Two-Higgs-Doublet type-II and -III models and t→cht\to c h at the LHC

We study the constraints of the generic two-Higgs-doublet model (2HDM) type-III and the impacts of the new Yukawa couplings. For comparisons, we revisit the analysis in the 2HDM type-II. To understand the influence of all involving free parameters and to realize their correlations, we employ $\chi$-square fitting approach by including theoretical and experimental constraints, such as S, T, and U oblique parameters, the production of standard model Higgs and its decay to $\gamma\gamma$, $WW^*/ZZ^*$, $\tau^+\tau^-$, etc. The errors of analysis are taken at $68\%$, $95.5\%$, and $99.7\%$ confidence levels. Due to the new Yukawa couplings being associated with $\cos(\beta-\alpha)$ and $\sin(\beta -\alpha)$, we find that the allowed regions for $\sin\alpha$ and $\tan\beta$ in the type-III model can be broader when the dictated parameter $\chi_F$ is positive; however, for negative $\chi_F$, the limits are stricter than those in the type-II model. By using the constrained parameters, we find that the deviation from the SM in the $h\to Z\gamma$ can be of ${\cal O}(10\%)$. Additionally, we also study the top-quark flavor-changing processes induced at the tree level in the type-III model and find that when all current experimental data are considered, we get $Br(t\to c(h, H) )< 10^{-3}$ for $m_h=125.36$ and $m_H=150$ GeV and $Br(t\to cA)$ slightly exceeds $10^{-3}$ for $m_A =130$ GeV.Comment: 22 pages, 11 figures. v3: Slight change in the abstract, Figure.1 added and commented, the conclusion remains unchange

Three dimensional structure prediction of fatty acid binding site on human transmembrane receptor CD36

CD36 is an integral membrane protein which is thought to have a hairpin-like structure with alpha-helices at the C and N terminals projecting through the membrane as well as a larger extracellular loop. This receptor interacts with a number of ligands including oxidized low density lipoprotein and long chain fatty acids (LCFAs). It is also implicated in lipid metabolism and heart diseases. It is therefore important to determine the 3D structure of the CD36 site involved in lipid binding. In this study, we predict the 3D structure of the fatty acid (FA) binding site [127–279 aa] of the CD36 receptor based on homology modeling with X-ray structure of Human Muscle Fatty Acid Binding Protein (PDB code: 1HMT). Qualitative and quantitative analysis of the resulting model suggests that this model was reliable and stable, taking in consideration over 97.8% of the residues in the most favored regions as well as the significant overall quality factor. Protein analysis, which relied on the secondary structure prediction of the target sequence and the comparison of 1HMT and CD36 [127–279 aa] secondary structures, led to the determination of the amino acid sequence consensus. These results also led to the identification of the functional sites on CD36 and revealed the presence of residues which may play a major role during ligand-protein interactions

Van der Waals induced polarization of molecules adsorbed on small metallic spheres : anisotropy and nonlocality effects

The calculation of Van der Waals induced polarization of molecules interacting with small metallic spheres is based on the spherical-tensor theory by using the response field susceptibility of the sphere. The first Euler angle appearing in the expression giving this polarization exhibits the anisotropy of the molecule. In order to illustrate the non locality and anisotropy effects as well as the importance of the metallic sphere curvature on the induced polarization magnitudes, we present numerical results for typical systems (HF, HCl) on (Ag, Al and Cu).The calculation of Van der Waals induced polarization of molecules interacting with small metallic spheres is based on the spherical-tensor theory by using the response field susceptibility of the sphere. The first Euler angle appearing in the expression giving this polarization exhibits the anisotropy of the molecule. In order to illustrate the non locality and anisotropy effects as well as the importance of the metallic sphere curvature on the induced polarization magnitudes, we present numerical results for typical systems (HF, HCl) on (Ag, Al and Cu)

Reponses Of A Metallic Bubble: A Self-Consistent Calculation Including Correlation And Exchange Effects

The Van der Waals energy of molecules interacting with metallic bubbles is determined from spherical-tensor theory by using the response field susceptibility of the spherical bubble. The correlation and exchange effects of the electron response inside the metal are included by using the local density approximation (LDA). The dependence of the Van der Waals energy on the first Euler angle is manifestation of the anisotropy of the interaction. In order to illustrate the non-locality and the correlation and exchange effects as well as the importance of the spherical bubble curvature and anisotropy of the interaction on the potential magnitudes, we present numerical results for typical systems (HF,HCl) molecules on (Ag,Al) surfaces.The Van der Waals energy of molecules interacting with metallic bubbles is determined from spherical-tensor theory by using the response field susceptibility of the spherical bubble. The correlation and exchange effects of the electron response inside the metal are included by using the local density approximation (LDA). The dependence of the Van der Waals energy on the first Euler angle is manifestation of the anisotropy of the interaction. In order to illustrate the non-locality and the correlation and exchange effects as well as the importance of the spherical bubble curvature and anisotropy of the interaction on the potential magnitudes, we present numerical results for typical systems (HF,HCl) molecules on (Ag,Al) surfaces

Fractionation of lead in soil by isotopic dilution and sequential extraction

‘Reactivity’ or ‘lability’ of lead is difficult to measure using traditional methods. We investigated the use of isotopic dilution with 204Pb to determine metal reactivity in four soils historically contaminated with contrasting sources of Pb, including (i) petrol-derived Pb, (ii) Pb/Zn minespoil, (iii) long-term sewage sludge application and (iv) 19th century urban waste disposal; total soil Pb concentrations ranged from 217 to 13 600 mg kg–1. A post-spike equilibration period of 3 days and suspension in 5.0 × 10–4 M ethylenediaminetetraacetic acid provided reasonably robust conditions for measuring isotopically exchangeable Pb. However, in acidic organic soils a dilute Ca(NO3)2 electrolyte may be preferable to avoid mobilisation of ‘non-labile’ Pb. Results showed that the reactive pool of soil Pb can be a large proportion of the total soil lead content but varies with the original Pb source. A comparison of isotopic exchangeability with the results of a sequential extraction procedure showed that (isotopically) ‘non-labile’ Pb may be broadly equated with ‘residual’ Pb in organic soils. However, in mineral soils the ‘carbonate’ and ‘oxide-bound’ Pb fractions included non-labile forms of Pb. The individual isotopic signatures of labile and non-labile Pb pools suggested that, despite prolonged contact with soil, differences between the lability of the original contaminant and the native soil Pb may remain

Risk factors caused by scorpion stings and envenomations in the province of Kelâa Des Sraghna (Morocco)

The present study aims to elucidate the risk factors involved in deaths caused by scorpion envenomation. A retrospective study was carried out in the province of Kelâa des Sraghna from 2003 to 2004. The hospital charts of scorpion envenomation cases treated in the Essalama Hospital in Kelâa des Sraghna were exhaustively analyzed. Our study contains 31 cases of death among 470 hospitalization cases. Most stings had occurred during the hot period peaking in July and August (54.6%). Moreover, the scorpion stings occurred at night in 60.1% of the cases, between 6:00 pm and 6:00 am. In addition, all age groups were affected by envenomation, with a higher frequency in children aged less than 15 years (68.3%). The envenomation rate (class II + class III) was 70.9%. The statistical analysis of the data shows that being less than 15 years old, having been stung during the night and belonging to class III are risk factors that aggravate vital prognosis of hospitalized patients. Furthermore, clinical severity factors, elicited by relative risk analysis, are cardiovascular, respiratory and neurological vital distresses, with relative risks of 14.84, 11.92 and 48.33, respectively. The results of our study clearly displayed the severity and extent of the scorpion envenomation problem. Thus, great attention must be paid to this region of Morocco by the national health authorities

Analysis of the gg→H→hh→4τgg\to H\to hh\to4\tau process in the 2HDM lepton specific model at the LHC

We analyse the signature of a light Higgs boson pair in the 2-Higgs Doublet Model(2HDM) Type-X (or lepton specific) over the parameter spaces allowed by theoretical self-consistency requirements as well as the latest experimental constraints from the Large Hadron Collider (LHC), precision test data and $B$ physics. Over the viable regions of the latter, wherein the Standard Model (SM)-like Higgs boson discovered at the LHC in 2012 is the heavier CP-even state of the 2HDM, $H$, it is found that the SM-like Higgs boson can decay into a pair of the lighter CP-even Higgs boson, $h$, via the process $H\to hh$ with a Branching Ratio (BR) of $5\%-10\%$ or so, (with $2 m_h < m_H =125$ GeV). Furthermore, in the Type-X scenario, the lighter Higgs bosons $h$ can dominantly decay into two $\tau$'s due to a large $\tan\beta$. Therefore, the pair of lighter Higgs bosons can altogether decay into a 4 $\tau$ final state. In order to suppress the huge SM background events, we confine ourself to consider the fraction of signal events with two Same-Sign (SS) $\tau$'s further decaying into same sign leptons while the other two $\tau$'s decay hadronically. By using Monte Carlo (MC) and Machine Learning (ML) tools, we thus focus on the analysis of the signal process $pp\to H\to hh\to \tau^{+}\tau^{-}\tau^{+}\tau^{-}\to \ell v_\ell \ell v_\ell \tau_h \tau_h$ (where $\ell= e, \mu$ and $\tau_h$ means a hadronic decay of the $\tau$) and explore the feasibility of such a search at the LHC for a collision energy $\sqrt{s}=~\text{14 TeV}$ and a luminosity $\text{300}~\text{fb}^{-1}$Comment: 19 pages, 7 figures, 7 tables. arXiv admin note: text overlap with arXiv:2305.0578

Talking about chronic pain in family settings: a glimpse of older persons' everyday realities.

The expression of chronic pain remains a delicate matter for those older persons who suffer from this condition. If many studies highlight the difficulties of putting pain into words, scarce are those that take into account how given social networks can facilitate or prevent its expression. Based on a qualitative study that explores the communication about chronic pain in older persons' social network, this article reports on this key issue of talking about health in later life within family settings and provides clinicians with information about the way older persons with chronic conditions perceive their everyday realities and social relations. A multidisciplinary research team (medicine, linguistics and psychology) interviewed 49 persons with chronic pain, all from the French-speaking part of Switzerland, aged 75 and older, without any major cognitive or auditory impairments. After transcription, the interviews were analyzed by combining content and discourse analysis with social network theories. Communication about chronic pain depends significantly on the position of the interlocutors within the family structure, with a preference for direct relatives or individuals with similar difficulties. In social networks, the ability to communicate about chronic pain is both a resource (by allowing older persons to get help or by strengthening interpersonal relations) and a challenge (by threatening their autonomy, social relations or self-esteem). The study shows the predominance of the nuclear family (partner, children) in communication relating specifically to the everyday management of chronic pain. This state of affairs is, nevertheless, balanced by issues of (loss of) autonomy. These findings, in line with current trends in geriatrics, could benefit future reflections on the scope and limits of including relatives in the care of older patients with chronic conditions