed, emerging and developing countries, ranging from £15 million to £1,600 million. Comparing key subsectors, we demonstrate the differences in adaptation profiles. Developing cities have higher proportional spend on health and agriculture, whereas developed cities have higher spend on energy and water. Spend per capita and percentage of GDPc comparisons more clearly show disparities between cities. Developing country cities spend half the proportion of GDPc and significantly less per capita, suggesting that adaptation spend is driven by wealth rather than the number of vulnerable people. This indicates that current adaptation activities are insufficient in major population centres in developing and emerging economies

Regulation of Transcriptional Activators by DNA-Binding Domain Ubiquitination

Ubiquitin is a key component of the regulatory network that maintains gene expression in eukaryotes, yet the molecular mechanism(s) by which non-degradative ubiquitination modulates transcriptional activator (TA) function is unknown. Here endogenous p53, a stress-activated transcription factor required to maintain health, is stably monoubiquitinated, following pathway activation by IR or Nutlin-3 and localized to the nucleus where it becomes tightly associated with chromatin. Comparative structure–function analysis and in silico modelling demonstrate a direct role for DNA-binding domain (DBD) monoubiquitination in TA activation. When attached to the DBD of either p53, or a second TA IRF-1, ubiquitin is orientated towards, and makes contact with, the DNA. The contact is made between a predominantly cationic surface on ubiquitin and the anionic DNA. Our data demonstrate an unexpected role for ubiquitin in the mechanism of TA-activity enhancement and provides insight into a new level of transcriptional regulation

Focus on environmental risks and migration: causes and consequences

Environmental change poses risks to societies, including disrupting social and economic systems such as migration. At the same time, migration is an effective adaptation to environmental and other risks. We review novel science on interactions between migration, environmental risks and climate change. We highlight emergent findings, including how dominant flows of rural to urban migration mean that populations are exposed to new risks within destination areas and the requirement for urban sustainability. We highlight the issue of lack of mobility as a major issue limiting the effectiveness of migration as an adaptation strategy and leading to potentially trapped populations. The paper presents scenarios of future migration that show both displacement and trapped populations over the incoming decades. Papers in the special issue bring new insights from demography, human geography, political science and environmental science to this emerging field

Potensi Kompos Kombinasi Eceng Gondok (Eichhornia crassipes) dan Azolla (Azolla sp.) sebagai Pupuk pada Pertanian Organik

Hakim F, Ramadhanti BQ, Wafi IH, Yulinda RA, Melisanti R, Shafiyah S, Sulaiman F. 2021. Potential of combination of water hyacinth (Eichhornia Crassipes) and Azolla (Azolla sp.) as Fertilizer in Organic Agriculture. In: Herlinda S et al. (Eds), Prosiding Seminar Nasional Lahan Suboptimal Ke-9 Tahun 2021, Palembang 20 oktober 2021. pp. 587-594.  Palembang: penerbit  dan percetakan Universitas Sriwijaya (UNSRI). The purpose of this literature study was to examine whether the addition of azolla to water hyacinth compost has the potential to increase N nutrients in water hyacinth compost. The methodology was carried out by reviewing research results from various scientific journal literature. The result, that the nutrient content of water hyacinth compost has a total N element of 1.3%, while according to other studies, the total N nutrient content in water hyacinth compost is (1.58-1.75%), then Azolla plants have a total N content of 2.77% while in other studies showed that the total N content of azolla was 2.57%. The conclusion, combining water hyacinth with azolla has the potential to increase N nutrients in water hyacinth compost