46 research outputs found
Two classes of nonlocal Evolution Equations related by a shared Traveling Wave Problem
We consider reaction-diffusion equations and Korteweg-de Vries-Burgers (KdVB)
equations, i.e. scalar conservation laws with diffusive-dispersive
regularization. We review the existence of traveling wave solutions for these
two classes of evolution equations. For classical equations the traveling wave
problem (TWP) for a local KdVB equation can be identified with the TWP for a
reaction-diffusion equation. In this article we study this relationship for
these two classes of evolution equations with nonlocal diffusion/dispersion.
This connection is especially useful, if the TW equation is not studied
directly, but the existence of a TWS is proven using one of the evolution
equations instead. Finally, we present three models from fluid dynamics and
discuss the TWP via its link to associated reaction-diffusion equations
A Software Tool to Model Genetic Regulatory Networks. Applications to the Modeling of Threshold Phenomena and of Spatial Patterning in Drosophila
We present a general methodology in order to build mathematical models of genetic regulatory networks. This approach is based on the mass action law and on the Jacob and Monod operon model. The mathematical models are built symbolically by the Mathematica software package GeneticNetworks. This package accepts as input the interaction graphs of the transcriptional activators and repressors of a biological process and, as output, gives the mathematical model in the form of a system of ordinary differential equations. All the relevant biological parameters are chosen automatically by the software. Within this framework, we show that concentration dependent threshold effects in biology emerge from the catalytic properties of genes and its associated conservation laws. We apply this methodology to the segment patterning in Drosophila early development and we calibrate the genetic transcriptional network responsible for the patterning of the gap gene proteins Hunchback and Knirps, along the antero-posterior axis of the Drosophila embryo. In this approach, the zygotically produced proteins Hunchback and Knirps do not diffuse along the antero-posterior axis of the embryo of Drosophila, developing a spatial pattern due to concentration dependent thresholds. This shows that patterning at the gap genes stage can be explained by the concentration gradients along the embryo of the transcriptional regulators
Front-like entire solutions for monostable reaction-diffusion systems
This paper is concerned with front-like entire solutions for monostable
reactiondiffusion systems with cooperative and non-cooperative nonlinearities.
In the cooperative case, the existence and asymptotic behavior of spatially
independent solutions (SIS) are first proved. Combining a SIS and traveling
fronts with different wave speeds and directions, the existence and various
qualitative properties of entire solutions are then established using
comparison principle. In the non-cooperative case, we introduce two auxiliary
cooperative systems and establish some comparison arguments for the three
systems. The existence of entire solutions is then proved via the traveling
fronts and SIS of the auxiliary systems. Our results are applied to some
biological and epidemiological models. To the best of our knowledge, it is the
first work to study the entire solutions of non-cooperative reaction-diffusion
systems
Uncertainty quantification in tsunami modeling using multi-level Monte Carlo finite volume method
Traveling Wave Solutions in a Generalized Theory for Macroscopic Capillarity
One-dimensional traveling wave solutions for imbibition processes into a homogeneous porous medium are found within a recent generalized theory of macroscopic capillarity. The generalized theory is based on the hydrodynamic differences between percolating and nonpercolating fluid parts. The traveling wave solutions are obtained using a dynamical systems approach. An exhaustive study of all smooth traveling wave solutions for primary and secondary imbibition processes is reported here. It is made possible by introducing two novel methods of reduced graphical representation. In the first method the integration constant of the dynamical system is related graphically to the boundary data and the wave velocity. In the second representation the wave velocity is plotted as a function of the boundary data. Each of these two graphical representations provides an exhaustive overview over all one-dimensional and smooth solutions of traveling wave type, that can arise in primary and secondary imbibition. Analogous representations are possible for other systems, solution classes, and processes.</p
