9 research outputs found
Differences between KC and KPC pancreatic ductal adenocarcinoma mice models, in terms of their modeling biology and their clinical relevance
No full textThe involvement of exosomes in the diagnosis and treatment of pancreatic cancer
No full textAbstractAt the moment, pancreatic cancer is among the deadliest gastrointestinal diseases, and pancreatic cancer growth is a complex biological process that is based on different kinds of genes. Exosomes are extracellular vesicles containing microRNAs (miRNAs), messenger RNA (mRNA), and proteins, they act as the most prominent mediator of intercellular communication, and they regulate, instruct, and re-educate their surrounding microenvironment and target specific organs. Due to accumulative evidence proved that exosomes are involved in metastasis, cell proliferation, EMT, angiogenesis, and TME of pancreatic cancer, exosomes are crucial potential candidates to detect pancreatic cancer early. This review aims to convey the current understanding of the main functions employed by exosomes in early diagnosis and treatment of pancreatic cancer.</jats:p
Efficacy of cycling interventions to improve function in children and adolescents with cerebral palsy: a systematic review and meta-analysis
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Bio-carrier and operating temperature effect on ammonia removal from secondary wastewater effluents using moving bed biofilm reactor (MBBR)
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