1,066 research outputs found
Renormalization-group approach to superconductivity: from weak to strong electron-phonon coupling
We present the numerical solution of the renormalization group (RG) equations
derived in Ref. [1], for the problem of superconductivity in the presence of
both electron-electron and electron-phonon coupling at zero temperature. We
study the instability of a Fermi liquid to a superconductor and the RG flow of
the couplings in presence of retardation effects and the crossover from weak to
strong coupling. We show that our numerical results provide an ansatz for the
analytic solution of the problem in the asymptotic limits of weak and strong
coupling.Comment: 8 pages, 3 figures, conference proceedings for the Electron
Correlations and Materials Properties, in Kos, Greece, July 5-9, 200
Syntaxin 16 is a master recruitment factor for cytokinesis
Recently it was shown that both recycling endosome and endosomal sorting complex required for transport (ESCRT) components are required for cytokinesis, in which they are believed to act in a sequential manner to bring about secondary ingression and abscission, respectively. However, it is not clear how either of these complexes is targeted to the midbody and whether their delivery is coordinated. The trafficking of membrane vesicles between different intracellular organelles involves the formation of soluble N-ethylmaleimide–sensitive factor attachment protein receptor (SNARE) complexes. Although membrane traffic is known to play an important role in cytokinesis, the contribution and identity of intracellular SNAREs to cytokinesis remain unclear. Here we demonstrate that syntaxin 16 is a key regulator of cytokinesis, as it is required for recruitment of both recycling endosome–associated Exocyst and ESCRT machinery during late telophase, and therefore that these two distinct facets of cytokinesis are inextricably linked
Tuning a Circular p-n Junction in Graphene from Quantum Confinement to Optical Guiding
The motion of massless Dirac-electrons in graphene mimics the propagation of
photons. This makes it possible to control the charge-carriers with components
based on geometrical-optics and has led to proposals for an all-graphene
electron-optics platform. An open question arising from the possibility of
reducing the component-size to the nanometer-scale is how to access and
understand the transition from optical-transport to quantum-confinement. Here
we report on the realization of a circular p-n junction that can be
continuously tuned from the nanometer-scale, where quantum effects are
dominant, to the micrometer scale where optical-guiding takes over. We find
that in the nanometer-scale junction electrons are trapped in states that
resemble atomic-collapse at a supercritical charge. As the junction-size
increases, the transition to optical-guiding is signaled by the emergence of
whispering-gallery modes and Fabry-Perot interference. The creation of tunable
junctions that straddle the crossover between quantum-confinement and
optical-guiding, paves the way to novel design-architectures for controlling
electronic transport.Comment: 16 pages, 4 figure
Giant Faraday rotation in single- and multilayer graphene
Optical Faraday rotation is one of the most direct and practically important
manifestations of magnetically broken time-reversal symmetry. The rotation
angle is proportional to the distance traveled by the light, and up to now
sizeable effects were observed only in macroscopically thick samples and in
two-dimensional electron gases with effective thicknesses of several
nanometers. Here we demonstrate that a single atomic layer of carbon - graphene
- turns the polarization by several degrees in modest magnetic fields. The
rotation is found to be strongly enhanced by resonances originating from the
cyclotron effect in the classical regime and the inter-Landau-level transitions
in the quantum regime. Combined with the possibility of ambipolar doping, this
opens pathways to use graphene in fast tunable ultrathin infrared
magneto-optical devices
Emergent Phenomena Induced by Spin-Orbit Coupling at Surfaces and Interfaces
Spin-orbit coupling (SOC) describes the relativistic interaction between the
spin and momentum degrees of freedom of electrons, and is central to the rich
phenomena observed in condensed matter systems. In recent years, new phases of
matter have emerged from the interplay between SOC and low dimensionality, such
as chiral spin textures and spin-polarized surface and interface states. These
low-dimensional SOC-based realizations are typically robust and can be
exploited at room temperature. Here we discuss SOC as a means of producing such
fundamentally new physical phenomena in thin films and heterostructures. We put
into context the technological promise of these material classes for developing
spin-based device applications at room temperature
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Applicability of an 'uptake wave' energy transition concept in Indian households
Abstract
Reliable, secure, and affordable energy services are essential to ensuring sustainable economic and social development in the rapidly growing cities of the Global South, yet in India over 30 percent of urban households are still reliant on traditional fuels such as biomass and kerosene for some portion of their energy needs. Understanding the factors that influence energy transitions at a household level, is essential for successful strategies to promote the uptake of cleaner fuels and deliver associated socio-economic benefits. Such fast-growing cities often display intra-urban inequalities of considerable magnitude which can condition individual access to resources and impact the effectiveness of energy provision strategies for individual city districts. In this paper we will use the results of a survey of 500 households in Bangalore, India and explore how this data compares with the ‘wave concept’ model of energy transition. This ‘wave concept’ view of energy transitions focuses on appliance ownership as a proxy for energy services and conceptualises the uptake of appliances as a wave with early and late adopters rather than an income-based step change, and as a result better accounts for the role of non-income factors. The wards targeted by the survey cover a range of low-income ward typologies characterised by factors including income, livelihoods, building construction, socio-cultural factors, access to fuels, and reliability of supply. Validating an appropriate model for the uptake of new energy technologies and fuels in households, can better inform policy makers, entrepreneurs, and engineers on the influence of non-income barriers to energy transition across different districts of a city. By understanding how households use energy, and what limits the adoption of more efficient technologies at a local level, city planners and engineers can develop targeted sustainable strategies for adoption of cleaner more efficient fuels and appliances in households.</jats:p
Graphene plasmonics
Two rich and vibrant fields of investigation, graphene physics and
plasmonics, strongly overlap. Not only does graphene possess intrinsic plasmons
that are tunable and adjustable, but a combination of graphene with noble-metal
nanostructures promises a variety of exciting applications for conventional
plasmonics. The versatility of graphene means that graphene-based plasmonics
may enable the manufacture of novel optical devices working in different
frequency ranges, from terahertz to the visible, with extremely high speed, low
driving voltage, low power consumption and compact sizes. Here we review the
field emerging at the intersection of graphene physics and plasmonics.Comment: Review article; 12 pages, 6 figures, 99 references (final version
available only at publisher's web site
Application of Graphene within Optoelectronic Devices and Transistors
Scientists are always yearning for new and exciting ways to unlock graphene's
true potential. However, recent reports suggest this two-dimensional material
may harbor some unique properties, making it a viable candidate for use in
optoelectronic and semiconducting devices. Whereas on one hand, graphene is
highly transparent due to its atomic thickness, the material does exhibit a
strong interaction with photons. This has clear advantages over existing
materials used in photonic devices such as Indium-based compounds. Moreover,
the material can be used to 'trap' light and alter the incident wavelength,
forming the basis of the plasmonic devices. We also highlight upon graphene's
nonlinear optical response to an applied electric field, and the phenomenon of
saturable absorption. Within the context of logical devices, graphene has no
discernible band-gap. Therefore, generating one will be of utmost importance.
Amongst many others, some existing methods to open this band-gap include
chemical doping, deformation of the honeycomb structure, or the use of carbon
nanotubes (CNTs). We shall also discuss various designs of transistors,
including those which incorporate CNTs, and others which exploit the idea of
quantum tunneling. A key advantage of the CNT transistor is that ballistic
transport occurs throughout the CNT channel, with short channel effects being
minimized. We shall also discuss recent developments of the graphene tunneling
transistor, with emphasis being placed upon its operational mechanism. Finally,
we provide perspective for incorporating graphene within high frequency
devices, which do not require a pre-defined band-gap.Comment: Due to be published in "Current Topics in Applied Spectroscopy and
the Science of Nanomaterials" - Springer (Fall 2014). (17 pages, 19 figures
High intake of phytoestrogens and precocious thelarche: case report with a possible correlation
Precocious thelarche is the breast development before 8 years of age with two peaks of incidence during the first two years of life and after 6 years of age. A 4.75-year-old girl presented with thelarche associated to an excessive intake of phytoestrogens (phye). Tanner development B2P1-2, hormonal levels and pelvic US were compatible with peripheral precocious puberty. During follow-up, a daily intake of soy-based foods was observed (> 40 mg phye/day). Soy is rich in phytoestrogens, mainly genistein and daidzein. Although phye are less strong than estradiol, its concentration could be from 13,000 to 22,000 times stronger in children fed only by soy-based formulas. Parents were advised and soy intake was reduced to once a week. Progression of pubertal development ceased at B2-3P1. The patient, now 8.66 years old, keeps growing with similar bone and chronological ages. Some questions related to industrial food security, mainly the soy-based food, remain without precise answer. Although it is well known the entity of non-progressive precocious puberty and premature thelarche, pubertal development in this case was strongly related to excessive daily intake of soy and other phye-rich food that could trigger puberty as endocrine disruptor.Telarca precoce, desenvolvimento mamário antes dos 8 anos de idade, apresenta dois picos de incidência, nos dois primeiros anos de vida e após os 6 anos de idade. Uma menina de 4,75 anos apresentou-se com telarca associada à ingestão excessiva de fitoestrógenos. O desenvolvimento puberal M2P1-2, os níveis hormonais e o US pélvico eram compatíveis com puberdade precoce periférica. Durante o seguimento, observou-se ingestão diária de alimentos baseados em soja (> 40 mg fitoestrógenos/dia). Soja contém fitoestrógenos, principalmente genisteína e daidzeína. Embora menos potentes do que o estradiol, sua concentração pode ser 13.000 a 22.000 vezes maior em crianças alimentadas somente com fórmulas baseadas em soja. Os pais foram aconselhados a reduzir para uma vez na semana o seu fornecimento na dieta. O desenvolvimento puberal cessou em M2-3P1 e a paciente, com 8,66 anos, continua a desenvolver-se com idades óssea e cronológica equivalentes. Questões relacionadas à segurança alimentar, principalmente de alimentos baseados em soja, permanecem sem respostas precisas. Embora sejam conhecidas as etiologias da puberdade precoce não progressiva e da telarca prematura, neste caso esteve fortemente relacionada à ingestão excessiva de soja e de outros alimentos ricos em fitoestrógenos que poderiam ter desencadeado a telarca atuando como desreguladores endócrinos.Universidade Federal de São Paulo (UNIFESP) Escola Paulista de Medicina Departamento de MedicinaUNIFESP, EPM, Depto. de MedicinaSciEL
T-Cell Memory Responses Elicited by Yellow Fever Vaccine are Targeted to Overlapping Epitopes Containing Multiple HLA-I and -II Binding Motifs
The yellow fever vaccines (YF-17D-204 and 17DD) are considered to be among the safest vaccines and the presence of neutralizing antibodies is correlated with protection, although other immune effector mechanisms are known to be involved. T-cell responses are known to play an important role modulating antibody production and the killing of infected cells. However, little is known about the repertoire of T-cell responses elicited by the YF-17DD vaccine in humans. In this report, a library of 653 partially overlapping 15-mer peptides covering the envelope (Env) and nonstructural (NS) proteins 1 to 5 of the vaccine was utilized to perform a comprehensive analysis of the virus-specific CD4+ and CD8+ T-cell responses. The T-cell responses were screened ex-vivo by IFN-γ ELISPOT assays using blood samples from 220 YF-17DD vaccinees collected two months to four years after immunization. Each peptide was tested in 75 to 208 separate individuals of the cohort. The screening identified sixteen immunodominant antigens that elicited activation of circulating memory T-cells in 10% to 33% of the individuals. Biochemical in-vitro binding assays and immunogenetic and immunogenicity studies indicated that each of the sixteen immunogenic 15-mer peptides contained two or more partially overlapping epitopes that could bind with high affinity to molecules of different HLAs. The prevalence of the immunogenicity of a peptide in the cohort was correlated with the diversity of HLA-II alleles that they could bind. These findings suggest that overlapping of HLA binding motifs within a peptide enhances its T-cell immunogenicity and the prevalence of the response in the population. In summary, the results suggests that in addition to factors of the innate immunity, "promiscuous" T-cell antigens might contribute to the high efficacy of the yellow fever vaccines. © 2013 de Melo et al
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