The clinical relevance of oliguria in the critically ill patient : Analysis of a large observational database

Funding Information: Marc Leone reports receiving consulting fees from Amomed and Aguettant; lecture fees from MSD, Pfizer, Octapharma, 3 M, Aspen, Orion; travel support from LFB; and grant support from PHRC IR and his institution. JLV is the Editor-in-Chief of Critical Care. The other authors declare that they have no relevant financial interests. Publisher Copyright: © 2020 The Author(s). Copyright: Copyright 2020 Elsevier B.V., All rights reserved.Background: Urine output is widely used as one of the criteria for the diagnosis and staging of acute renal failure, but few studies have specifically assessed the role of oliguria as a marker of acute renal failure or outcomes in general intensive care unit (ICU) patients. Using a large multinational database, we therefore evaluated the occurrence of oliguria (defined as a urine output 16 years) patients in the ICON audit who had a urine output measurement on the day of admission were included. To investigate the association between oliguria and mortality, we used a multilevel analysis. Results: Of the 8292 patients included, 2050 (24.7%) were oliguric during the first 24 h of admission. Patients with oliguria on admission who had at least one additional 24-h urine output recorded during their ICU stay (n = 1349) were divided into three groups: transient - oliguria resolved within 48 h after the admission day (n = 390 [28.9%]), prolonged - oliguria resolved > 48 h after the admission day (n = 141 [10.5%]), and permanent - oliguria persisting for the whole ICU stay or again present at the end of the ICU stay (n = 818 [60.6%]). ICU and hospital mortality rates were higher in patients with oliguria than in those without, except for patients with transient oliguria who had significantly lower mortality rates than non-oliguric patients. In multilevel analysis, the need for RRT was associated with a significantly higher risk of death (OR = 1.51 [95% CI 1.19-1.91], p = 0.001), but the presence of oliguria on admission was not (OR = 1.14 [95% CI 0.97-1.34], p = 0.103). Conclusions: Oliguria is common in ICU patients and may have a relatively benign nature if only transient. The duration of oliguria and need for RRT are associated with worse outcome.publishersversionPeer reviewe

He-Hg+ and He-Cd+ Lasers

Laser oscillation in ionized metal vapors in wide spectral range (from UV to IR) is known to date. Different type of gas discharges are used for metal ion laser excitation - continuous wave and pulsed positive column discharge; continuous wave and pulsed hollow cathode discharge; high frequency discharge and electron beam excitation. Each of these discharges has its advantages and drawbacks. An investigation is needed in metal vapor ion laser development involving new methods for excitation of this laser class.</jats:p

A simple method for theoretical determination of the radius- and time-dependent electron temperatures in nanosecond pulsed longitudinal discharges in helium and neon assuming a bi-Maxwellian electron energy distribution function

Abstract Assuming a bi-Maxwellian electron energy distribution function, the temporal and radial distribution of the electron temperature is determined in nanosecond pulsed longitudinal discharges used for excitation of two prospective high-power gas-discharge lasers, namely, a deep ultraviolet Cu+ Ne-H2-CuBr laser and a He-Sr+ recombination laser. For this purpose, the parameters of the set of nonstationary heat-conduction equations for the two groups of electrons, namely, the electrical power density and the specific heat capacity, are determined for each group. A 2D(r,t) numerical model is also developed in order to solve the set of the equations.</jats:p