562 research outputs found
Sustainable Tourism Marketing Strategies at UNESCO World Heritage Sites
Designation as a United Nations Educational Scientific and Cultural Organization (UNESCO) World Heritage site has a significant impact on the tourism development and sustainability of a site, city, region or country. World Heritage sites bring a certain level of prestige and international recognition, but they also have an impact on the local communities as they impact day to day life and rituals of the residents. Several paradigms exist in evaluating the success of a UNESCO World Heritage site. This paper specifically examines how marketing strategies bolster sustainable tourism efforts
Seed systems and crop genetic diversity in agroecosystems
Poster presented at the First Diversitas Open Science Conference. Oaxaca (Mexico), 9-12 Nov 200
Early embryonic requirement for nucleoporin Nup35/NPP-19 in nuclear assembly
11 pages, 8 figures, 3 tables.-- PMID: 19146848 [PubMed].-- Available online Dec 30, 2008.Supporting information (Suppl. figs S1-S5, movies S1-S6) available at: http://dx.doi.org/10.1016/j.ydbio.2008.12.024Nuclear pore complexes (NPCs) are gateways for transport between the nucleus and cytoplasm of eukaryotic cells and play crucial roles in regulation of gene expression. NPCs are composed of multiple copies of not, vert, similar 30 different nucleoporins (nups) that display both ubiquitous and cell type specific functions during development. Vertebrate Nup35 (also known as Nup53) was previously described to interact with Nup93, Nup155 and Nup205 and to be required for nuclear envelope (NE) assembly in vitro. Here, we report the first in vivo characterization of a Nup35 mutation, npp-19(tm2886), and its temperature-dependent effects on Caenorhabditis elegans embryogenesis. At restrictive temperature, npp-19(tm2886) embryos exhibit chromosome missegregation, nuclear morphology defects and die around mid-gastrulation. Depletion of Nup35/NPP-19 inhibits NE localization of Nup155/NPP-8, NPC assembly and nuclear lamina formation. Consequently, nuclear envelope function, including nucleo-cytoplasmic transport, is impaired. In contrast, recruitment of Nup107/NPP-5, LEM-2 and nuclear membranes to the chromatin surface is Nup35/NPP-19-independent, suggesting an uncoupling of nuclear membrane targeting and NPC assembly in the absence of Nup35/NPP-19. We propose that Nup35/NPP-19 has an evolutionary conserved role in NE formation and function, and that this role is particularly critical during the rapid cell divisions of early embryogenesis.This work was funded by grants from the Spanish Ministry of Science and Education (RYC-2003-001521, BFU-2004-01096, BFU-2007-60116) to PA. In addition, we wish to acknowledge Fundación Ramón Areces for a fellowship to ER and Junta de Andalucía for institutional support.Peer reviewe
TESS Discovery of an ultra-short-period planet around the nearby M dwarf LHS 3844
Data from the newly-commissioned \textit{Transiting Exoplanet Survey
Satellite} (TESS) has revealed a "hot Earth" around LHS 3844, an M dwarf
located 15 pc away. The planet has a radius of and
orbits the star every 11 hours. Although the existence of an atmosphere around
such a strongly irradiated planet is questionable, the star is bright enough
(, ) for this possibility to be investigated with transit and
occultation spectroscopy. The star's brightness and the planet's short period
will also facilitate the measurement of the planet's mass through Doppler
spectroscopy.Comment: 10 pages, 4 figures. Submitted to ApJ Letters. This letter makes use
of the TESS Alert data, which is currently in a beta test phase, using data
from the pipelines at the TESS Science Office and at the TESS Science
Processing Operations Cente
Droplet Behavior within an LPP Ambiance
This paper deals with the numerical simulation of droplet dispersion and evaporation within an LPP (Lean Premix Prevaporized) burner. The Eulerian-Lagrangian approach was used for this purpose, and a fully two way-coupling was accounted for. For the phase transition, a non-equilibrium evaporation model was applied that differs strongly from the equilibrium one where there are high evaporation rates. The non-equilibrium conditions were fulfilled in the investigated configuration, as the droplets at the inlet had a mean diameter of 50mm. The numerical results of water droplet velocities, corresponding fluctuations, and diameters were compared with experimental data. Good agreement was found
Numerical investigation of droplet evaporation modeling in combustion environment
Two of the most employed droplet evaporation models in CFD (Computational Fluid Dynamics) applications are analyzed in a numerical context. Both are the infinite liquid conductivity versions of Abramzon-Sirignano and Miller et al. models. The study comprehends a systematic investigation of both models and different procedures used to address thermo-chemical properties. Initially, investigations are addressed in a single droplet framework for different fuels (i.e. ethanol, hexane, and decane). Herein, available experimental data give support to the corresponding discussions. In a second part, the two models and the simplification of the surrounding gas mixture by air are investigated in flames propagating in ethanol droplet mists. A detailed chemistry model is used to represent the combustion of ethanol in air. Results help the choice of methods employed for droplet evaporation modeling in a general context. The methodology adopted in our analyses allows the assessment of each simplification and converges to an optimal combination of methods.</p
Influence of Growth Stage and Leaf Age on Expression of the Components of Partial Resistance of Faba Bean to Botrytis fabae Sard.
In detached leaf tests on faba bean (Vicia faba L.), genotypes partially resistant and susceptible to Botrytis
fabae were examined. Expression of four components of partial resistance to a virulent isolate of B. fabae differed
depending on the plant age and the leaf age of the genotypes. The incubation period of resistant genotypes at the
podding stage was longer than that of susceptible genotypes at the same stage. The area under disease progress
curve (AUDPC) of the lesion size increased from the seedling to the flowering stage but declined at the podding stage
in all genotypes. Differences between resistant and susceptible genotypes for lesion size were significant except on
old leaves from plants at the podding stage. The latent period decreased, and spore production increased with increasing
growth and leaf age but there was significant interaction with the genotype. These last two components of
partial resistance were more clearly expressed at all growth stages on FRY167 (highly resistant) but were expressed
only at the seedling and podding stages on FRY7 (resistant). The resistant line BPL710 was not significantly different
from the susceptible genotypes for the latent period at any growth stage, and for spore production at the seedling
and flowering stages. Leaf age affected all genotypes, but with a significant interaction between leaf age and growth
stage. Components of partial resistance were more strongly expressed on young leaves from plants at the seedling or
flowering stage
Sensory Communication
Contains table of contents for Section 2, an introduction and reports on fourteen research projects.National Institutes of Health Grant RO1 DC00117National Institutes of Health Grant RO1 DC02032National Institutes of Health/National Institute on Deafness and Other Communication Disorders Grant R01 DC00126National Institutes of Health Grant R01 DC00270National Institutes of Health Contract N01 DC52107U.S. Navy - Office of Naval Research/Naval Air Warfare Center Contract N61339-95-K-0014U.S. Navy - Office of Naval Research/Naval Air Warfare Center Contract N61339-96-K-0003U.S. Navy - Office of Naval Research Grant N00014-96-1-0379U.S. Air Force - Office of Scientific Research Grant F49620-95-1-0176U.S. Air Force - Office of Scientific Research Grant F49620-96-1-0202U.S. Navy - Office of Naval Research Subcontract 40167U.S. Navy - Office of Naval Research/Naval Air Warfare Center Contract N61339-96-K-0002National Institutes of Health Grant R01-NS33778U.S. Navy - Office of Naval Research Grant N00014-92-J-184
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