401 research outputs found
Search for WW and WZ production in lepton plus jets final state at CDF
We present a search for WW and WZ production in final states that contain a charged lepton (electron or muon) and at least two jets, produced in sqrt(s) = 1.96 TeV ppbar collisions at the Fermilab Tevatron, using data corresponding to 1.2 fb-1 of integrated luminosity collected with the CDF II detector. Diboson production in this decay channel has yet to be observed at hadron colliders due to the large single W plus jets background. An artificial neural network has been developed to increase signal sensitivity, as compared with an event selection based on conventional cuts. We set a 95% confidence level upper limit of sigma_{WW}* BR(W->lnu,W->jets)+ sigma_{WZ}*BR(W->lnu,Z->jets)We present a search for WW and WZ production in final states that contain a charged lepton (electron or muon) and at least two jets, produced in √s=1.96 TeV pp̅ collisions at the Fermilab Tevatron, using data corresponding to 1.2 fb-1 of integrated luminosity collected with the CDF II detector. Diboson production in this decay channel has yet to be observed at hadron colliders due to the large single W plus jets background. An artificial neural network has been developed to increase signal sensitivity, as compared with an event selection based on conventional cuts. We set a 95% confidence level upper limit of σWW×BR(W→ℓνℓ,W→jets)+σWZ×BR(W→ℓνℓ,Z→jets)<2.88 pb, which is consistent with the standard model next-to-leading-order cross section calculation for this decay channel of 2.09±0.12 pb.Peer reviewe
First measurement of the Hubble Constant from a Dark Standard Siren using the Dark Energy Survey Galaxies and the LIGO/Virgo Binary–Black-hole Merger GW170814
International audienceWe present a multi-messenger measurement of the Hubble constant H 0 using the binary–black-hole merger GW170814 as a standard siren, combined with a photometric redshift catalog from the Dark Energy Survey (DES). The luminosity distance is obtained from the gravitational wave signal detected by the Laser Interferometer Gravitational-Wave Observatory (LIGO)/Virgo Collaboration (LVC) on 2017 August 14, and the redshift information is provided by the DES Year 3 data. Black hole mergers such as GW170814 are expected to lack bright electromagnetic emission to uniquely identify their host galaxies and build an object-by-object Hubble diagram. However, they are suitable for a statistical measurement, provided that a galaxy catalog of adequate depth and redshift completion is available. Here we present the first Hubble parameter measurement using a black hole merger. Our analysis results in , which is consistent with both SN Ia and cosmic microwave background measurements of the Hubble constant. The quoted 68% credible region comprises 60% of the uniform prior range [20, 140] km s−1 Mpc−1, and it depends on the assumed prior range. If we take a broader prior of [10, 220] km s−1 Mpc−1, we find (57% of the prior range). Although a weak constraint on the Hubble constant from a single event is expected using the dark siren method, a multifold increase in the LVC event rate is anticipated in the coming years and combinations of many sirens will lead to improved constraints on H 0
GW170104: Observation of a 50-Solar-Mass Binary Black Hole Coalescence at Redshift 0.2
We describe the observation of GW170104, a gravitational-wave signal produced by the coalescence of a pair of stellar-mass black holes. The signal was measured on January 4, 2017 at 10: 11: 58.6 UTC by the twin advanced detectors of the Laser Interferometer Gravitational-Wave Observatory during their second observing run, with a network signal-to-noise ratio of 13 and a false alarm rate less than 1 in 70 000 years. The inferred component black hole masses are 31.2(-6.0)(+8.4)M-circle dot and 19.4(-5.9)(+5.3)M(circle dot) (at the 90% credible level). The black hole spins are best constrained through measurement of the effective inspiral spin parameter, a mass-weighted combination of the spin components perpendicular to the orbital plane, chi(eff) =
-0.12(-0.30)(+0.21) . This result implies that spin configurations with both component spins positively aligned with the orbital angular momentum are disfavored. The source luminosity distance is 880(-390)(+450) Mpc corresponding to a redshift of z = 0.18(-0.07)(+0.08) . We constrain the magnitude of modifications to the gravitational-wave dispersion relation and perform null tests of general relativity. Assuming that gravitons are dispersed in vacuum like massive particles, we bound the graviton mass to m(g) <= 7.7 x 10(-23) eV/c(2). In all cases, we find that GW170104 is consistent with general relativity
Endothelial dysfunction and diabetes: roles of hyperglycemia, impaired insulin signaling and obesity
The economic impact of moderate stage Alzheimer's disease in Italy: Evidence from the UP-TECH randomized trial
Background: There is consensus that dementia is the most burdensome disease for modern societies. Few cost-of-illness studies examined the complexity of Alzheimer's disease (AD) burden, considering at the same time health and social care, cash allowances, informal care, and out-of-pocket expenditure by families. Methods: This is a comprehensive cost-of-illness study based on the baseline data from a randomized controlled trial (UP-TECH) enrolling 438 patients with moderate AD and their primary caregiver living in the community. Results: The societal burden of AD, composed of public, patient, and informal care costs, was about �20,000/yr. Out of this, the cost borne by the public sector was �4,534/yr. The main driver of public cost was the national cash-for-care allowance (�2,324/yr), followed by drug prescriptions (�1,402/yr). Out-of-pocket expenditure predominantly concerned the cost of private care workers. The value of informal care peaked at �13,590/yr. Socioeconomic factors do not influence AD public cost, but do affect the level of out-of-pocket expenditure. Conclusion: The burden of AD reflects the structure of Italian welfare. The families predominantly manage AD patients. The public expenditure is mostly for drugs and cash-for-care benefits. From a State perspective in the short term, the advantage of these care arrangements is clear, compared to the cost of residential care. However, if caregivers are not adequately supported, savings may be soon offset by higher risk of caregiver morbidity and mortality produced by high burden and stress. The study has been registered on the website www.clinicaltrials.org (Trial Registration number: NCT01700556). Copyright � International Psychogeriatric Association 2015
Searching the inclusive l γe T+b-quark signature for radiative top quark decay and non-standard-model processes
We compare the inclusive production of events containing a lepton (á), a photon (γ), significant transverse momentum imbalance (E T), and a jet identified as containing a b-quark, to SM predictions. The search uses data produced in proton-antiproton collisions at s=1.96TeV corresponding to 1.9fb-1 of integrated luminosity taken with the CDF detector. We find 28 áγbET events versus an expectation of 31.0-3.5+4.1 events. If we further require events to contain at least three jets and large total transverse energy, the largest SM source is radiative top-quark pair production, tt̄+γ. In the data we observe 16 tt̄γ candidate events versus an expectation from SM sources of 11.2-2.1+2.3. Assuming the difference between the observed number and the predicted non-top-quark total of 6.8-2.0+2.2 is due to SM top-quark production, we estimate the tt̄γ cross section to be 0.15±0.08pb. © 2009 The American Physical Society
Measurement of resonance parameters of orbitally excited narrow B0 mesons
We report a measurement of resonance parameters of the orbitally excited (L=1) narrow B0 mesons in decays to B(*)+Ï€- using 1.7fb-1 of data collected by the CDF II detector at the Fermilab Tevatron. The mass and width of the B2*0 state are measured to be m(B2*0)=5740.2-1.8+1. 7(stat)-0.8+0.9(syst)MeV/c2 and Î (B2*0)=22.7-3.2+3.8(stat)-10. 2+3.2(syst)MeV/c2. The mass difference between the B2*0 and B10 states is measured to be 14.9-2.5+2.2(stat)-1.4+1.2(syst)MeV/c2, resulting in a B10 mass of 5725.3-2.2+1.6(stat)-1.5+1.4(syst)MeV/c2. This is currently the most precise measurement of the masses of these states and the first measurement of the B2*0 width. © 2009 The American Physical Society
Search for lepton flavor violating decays of a heavy neutral particle in p(p)over-bar collisions at root s=1.8 TeV
We report on a search for a high mass, narrow width particle that decays directly to emu, etau, or mutau. We use approximately 110 pb(-1) of data collected with the Collider Detector at Fermilab from 1992 to 1995. No evidence of lepton flavor violating decays is found. Limits are set on the production and decay of sneutrinos with R-parity violating interactions
Better prognosis in females with severe COVID-19 pneumonia: possible role of inflammation as potential mediator.
Objectives: Sex differences in COVID-19 severity and mortality have been described. Key aims of this analysis were to compare the risk of invasive mechanical ventilation (IMV) and mortality by sex and to explore whether variation in specific biomarkers could mediate this difference.
Methods: This was a retrospective, observational cohort study among patients with severe COVID- 19 pneumonia. A survival analysis was conducted to compare time to the composite endpoint of IMV or death by sex. Interaction was formally tested to compare the risk difference by sex in subsets. Mediation analysis with a binary endpoint IMV or death (yes/no) by end of follow-up for a number of inflammation/coagulation biomarkers in the context of counterfactual prediction was also conducted.
Results: Among 415 patients, 134 were females (32%) and 281 males (67%), median age 66 years (IQR 54-77). At admission, females showed a significantly less severe clinical and respiratory profiles with a higher PaO2/FiO2 (254 mmHg vs 191 mmHg; p=0.023). By 28 days from admission, 49.2% (95% CI: 39.6-58.9%) of males vs. 31.7% (17.9-45.4%) of females underwent IMV or death (log-rank pvalue<0.0001) and this amounted to a difference in HR of 0.40 (0.26-0.63, p=0.0001). The AUC in Creactive protein (CRP) over the study period appeared to explain 85% of this difference in risk by sex.
Conclusions: Our analysis confirms a difference in the risk of COVID-19 clinical progression by sex and provides a hypothesis for potential mechanisms leading to this. CRP showed a predominant role to mediate the difference in risk by sex
Measurement of the top quark mass at CDF using the `neutrino phi weighting' template method on a lepton plus isolated track sample
We present a measurement of the top quark mass with t{bar t} dilepton events produced in p{bar p} collisions at the Fermilab Tevatron ({radical}s = 1.96 TeV) and collected by the CDF II detector. A sample of 328 events with a charged electron or muon and an isolated track, corresponding to an integrated luminosity of 2.9 fb{sup -1}, are selected as t{bar t} candidates. To account for the unconstrained event kinematics, we scan over the phase space of the azimuthal angles ({phi}{sub {nu}1}, {phi}{sub {nu}2}) of neutrinos and reconstruct the top quark mass for each {phi}{sub {nu}1}, {phi}{sub {nu}2} pair by minimizing a {chi}{sup 2} function in the t{bar t} dilepton hypothesis. We assign {chi}{sup 2}-dependent weights to the solutions in order to build a preferred mass for each event. Preferred mass distributions (templates) are built from simulated t{bar t} and background events, and parameterized in order to provide continuous probability density functions. A likelihood fit to the mass distribution in data as a weighted sum of signal and background probability density functions gives a top quark mass of 165.5{sub -3.3}{sup +3.4}(stat.){+-}3.1(syst.) GeV/c{sup 2}
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