39,421 research outputs found
Hadronic Correlators from All-point Quark Propagators
A method for computing all-point quark propagators is applied to a variety of
processes of physical interest in lattice QCD. The method allows, for example,
efficient calculation of disconnected parts and full momentum-space 2 and 3
point functions. Examples discussed include: extraction of chiral Lagrangian
parameters from current correlators, the pion form factor, and the unquenched
eta-prime.Comment: LATTICE01(Algorithms and Machines
Cool-associated Tyrosine-phosphorylated Protein 1 Is Required for the Anchorage-independent Growth of Cervical Carcinoma Cells by Binding Paxillin and Promoting AKT Activation.
Cool-associated tyrosine-phosphorylated protein 1 (Cat-1) is a signaling scaffold as well as an ADP-ribosylation factor-GTPase-activating protein. Although best known for its role in cell migration, we recently showed that the ability of Cat-1 to bind paxillin, a major constituent of focal complexes, is also essential for the anchorage-independent growth of HeLa cervical carcinoma cells. Here we set out to learn more about the underlying mechanism by which Cat-paxillin interactions mediate this effect. We show that knocking down paxillin expression in HeLa cells promotes their ability to form colonies in soft agar, whereas ectopically expressing paxillin in these cells inhibits this transformed growth phenotype. Although knocking down Cat-1 prevents HeLa cells from forming colonies in soft agar, when paxillin is knocked down together with Cat-1, the cells are again able to undergo anchorage-independent growth. These results suggest that the requirement of Cat-1 for this hallmark of cellular transformation is coupled to its ability to bind paxillin and abrogate its actions as a negative regulator of anchorage-independent growth. We further show that knocking down Cat-1 expression in HeLa cells leads to a reduction in Akt activation, which can be reversed by knocking down paxillin. Moreover, expression of constitutively active forms of Akt1 and Akt2 restores the anchorage-independent growth capability of HeLa cells depleted of Cat-1 expression. Together, these findings highlight a novel mechanism whereby interactions between Cat-1 and its binding partner paxillin are necessary to ensure sufficient Akt activation so that cancer cells are able to grow under anchorage-independent conditions
Engineering Heteromaterials to Control Lithium Ion Transport Pathways.
Safe and efficient operation of lithium ion batteries requires precisely directed flow of lithium ions and electrons to control the first directional volume changes in anode and cathode materials. Understanding and controlling the lithium ion transport in battery electrodes becomes crucial to the design of high performance and durable batteries. Recent work revealed that the chemical potential barriers encountered at the surfaces of heteromaterials play an important role in directing lithium ion transport at nanoscale. Here, we utilize in situ transmission electron microscopy to demonstrate that we can switch lithiation pathways from radial to axial to grain-by-grain lithiation through the systematic creation of heteromaterial combinations in the Si-Ge nanowire system. Our systematic studies show that engineered materials at nanoscale can overcome the intrinsic orientation-dependent lithiation, and open new pathways to aid in the development of compact, safe, and efficient batteries
Oxygen surface exchange kinetics of erbia-stabilized bismuth oxide
The surface oxygen exchange kinetics of bismuth\ud
oxide stabilized with 25 mol% erbia (BE25) has been studied\ud
in the temperature and pO2 ranges 773–1,023 K and 0.1–\ud
0.95 atm, respectively, using pulse-response 18O–16O isotope\ud
exchange measurements. The results indicate that BE25\ud
exhibits a comparatively high exchange rate, which is rate\ud
determined by the dissociative adsorption of oxygen. Defect\ud
chemical considerations and the observed pO2\ud
1=2 dependence\ud
of the rate of dissociative oxygen adsorption suggest\ud
electron transfer to intermediate superoxide ions as the rate\ud
determining step in surface oxygen exchange on BE2
The Second Virial Coefficient of Spin-1/2 Interacting Anyon System
Evaluating the propagator by the usual time-sliced manner, we use it to
compute the second virial coefficient of an anyon gas interacting through the
repulsive potential of the form . All the cusps for the
unpolarized spin-1/2 as well as spinless cases disappear in the
limit, where is a frequency of harmonic oscillator which is introduced
as a regularization method. As approaches to zero, the result reduces to
the noninteracting hard-core limit.Comment: 9 pages, 2 figs include
Filtered density functions from direct numerical simulation of a reactive jet in cross-flow
Direct numerical simulation (DNS) with multi-step hydrogen-air chemical kinetics is used to investigate the nearfield of a flame stabilized above a reactive jet in cross-flow (JICF). JICF configurations are typically used where rapid mixing is desirable; classical applications are fuel injection nozzles and dilution holes in gas turbine combustors. Due to the computational cost of DNS, approximate solution methods such as large-eddy simulation (LES) are essential to parametrically study the effect of changing fuel jet configurations on the far field, but these methods require submodels capable of accurately capturing the near-field flame stabilization for success. By incorporating a wealth of turbulence chemistry interactions (between the flame and vorticity generated by the jet shear layer instability as well as product recirculation by a large counter-rotating vortex pair), this DNS is exceptionally well suited to exploration of unclosed terms in LES formulations such as the chemical source-term. One quantity of direct relevance to several models for stratified combustion, such as the Bray-Moss (BM) model and doubly-conditional source-term estimation (DCSE), is the filtered density function for the mixture fraction ! and partially premixed progress variable c. Empirical extraction of the filtered density functions of progress variable and mixture fraction at two representative locations demonstrates the complexity of approximating these two functions from a one- or two-parameter functional form
Topology Changing Process of Coalescing Black Holes on Eguchi-Hanson Space
We numerically study the event horizons of two kinds of five-dimensional
coalescing black hole solutions with different asymptotic structures: the
five-dimensional Kastor-Traschen solution (5DKT) and the coalescing black hole
solution on Eguchi-Hanson space (CBEH). Topologies of the spatial infinity are
and , respectively. We show that
the crease sets of event horizons are topologically in 5DKT and
in CBEH, respectively. If we choose the time slices
which respect space-time symmetry, the first contact points of the coalescing
process is a point in the 5DKT case but a in the CBEH case. We also
find that in CBEH, time slices can be chosen so that a black ring with topology can be also formed during a certain intermediate
period unlike the 5DKT.Comment: 13 pages, 17 figure
Recent results using all-point quark propagators
Pseudofermion methods for extracting all-point quark propagators are
reviewed, with special emphasis on techniques for reducing or eliminating
autocorrelations induced by low eigenmodes of the quark Dirac operator. Recent
applications, including high statistics evaluations of hadronic current
correlators and the pion form factor, are also described.Comment: LateX, 3 pages, 6 eps figures, Lattice2002(algor), corrected some
typo
Chaos at the border of criticality
The present paper points out to a novel scenario for formation of chaotic
attractors in a class of models of excitable cell membranes near an
Andronov-Hopf bifurcation (AHB). The mechanism underlying chaotic dynamics
admits a simple and visual description in terms of the families of
one-dimensional first-return maps, which are constructed using the combination
of asymptotic and numerical techniques. The bifurcation structure of the
continuous system (specifically, the proximity to a degenerate AHB) endows the
Poincare map with distinct qualitative features such as unimodality and the
presence of the boundary layer, where the map is strongly expanding. This
structure of the map in turn explains the bifurcation scenarios in the
continuous system including chaotic mixed-mode oscillations near the border
between the regions of sub- and supercritical AHB. The proposed mechanism
yields the statistical properties of the mixed-mode oscillations in this
regime. The statistics predicted by the analysis of the Poincare map and those
observed in the numerical experiments of the continuous system show a very good
agreement.Comment: Chaos: An Interdisciplinary Journal of Nonlinear Science
(tentatively, Sept 2008
Silicon Solar Cell Process Development, Fabrication and Analysis, Phase 1
Solar cells from RTR ribbons, EFG (RF and RH) ribbons, dendritic webs, Silso wafers, cast silicon by HEM, silicon on ceramic, and continuous Czochralski ingots were fabricated using a standard process typical of those used currently in the silicon solar cell industry. Back surface field (BSF) processing and other process modifications were included to give preliminary indications of possible improved performance. The parameters measured included open circuit voltage, short circuit current, curve fill factor, and conversion efficiency (all taken under AM0 illumination). Also measured for typical cells were spectral response, dark I-V characteristics, minority carrier diffusion length, and photoresponse by fine light spot scanning. the results were compared to the properties of cells made from conventional single crystalline Czochralski silicon with an emphasis on statistical evaluation. Limited efforts were made to identify growth defects which will influence solar cell performance
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