5,735 research outputs found
Online Professional Learning Communities as Sites for Learning and Connection: Teacher Agency and the Rhizome
This paper responds to the themes of learning and connected communities and technology enhanced learning. It explores the relationship between teacher agency and online Professional Learning Communities (PLCs) – specifically the use of social media tools among trainee teachers. Using a discourse analysis methodology we present the early experiences and reflections of the curriculum development team and trainee teachers as we seek to integrate social media, both formally and informally into a distance-learning environment, merging the best practices of face-to-face and blended learning. The site of learning is a distance learning Postgraduate Certificate in Education (PGCE) provided by a large University in the North of England. This Master’s level course enhances the practice-based development of trainee teachers (leading to Qualified Teacher Status). It provides opportunities for trainee teachers to create and share knowledge, and to connect with educational theory, evidence informed research and pedagogical content knowledge (PCK). Originally established as face-to-face and blended provision, the curriculum development team has moved towards distance learning, and two cohorts are currently enrolled, constituted of 75 students. The University works in partnership with School Based Initial Teacher Training providers (SCITTs). The curriculum architecture of this PGCE is premised upon notions of Heutagogy, Rhizomatic Learning and Instructional Design. It embeds Master’s level attributes, promoting self-determined learning, high levels of autonomy, epistemic curiosity and a willingness to engage and participate. The affordances of social media tools supports the creation of learner-generated content, and emerging communities of practice, facilitated and moderated by several agents, including the curriculum team, the trainee teachers, and their mentors. We reflect on our ongoing research into participation in constructed and facilitated Professional Learning Communities. This paper contributes to debates surrounding heutagogy, PLCs, instructional design, and non-participation. It will be of interest to academics and practitioners seeking to debate social media in education and curriculum development, whether for blended, online or distance learning
Fermentation kinetics including product and substrate inhibitions plus biomass death: a mathematical analysis
Fermentation is generally modelled by kinetic equations giving the time
evolutions for biomass, substrate, and product concentrations. Although these
equations can be solved analytically in simple cases if substrate/product
inhibition and biomass death are included, they are typically solved
numerically. We propose an analytical treatment of the kinetic equations
--including cell death and an arbitrary number of inhibitions-- in which
constant yield needs not be assumed. Equations are solved in phase space, i.e.
the biomass concentration is written explicitly as a function of the substrate
concentration.Comment: 4 pages, 4 figure
Potentiality in Biology
We take the potentialities that are studied in the biological sciences (e.g., totipotency) to be an important subtype of biological dispositions. The goal of this paper is twofold: first, we want to provide a detailed understanding of what biological dispositions are. We claim that two features are essential for dispositions in biology: the importance of the manifestation process and the diversity of conditions that need to be satisfied for the disposition to be manifest. Second, we demonstrate that the concept of a disposition (or potentiality) is a very useful tool for the analysis of the explanatory practice in the biological sciences. On the one hand it allows an in-depth analysis of the nature and diversity of the conditions under which biological systems display specific behaviors. On the other hand the concept of a disposition may serve a unificatory role in the philosophy of the natural sciences since it captures not only the explanatory practice of biology, but of all natural sciences. Towards the end we will briefly come back to the notion of a potentiality in biology
Entanglement-free Heisenberg-limited phase estimation
Measurement underpins all quantitative science. A key example is the
measurement of optical phase, used in length metrology and many other
applications. Advances in precision measurement have consistently led to
important scientific discoveries. At the fundamental level, measurement
precision is limited by the number N of quantum resources (such as photons)
that are used. Standard measurement schemes, using each resource independently,
lead to a phase uncertainty that scales as 1/sqrt(N) - known as the standard
quantum limit. However, it has long been conjectured that it should be possible
to achieve a precision limited only by the Heisenberg uncertainty principle,
dramatically improving the scaling to 1/N. It is commonly thought that
achieving this improvement requires the use of exotic quantum entangled states,
such as the NOON state. These states are extremely difficult to generate.
Measurement schemes with counted photons or ions have been performed with N <=
6, but few have surpassed the standard quantum limit and none have shown
Heisenberg-limited scaling. Here we demonstrate experimentally a
Heisenberg-limited phase estimation procedure. We replace entangled input
states with multiple applications of the phase shift on unentangled
single-photon states. We generalize Kitaev's phase estimation algorithm using
adaptive measurement theory to achieve a standard deviation scaling at the
Heisenberg limit. For the largest number of resources used (N = 378), we
estimate an unknown phase with a variance more than 10 dB below the standard
quantum limit; achieving this variance would require more than 4,000 resources
using standard interferometry. Our results represent a drastic reduction in the
complexity of achieving quantum-enhanced measurement precision.Comment: Published in Nature. This is the final versio
Signature of effective mass in crackling noise asymmetry
Crackling noise is a common feature in many dynamic systems [1-9], the most
familiar instance of which is the sound made by a sheet of paper when crumpled
into a ball. Although seemingly random, this noise contains fundamental
information about the properties of the system in which it occurs. One
potential source of such information lies in the asymmetric shape of noise
pulses emitted by a diverse range of noisy systems [8-12], but the cause of
this asymmetry has lacked explanation [1]. Here we show that the leftward
asymmetry observed in the Barkhausen effect [2] - the noise generated by the
jerky motion of domain walls as they interact with impurities in a soft magnet
- is a direct consequence of a magnetic domain wall's negative effective mass.
As well as providing a means of determining domain wall effective mass from a
magnet's Barkhausen noise our work suggests an inertial explanation for the
origin of avalanche asymmetries in crackling noise phenomena more generally.Comment: 13 pages, 4 figures, to appear in Nature Physic
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The rise of the quasi-public space and its consequences for cities and culture
This article argues that whilst appearing new, quasi-public spaces have emerged from a process of investment restructuring over the last 50 years. The profound change that is set in motion is a loss of control of public space and its cultural uses in cities. The tensions set up in this transformation are illustrated by the cultural fortunes of the largest such space in London, Granary Square; and, that of the City of London that has little, if any, public space
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Possible impacts of a future grand solar minimum on climate: Stratospheric and global circulation changes
It has been suggested that the Sun may evolve into a period of lower activity over the 21st century. This study examines the potential climate impacts of the onset of an extreme “Maunder Minimum-like” grand solar minimum using a comprehensive global climate model. Over the second half of the 21st century, the scenario assumes a decrease in total solar irradiance of 0.12% compared to a reference Representative Concentration Pathway 8.5 experiment. The decrease in solar irradiance cools the stratopause (∼1 hPa) in the annual and global mean by 1.2 K. The impact on global mean near-surface temperature is small (∼−0.1 K), but larger changes in regional climate occur during the stratospheric dynamically active seasons. In Northern Hemisphere wintertime, there is a weakening of the stratospheric westerly jet by up to ∼3–4 m s−1, with the largest changes occurring in January–February. This is accompanied by a deepening of the Aleutian Low at the surface and an increase in blocking over Northern Europe and the North Pacific. There is also an equatorward shift in the Southern Hemisphere midlatitude eddy-driven jet in austral spring. The occurrence of an amplified regional response during winter and spring suggests a contribution from a top-down pathway for solar-climate coupling; this is tested using an experiment in which ultraviolet (200–320 nm) radiation is decreased in isolation of other changes. The results show that a large decline in solar activity over the 21st century could have important impacts on the stratosphere and regional surface climate
Redox linked flavin sites in extracellular decaheme proteins involved in microbe-mineral electron transfer
Extracellular microbe-mineral electron transfer is a major driving force for the oxidation of organic carbon in many subsurface environments. Extracellular multi-heme cytochromes of the Shewenella genus play a major role in this process but the mechanism of electron exchange at the interface between cytochrome and acceptor is widely debated. The 1.8 Å x-ray crystal structure of the decaheme MtrC revealed a highly conserved CX8C disulfide that, when substituted for AX8A, severely compromised the ability of S. oneidensis to grow under aerobic conditions. Reductive cleavage of the disulfide in the presence of flavin mononucleotide (FMN) resulted in the reversible formation of a stable flavocytochrome. Similar results were also observed with other decaheme cytochromes, OmcA, MtrF and UndA. The data suggest that these decaheme cytochromes can transition between highly reactive flavocytochromes or less reactive cytochromes, and that this transition is controlled by a redox active disulfide that responds to the presence of oxygen
Effect of Biodiversity Changes in Disease Risk: Exploring Disease Emergence in a Plant-Virus System
The effect of biodiversity on the ability of parasites to infect their host and cause disease (i.e. disease risk) is a major question in pathology, which is central to understand the emergence of infectious diseases, and to develop strategies for their management. Two hypotheses, which can be considered as extremes of a continuum, relate biodiversity to disease risk: One states that biodiversity is positively correlated with disease risk (Amplification Effect), and the second predicts a negative correlation between biodiversity and disease risk (Dilution Effect). Which of them applies better to different host-parasite systems is still a source of debate, due to limited experimental or empirical data. This is especially the case for viral diseases of plants. To address this subject, we have monitored for three years the prevalence of several viruses, and virus-associated symptoms, in populations of wild pepper (chiltepin) under different levels of human management. For each population, we also measured the habitat species diversity, host plant genetic diversity and host plant density. Results indicate that disease and infection risk increased with the level of human management, which was associated with decreased species diversity and host genetic diversity, and with increased host plant density. Importantly, species diversity of the habitat was the primary predictor of disease risk for wild chiltepin populations. This changed in managed populations where host genetic diversity was the primary predictor. Host density was generally a poorer predictor of disease and infection risk. These results support the dilution effect hypothesis, and underline the relevance of different ecological factors in determining disease/infection risk in host plant populations under different levels of anthropic influence. These results are relevant for managing plant diseases and for establishing conservation policies for endangered plant species
Emergency ambulance service involvement with residential care homes in the support of older people with dementia : an observational study
© 2014 Amador et al.; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.BACKGROUND: Older people resident in care homes have a limited life expectancy and approximately two-thirds have limited mental capacity. Despite initiatives to reduce unplanned hospital admissions for this population, little is known about the involvement of emergency services in supporting residents in these settings.METHODS: This paper reports on a longitudinal study that tracked the involvement of emergency ambulance personnel in the support of older people with dementia, resident in care homes with no on-site nursing providing personal care only. 133 residents with dementia across 6 care homes in the East of England were tracked for a year. The paper examines the frequency and reasons for emergency ambulance call-outs, outcomes and factors associated with emergency ambulance service use. RESULTS: 56% of residents used ambulance services. Less than half (43%) of all call-outs resulted in an unscheduled admission to hospital. In addition to trauma following a following a fall in the home, results suggest that at least a reasonable proportion of ambulance contacts are for ambulatory care sensitive conditions. An emergency ambulance is not likely to be called for older rather than younger residents or for women more than men. Length of residence does not influence use of emergency ambulance services among older people with dementia. Contact with primary care services and admission route into the care home were both significantly associated with emergency ambulance service use. The odds of using emergency ambulance services for residents admitted from a relative's home were 90% lower than the odds of using emergency ambulance services for residents admitted from their own home. CONCLUSIONS: Emergency service involvement with this vulnerable population merits further examination. Future research on emergency ambulance service use by older people with dementia in care homes, should account for important contextual factors, namely, presence or absence of on-site nursing, GP involvement, and access to residents' family, alongside resident health characteristics.Peer reviewedFinal Published versio
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