Helical Packings and Phase Transformations of Soft Spheres in Cylinders

The phase behavior of helical packings of thermoresponsive microspheres inside glass capillaries is studied as a function of volume fraction. Stable packings with long-range orientational order appear to evolve abruptly to disordered states as particle volume fraction is reduced, consistent with recent hard sphere simulations. We quantify this transition using correlations and susceptibilities of the orientational order parameter psi_6. The emergence of coexisting metastable packings, as well as coexisting ordered and disordered states, is also observed. These findings support the notion of phase transition-like behavior in quasi-1D systems.Comment: 5 pages, with additional 4 pages of supplemental material, accepted to Physical Review E: Rapid Communication

Length-weight relationships and relative condition factor of Parapenaeopsis sculptilis (Heller, 1862) from the coastal waters of Perak, Peninsular Malaysia

Length-weight relationship (LWR) parameters and relative condition factor (K n) of marine shrimp, Parapenaeopsis sculptilis (Heller, 1862) were estimated using length-weight data collected between February 2012 and January 2013 from the coastal waters of Terong, Perak, Peninsular Malaysia. The estimated length-weight relationship of P. sculptilis for both sexes was W = 0.00027TL2.80. Meanwhile, the estimated relative growth coefficient (b) was 2.80 for both sexes, indicating a negative allometric growth pattern of P. sculptilis in the investigated area. Relative condition factor (Kn) values ranged from 0.99 to 1.064 (1.013±0.005, mean ±SD). Kn value changes in various months: the highest peak was in March-April, indicating the spawning period and the trough and small peaks indicating the cycle gonadal development

Direct entropy determination and application to artificial spin ice

From thermodynamic origins, the concept of entropy has expanded to a range of statistical measures of uncertainty, which may still be thermodynamically significant. However, laboratory measurements of entropy continue to rely on direct measurements of heat. New technologies that can map out myriads of microscopic degrees of freedom suggest direct determination of configurational entropy by counting in systems where it is thermodynamically inaccessible, such as granular and colloidal materials, proteins and lithographically fabricated nanometre-scale arrays. Here, we demonstrate a conditional-probability technique to calculate entropy densities of translation-invariant states on lattices using limited configuration data on small clusters, and apply it to arrays of interacting nanometre-scale magnetic islands (artificial spin ice). Models for statistically disordered systems can be assessed by applying the method to relative entropy densities. For artificial spin ice, this analysis shows that nearest-neighbour correlations drive longer-range ones.Comment: 10 page

Population dynamics of sergestid shrimps Acetes japonicus in the estuary of Tanjung Dawai, Kedah, Malaysia

Population parameters of male and female A. japonicus were studied using the monthly length frequency data to evaluate the mortality rates and its exploitation level. The sex ratio (male: Female) was found at 1: 0.94. Asymptotic length (L∞) was 25.20 mm and 28.88 mm for male and female, respectively. Growth co-efficient (K) for males and females was estimated at 1.80 and 1.30 year-1, respectively. Total mortality (Z) was calculated at 5.98 and 4.44 year-1 for male and female of A. japonicus respectively. Natural mortality (M) was 2.82 and 2.19 year-1 for the male and female shrimps. The fishing mortality (F) was 3.16 year-1 for male and 2.25 year-1 for female. Exploitation level (E) for male and female of A. japonicus was calculated at 0.53 and 0.51. The exploitation level was slightly over (E>0.50) the optimum level of exploitation (p = 0.50). The stock of A. japonicus was found to be slightly over exploited in Tanjung Dawai estuarine waters

Association between coronavirus cases and seasonal climatic variables in Mediterranean European Region, evidence by panel data regression

The coronavirus pandemic is one of the most fast-spreading diseases in the history, and the transmission of this virus has crossed rapidly over the whole world. In this study, we intend to detect the effect of temperature, precipitation, and wind speed on the Coronavirus infected cases throughout climate seasons for the whole year of epidemic starting from February 20, 2020 to February 19, 2021 with considering data patterns of each season separately; winter, spring, summer, autumn, in Mediterranean European regions, whereas those are located at the similar temperature zone in southern Europe. We apply the panel data approach by considering the developed robust estimation of clustered standard error which leads to achieving high forecasting accuracy. The main finding supports that temperature and wind speed have significant influence in reducing the Coronavirus cases at the beginning of this epidemic particularly in the first-winter, spring, and early summer, but they have very weak effects in the autumn and second-winter. Therefore, it is important to take into account the changes throughout seasons, and to consider other indirect factors which influence the virus transmission. This finding could lead to significant contributions to policymakers in European Union and European Commission Environment to limit the Coronavirus transmissions. As the Mediterranean region becomes more crowded for tourism purposes particularly in the summer season

Diet composition and feeding habits of Acetes japonicus (Decapoda: Sergestidae) in estuarine waters of Tanjung Dawai, Kedah, Malaysia

This study describes the diet composition and feeding habits of sergestid shrimps Acetes japonicas. The stomach contents of 330 specimens, captured from the Estuary of Tanjung Dawai, Kedah from June 2008 - May 2009 were analysed. Analysis on the percentage of numerical abundance (Ci) showed that plant matter (28.18%) and crustacean appendages (18.70%) as the two highest values amongst the eight categories of feeding items. In addition, percentage frequency of occurrence (Fpi) values of phytoplankton, zooplankton, algae, plant matter, appendages of crustacean, debris, unidentified items and sand-mud were 3.54%, 7.05%, 5.07%, 27.44%, 17.42%, 15.80%, 8.94% and 19.81% respectively. Based on the food composition found in the stomach, it could be concluded that A. japonicus is a bottom feeder omnivorous

Extended Reality Language Research: Data Sources, Taxonomy and the Documentation of Embodied Corpora

This article introduces extended reality linguistics, an emerging interdisciplinary field that explores the use of extended reality technologies in the scientific study of language. It delves into a variety of data sources for language study accessible through extended reality and showcases the advancements in data collection, visualization and analysis that this technology and its unique properties offer linguistic researchers. A comprehensive taxonomy of extended reality data is also presented, along with a survey of its applications in recent linguistic studies, offering further insights into the potential implications for future work. The article culminates in a pilot report on CEERR, an ongoing extended reality corpus linguistic project. This report highlights the innovative concepts of virtual linguistic fieldwork, communicative event reconstruction and embodied linguistic corpora. The CEERR pilot corpus demonstrates the powerful potential of extended reality for language documentation, prompting consideration of new grounds that traverse previous boundaries of language research data

Diagnosis of neuronal ceroid lipofuscinosis type 2 (CLN2 disease): Expert recommendations for early detection and laboratory diagnosis

Neuronal ceroid lipofuscinoses (NCLs) are a heterogeneous group of lysosomal storage disorders. NCLs include the rare autosomal recessive neurodegenerative disorder neuronal ceroid lipofuscinosis type 2 (CLN2) disease, caused by mutations in the tripeptidyl peptidase 1 (TPP1)/CLN2 gene and the resulting TPP1 enzyme deficiency. CLN2 disease most commonly presents with seizures and/or ataxia in the late-infantile period (ages 2-4), often in combination with a history of language delay, followed by progressive childhood dementia, motor and visual deterioration, and early death. Atypical phenotypes are characterized by later onset and, in some instances, longer life expectancies. Early diagnosis is important to optimize clinical care and improve outcomes; however, currently, delays in diagnosis are common due to low disease awareness, nonspecific clinical presentation, and limited access to diagnostic testing in some regions. In May 2015, international experts met to recommend best laboratory practices for early diagnosis of CLN2 disease. When clinical signs suggest an NCL, TPP1 enzyme activity should be among the first tests performed (together with the palmitoyl-protein thioesterase enzyme activity assay to rule out CLN1 disease). However, reaching an initial suspicion of an NCL or CLN2 disease can be challenging; thus, use of an epilepsy gene panel for investigation of unexplained seizures in the late-infantile/childhood ages is encouraged. To confirm clinical suspicion of CLN2 disease, the recommended gold standard for laboratory diagnosis is demonstration of deficient TPP1 enzyme activity (in leukocytes, fibroblasts, or dried blood spots) and the identification of causative mutations in each allele of the TPP1/CLN2 gene. When it is not possible to perform both analyses, either demonstration of a) deficient TPP1 enzyme activity in leukocytes or fibroblasts, or b) detection of two pathogenic mutations in trans is diagnostic for CLN2 disease

Genetic and phenotypic characterization of NKX6‐2‐related spastic ataxia and hypomyelination

Background and purpose Hypomyelinating leukodystrophies are a heterogeneous group of genetic disorders with a wide spectrum of phenotypes and a high rate of genetically unsolved cases. Bi‐allelic mutations in NKX6‐2 were recently linked to spastic ataxia 8 with hypomyelinating leukodystrophy. Methods Using a combination of homozygosity mapping, exome sequencing, and detailed clinical and neuroimaging assessment a series of new NKX6‐2 mutations in a multicentre setting is described. Then, all reported NKX6‐2 mutations and those identified in this study were combined and an in‐depth analysis of NKX6‐2‐related disease spectrum was provided. Results Eleven new cases from eight families of different ethnic backgrounds carrying compound heterozygous and homozygous pathogenic variants in NKX6‐2 were identified, evidencing a high NKX6‐2 mutation burden in the hypomyelinating leukodystrophy disease spectrum. Our data reveal a phenotype spectrum with neonatal onset, global psychomotor delay and worse prognosis at the severe end and a childhood onset with mainly motor phenotype at the milder end. The phenotypic and neuroimaging expression in NKX6‐2 is described and it is shown that phenotypes with epilepsy in the absence of overt hypomyelination and diffuse hypomyelination without seizures can occur. Conclusions NKX6‐2 mutations should be considered in patients with autosomal recessive, very early onset of nystagmus, cerebellar ataxia with hypotonia that rapidly progresses to spasticity, particularly when associated with neuroimaging signs of hypomyelination. Therefore, it is recommended that NXK6‐2 should be included in hypomyelinating leukodystrophy and spastic ataxia diagnostic panels