15,542 research outputs found
Low-Energy Properties of a One-dimensional System of Interacting bosons with Boundaries
The ground state properties and low-lying excitations of a (quasi)
one-dimensional system of longitudinally confined interacting bosons are
studied. This is achieved by extending Haldane's harmonic-fluid description to
open boundary conditions. The boson density, one-particle density matrix, and
momentum distribution are obtained accounting for finite-size and boundary
effects. Friedel oscillations are found in the density. Finite-size scaling of
the momentum distribution at zero momentum is proposed as a method to obtain
from the experiment the exponent that governs phase correlations. The strong
correlations between bosons induced by reduced dimensionality and interactions
are displayed by a Bijl-Jastrow wave function for the ground state, which is
also derived.Comment: Final published version. Minor changes with respect to the previous
versio
Hypocretin-1 receptors regulate the reinforcing and reward-enhancing effects of cocaine: pharmacological and behavioral genetics evidence.
Considerable evidence suggests that transmission at hypocretin-1 (orexin-1) receptors (Hcrt-R1) plays an important role in the reinstatement of extinguished cocaine-seeking behaviors in rodents. However, far less is known about the role for hypocretin transmission in regulating ongoing cocaine-taking behavior. Here, we investigated the effects of the selective Hcrt-R1 antagonist SB-334867 on cocaine intake, as measured by intravenous (IV) cocaine self-administration in rats. The stimulatory effects of cocaine on brain reward systems contribute to the establishment and maintenance of cocaine-taking behaviors. Therefore, we also assessed the effects of SB-334867 on the reward-enhancing properties of cocaine, as measured by cocaine-induced lowering of intracranial self-stimulation (ICSS) thresholds. Finally, to definitively establish a role for Hcrt-R1 in regulating cocaine intake, we assessed IV cocaine self-administration in Hcrt-R1 knockout mice. We found that SB-334867 (1-4 mg/kg) dose-dependently decreased cocaine (0.5 mg/kg/infusion) self-administration in rats but did not alter responding for food rewards under the same schedule of reinforcement. This suggests that SB-334867 decreased cocaine reinforcement without negatively impacting operant performance. SB-334867 (1-4 mg/kg) also dose-dependently attenuated the stimulatory effects of cocaine (10 mg/kg) on brain reward systems, as measured by reversal of cocaine-induced lowering of ICSS thresholds in rats. Finally, we found that Hcrt-R1 knockout mice self-administered far less cocaine than wildtype mice across the entire dose-response function. These data demonstrate that Hcrt-R1 play an important role in regulating the reinforcing and reward-enhancing properties of cocaine and suggest that hypocretin transmission is likely essential for establishing and maintaining the cocaine habit in human addicts
New Era, New Opportunity, Is GES DISC Ready for Big Data Challenge?
The new era of Big Data has opened doors for many new opportunities, as well as new challenges, for both Earth science research/application and data communities. As one of the twelve NASA data centers - Goddard Earth Sciences Data and Information Services Center (GES DISC), one of our great challenges has been how to help research/application community efficiently (quickly and properly) accessing, visualizing and analyzing the massive and diverse data in natural hazard research, management, or even prediction. GES DISC has archived over 2000 TB data on premises and distributed over 23,000 TB of data since 2010. Our data has been widely used in every phase of natural hazard management and research, i.e. long term risk assessment and reduction, forecasting and predicting, monitoring and detection, early warning, damage assessment and response. The big data challenge is not just about data storage, but also about data discoverability and accessibility, and even more, about data migration/mirroring in the cloud. This paper is going to demonstrate GES DISCs efforts and approaches of evolving our overall Web services and powerful Giovanni (Geospatial Interactive Online Visualization ANd aNalysis Infrastructure) tool into further improving data discoverability and accessibility. Prototype works will also be presented
Ytterbium divalency and lattice disorder in near-zero thermal expansion YbGaGe
While near-zero thermal expansion (NZTE) in YbGaGe is sensitive to
stoichiometry and defect concentration, the NZTE mechanism remains elusive. We
present x-ray absorption spectra that show unequivocally that Yb is nearly
divalent in YbGaGe and the valence does not change with temperature or with
nominally 1% B or 5% C impurities, ruling out a valence-fluctuation mechanism.
Moreover, substantial changes occur in the local structure around Yb with B and
C inclusion. Together with inelastic neutron scattering measurements, these
data indicate a strong tendency for the lattice to disorder, providing a
possible explanation for NZTE in YbGaGe.Comment: 4 pages, 4 figure, supplementary inf
Non-minimal Einstein-Yang-Mills-Higgs theory: Associated, color and color-acoustic metrics for the Wu-Yang monopole model
We discuss a non-minimal Einstein-Yang-Mills-Higgs model with uniaxial
anisotropy in the group space associated with the Higgs field. We apply this
theory to the problem of propagation of color and color-acoustic waves in the
gravitational background related to the non-minimal regular Wu-Yang monopole.Comment: 14 pages, no figure
Disorder in a Quantum Critical Superconductor
In four classes of materials, the layered copper-oxides, organics,
iron-pnictides and heavy-fermion compounds, an unconventional superconducting
state emerges as a magnetic transition is tuned toward absolute zero
temperature, that is, toward a magnetic quantum-critical point (QCP). In most
materials, the QCP is accessed by chemical substitutions or applied pressure.
CeCoIn5 is one of the few materials that are born as a quantum-critical
superconductor and, therefore, offers the opportunity to explore the
consequences of chemical disorder. Cadmium-doped crystals of CeCoIn5 are a
particularly interesting case where Cd substitution induces long-range magnetic
order, as in Zn-doped copper-oxides. Applied pressure globally supresses the
Cd-induced magnetic order and restores bulk superconductivity. Here we show,
however, that local magnetic correlations, whose spatial extent decreases with
applied pressure, persist at the extrapolated QCP. The residual droplets of
impurity-induced magnetic moments prevent the reappearance of conventional
signatures of quantum criticality, but induce a heterogeneous electronic state.
These discoveries show that spin droplets can be a source of electronic
heterogeneity in classes of strongly correlated electron systems and emphasize
the need for caution when interpreting the effects of tuning a correlated
system by chemical substitution.Comment: main text and supplementary informatio
Tame Functions with strongly isolated singularities at infinity: a tame version of a Parusinski's Theorem
Let f be a definable function, enough differentiable. Under the condition of
having strongly isolated singularities at infinity at a regular value c we give
a sufficient condition expressed in terms of the total absolute curvature
function to ensure the local triviality of the function f over a neighbourhood
of c and doing so providing the tame version of Parusinski's Theorem on complex
polynomials with isolated singularities at infinity.Comment: 20 page
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