Crystal structure of 6-(2-fluorophenyl)-3-phenyl-[1,2,4]-triazolo[3,4-b][1,3,4]thiadiazole, C15H9FN4S

Abstract C15H9FN4S, orthorhombic, Pna21 (no. 33), a = 18.9361(2) Å, b = 11.5248(1) Å, c = 6.0142(1) Å, V = 1312.52(3) Å3, Z = 4, R gt (F) = 0.0263, wR ref (F 2 ) = 0.0706, T = 100 K.</jats:p

Crystal structures of 4-phenylpiperazin-1-ium 6-chloro-5-ethyl-2,4-dioxopyrimidin-1-ide and 4-phenylpiperazin-1-ium 6-chloro-5-isopropyl-2,4-dioxopyrimidin-1-ide

The title molecular salts, C10H15N2+·C6H6ClN2O2−, (I), and C10H15N2+·C7H8ClN2O2−, (II), consist of 4-phenylpiperazin-1-ium cations with a 6-chloro-5-ethyl-2,4-dioxopyrimidin-1-ide anion in (I) and a 6-chloro-5-isopropyl-2,4-dioxopyrimidin-1-ide anion in (II). Salt (I) crystallizes with two independent cations and anions in the asymmetric unit. In the crystal structures of both salts, the ions are linked via N—H...O and N—H...N hydrogen bonds, forming sheets which are parallel to (100) in (I) and to (001) in (II). In (I), the sheets are linked via C—H...Cl hydrogen bonds, forming a three-dimensional framework

Thermoregulatory and Physiological Responses of Najdi Sheep Exposed to Environmental Heat Load Prevailing in Saudi Arabia

The objective of this study was to evaluate the thermoregulatory and physiological responses of Najdi rams raised under hot summer conditions prevailing in Kingdom Saudi Arabia. The core temperature (Tcore) showed circadian rhythm characterized by biphasic achrophases, which were associated with the feeding times during both seasons. Average daily Tcore was significantly (P<0.05) higher under hot summer conditions. However, the amplitudes of the rhythmic oscillation during winter and summer seasons were 0.85 and 0.56C, respectively. Rectal (Tre) and skin temperatures (Tsk) were significantly (P<0.05) higher under hot summer conditions and exhibited similar patterns during both seasons concurrent with the pattern of temperature humidity index (THI), reaching the maximum values late in the afternoon and the minimum values early in the morning. Respiratory rate (RR) and heart rate (HR) showed the same pattern of the thermal parameters and were significantly (P<0.05) higher under hot summer conditions. Serum concentrations of total protein, globulin, glucose, sodium and chloride were significantly (P<0.05) increased while those of albumin and calcium were decreased under hot summer conditions. The results obtained from this study indicate that hot summer conditions of Saudi Arabia is thermally stressful to Najdi rams. Therefore, Najdi sheep production under such conditions would require environmental and/or nutritional modification to alleviate the impact of heat stress

Crystal structure of 5-(adamantan-1-yl)-3-= (4-chloroanilino)methyl-2,3-dihydro-1,3,4-oxadiazole-2-thione, C19H22ClN3OS

Abstract C19H22ClN3OS, orthorhombic, P212121 (no. 19), a = 7.0418(2) Å, b = 10.8802(3) Å, c = 23.5506(6) Å, V = 1804.36(8) Å3, Z = 4, R gt (F) = 0.0413, wR ref (F 2 ) = 0.1110, T = 100 K.</jats:p

A Hybrid Time Series–Regression Model for Tuberculosis Forecasting in Resource-Limited Settings

Tuberculosis (TB) is still a serious public health issue in Sudan, especially in Gedaref State, because of limited medical facilities and inadequate disease reporting. This experiment develops a forecasting model by employing Seasonal Trend decomposition using LOESS (STL) and linear regression in combination, relying on the weekly tests to improve TB prediction. The model improves the accuracy of its forecasts by combining time series information with the details of the daily operations of the health system. Weekly data from Gedaref showed that the STL + regression approach performed better than ARIMA, reducing the root mean squared error (RMSE) from 2986.85 to 540.95, an improvement of about 81.9%. The model also remained flexible to fluctuations in testing volume. The findings illustrated that hybrid statistical methods have been proved to be reliable and practical in forecasting TB cases in situations where limited resources exist, providing a strong base for overseeing TB and other communicable diseases

Saudi Arabia and its Gulf Co-operation Council neighbours : a study in international boundary management.

SIGLEAvailable from British Library Document Supply Centre-DSC:DXN042872 / BLDSC - British Library Document Supply CentreGBUnited Kingdo

Design principles for thermally comfortable and low energy homes in the extreme hot-humid climatic Gulf region, with reference to Dammam, Saudi Arabia

Indoor thermal comfort and its consequent energy consumption, are an increasingly important area of consideration in both developed and developing countries. The Gulf States, characterised by their composite extreme hot-humid climate and Airconditioning dependent society are renowned for their high energy consumption. The main aim of this research is to review and report on ways to enhance occupant thermal comfort in homes through improved building and system design and use that minimises energy consumption possible, in the extreme climate of Dammam, Saudi Arabia. The thesis does this by measuring and analysing the thermal performance of the buildings, the thermal satisfaction and comfort responses of their occupants and the energy consumption in them during August 2013 for the summer period and January 2014 for the winter period of the study. The comfort of occupants was assessed using the adaptive thermal comfort method. Neutral indoor air temperatures were, in several homes, surprisingly high. Moreover, most of the studied dwellings do not represent thermally comfortable homes as defined within either PMV or adaptive comfort limits. The study went on to review a broad range of factors that might strongly influence neutral temperatures indoors including the properties of the dwellings, occupant behaviours and attitudes towards high energy demand, loads and costs. The findings are discussed and conclusions drawn on individual design features that contribute to the comfort or discomfort experienced by occupants. It was found that lifestyle, attitudes and other socio-cultural factors have a clear influence on the comfort and in turn energy use in individual dwellings. Although several respondents did not sincerely care about the electricity as it is cheap, in late 2015 the Saudi government hiked the price of domestic energy bills by 60% as a result of low oil prices, putting pressure on many ordinary families to take more notice of their day to day living expenses. The recent electricity price hike provides an economic impetus for the design guidance proffered in the conclusions of this thesis to be taken seriously by householders and implemented by both them and regulating authorities in order to enhance domestic buildings and in turn reduce the CO2 emissions to the global atmosphere. The conclusion of this study is broadly applicable to other regions with similar climatic conditions and cultural contexts such as the Gulf countries

Atypical Presentation of Class II Lupus Nephritis

2021 clinical vignette posterhttps://digitalcommons.library.uab.edu/uabh-rd-all/1189/thumbnail.jp

Maximum Likelihood Estimation in the Inverse Weibull Distribution with Type II Censored Data

We consider maximum likelihood estimation for the parameters and certain functions of the parameters in the Inverse Weibull (IW) distribution based on type II censored data. The functions under consideration are the Mean Residual Life (MRL), which is very important in reliability studies, and Tail Value at Risk (TVaR), which is an important measure of risk in actuarial studies. We investigated the performance of the MLE of the parameters and derived functions under various experimental conditions using simulation techniques. The performance criteria are the bias and the mean squared error of the estimators. Recommendations on the use of the MLE in this model are given. We found that the parameter estimators are almost unbiased, while the MRL and TVaR estimators are asymptotically unbiased. Moreover, the mean squared error of all estimators decreased for larger sample sizes and it increased when the censoring proportion is increased for a fixed sample size. The conclusion is that the maximum likelihood method of estimation works well for the parameters and the derived functions of the parameter like the MRL and TVaR. Two examples on a real data set are presented to illustrate the application of the methods used in this paper. The first one is on survival time of pigs while the other is on fire losses.The authors would like to thank the referees for their suggestions and thoughtful comments that resulted in a much-improved version of the paper. This research was supported by a grant from the Office of Research Support at Qatar University, Grant no. QUST-1-CAS-2022-318