Laryngeal features are phonetically abstract : mismatch negativity evidence from Arabic, English, and Russian

2016-2017 > Academic research: refereed > Publication in refereed journal201804_a bcmaVersion of RecordPublishe

L'accompagnement infirmier du patient atteint de sclérose en plaques: travail de Bachelor

Le présent travail porte sur les déterminants de l’accompagnement infirmier à l’égard d’une personne atteinte de sclérose en plaques (SEP). La SEP est une maladie neurodégénérative, incurable et évolutive qui a des conséquences sur les sphères physiques, psychiques, sociales et spirituelles du patient, et par conséquent, elle requiert une prise en soin globale de la part de l’infirmière. Le traitement médicamenteux n’est pas suffisant pour ralentir l’évolution de cette affection, d’autres services de soins sont également nécessaires pour offrir du bien-être au patient. Les poussées de la SEP sont imprévisibles et l’évolution de cette pathologie est incertaine tout comme l’avenir du patient. De plus le patient subit plusieurs pertes liées à sa maladie et peut donc présenter une détresse psychologique liée à ces pertes. La notion « accompagnement » est, à l’heure actuelle, devenue une compétence qui comprend plusieurs qualités importantes que l’infirmière met en oeuvre au moment du diagnostic de la SEP et tout au long du chemin de vie du patient. L’accompagnement englobe diverses composantes telles que l’empathie, l’écoute, la compassion et le respect qui permettent entre autre d’offrir une bonne qualité d’accompagnement au patient. Ce travail met en lumière les dix facteurs caratifs de la théorie « Human Caring » proposée par Watson (1998). Ceux-ci sont mis en lien avec plusieurs situations concrètes relatives à la SEP. Ce travail met en lumière les éléments qui contribuent à une bonne prise en soins et favorisent un accompagnement vis-à-vis du patient atteint de SEP. Tous les facteurs caratifs pris en considération ne peuvent pas être considérés dans cette prise en charge, car certains d’entre eux constituent un idéal, mais demeurent difficiles à appliquer dans la réalité de la pratique professionnelle autour de la SEP. A l’issue de cette réflexion, il est recommandé aux soignants des unités de neurologie de réfléchir quant à la mise en place d’un outil permettant d’évaluer tous les besoins des patients atteints de SEP afin de pouvoir y répondre. La création d’une anamnèse complète ou d’un questionnaire sur les attentes des personnes vivant avec cette maladie serait-il envisageable pour le futur

Minimal Position-Velocity Uncertainty Wave Packets in Relativistic and Non-relativistic Quantum Mechanics

We consider wave packets of free particles with a general energy-momentum dispersion relation $E(p)$. The spreading of the wave packet is determined by the velocity v = \p_p E. The position-velocity uncertainty relation $\Delta x \Delta v \geq {1/2} ||$ is saturated by minimal uncertainty wave packets $\Phi(p) = A \exp(- \alpha E(p) + \beta p)$. In addition to the standard minimal Gaussian wave packets corresponding to the non-relativistic dispersion relation $E(p) = p^2/2m$, analytic calculations are presented for the spreading of wave packets with minimal position-velocity uncertainty product for the lattice dispersion relation $E(p) = - \cos(p a)/m a^2$ as well as for the relativistic dispersion relation $E(p) = \sqrt{p^2 + m^2}$. The boost properties of moving relativistic wave packets as well as the propagation of wave packets in an expanding Universe are also discussed

Measuring the Polarization of Boosted Hadronic Tops

We propose a new technique for measuring the polarization of hadronically decaying boosted top quarks. In particular, we apply a subjet-based technique to events where the decay products of the top are clustered within a single jet. The technique requires neither b-tagging nor W-reconstruction, and does not rely on assumptions about either the top production mechanism or the sources of missing energy in the event. We include results for various new physics scenarios made with different Monte Carlo generators to demonstrate the robustness of the technique.Comment: v2: version accepted for publication in JHE

Deficits in trabecular bone microarchitecture in young women with Type 1 diabetes mellitus

Context: The pathophysiological mechanism of increased fractures in young adults with Type 1 Diabetes Mellitus (T1DM) is unclear. Objective: Case:control study of trabecular bone microarchitecture and vertebral marrow adiposity in young women with T1DM. Patients and Settings: 30 women with T1DM with a median (range) age of 22.0yrs (16.9, 36.1) attending one outpatient clinic with a median age at diagnosis of 9.7yrs (0.46, 14.8) were compared to 28 age-matched healthy women who acted as controls. Methods and Main Outcome Measures: Measurements included MRI-based assessment of proximal tibial bone volume/total volume (appBV/TV), trabecular separation (appTb.Sp), vertebral bone marrow adiposity (BMA) and abdominal adipose tissue and biochemical markers of GH/IGF-1 axis (IGF-1, IGFBP3, ALS) and bone turnover. Results: Median appBV/TV in cases and controls was 0.3 (0.22, 0.37) and 0.33 (0.26, 0.4), respectively (p = 0.018) and median appTb.Sp in T1DM was 2.59 (2.24, 3.38) and 2.32 (2.03, 2.97), respectively (p = 0.012). The median appBV/TV was 0.28 (0.22, 0.33) in those cases with retinopathy (n,15) compared to 0.33 (0.25, 0.37) in those without retinopathy (p = 0.02). Although median visceral adipose tissue in cases was higher than in controls at 5,733mm3 (2030, 11,144) and 3,460mm3 (1,808, 6,832), respectively (p = 0.012), there was no difference in median BMA which was 31.1% (9.9, 59.9) and 26.3% (8.5, 49.8) in cases and controls, respectively (p = 0.2). Serum IGF-1 and ALS were also lower in cases and the latter showed an inverse association to appTbSp (r = -0.30, p = 0.04). Conclusion: Detailed MRI studies in young women with childhood-onset T1DM have shown clear deficits in trabecular microarchitecture of the tibia. Underlying pathophysiological mechanisms may include a microvasculopathy

Entanglement dynamics of two-bipartite system under the influence of dissipative environments

An experimental scheme is suggested that permits a direct measure of entanglement in a two-qubit cavity system. It is realized in the cavity-QED technology utilizing atoms as flying qubits. With this scheme we generate two different measures of entanglement, namely logarithmic negativity and concurrence. The phenomenon of sudden death entanglement (ESD) in a bipartite system subjected to dissipative environment is examined. We show that the sudden death time of the entangled states depends on the initial preparation of the entangled state and the temperature of the reservoir.Comment: 21 pages, 13 figure

Modulated Entanglement Evolution Via Correlated Noises

We study entanglement dynamics in the presence of correlated environmental noises. Specifically, we investigate the quantum entanglement dynamics of two spins in the presence of correlated classical white noises, deriving Markov master equation and obtaining explicit solutions for several interesting classes of initial states including Bell states and X form density matrices. We show how entanglement can be enhanced or reduced by the correlation between the two participating noises.Comment: 9 pages, 4 figures. To be published in Quantum Information Processing, special issue on Quantum Decoherence and Entanglemen

Transition-metal norharmane compounds as possible cytotoxic agents: new insights based on a coordination chemistry perspective

New first-row transition-metal compounds with the ligand norharmane (9H-Pyrido[3,4-b]indole; Hnor) are reported. The compounds have the general formula [M(LL)(Hnor)(NO3)2](MeOH)0–1 (M = Co, Ni, Cu, Zn; LL = 2,2′-bipyridyl (bpy), 1,10-phenanthroline (phen)) and have been characterized by physical and analytical methods. X-ray structural analysis revealed that the compound of formula [Cu(phen)(Hnor)(NO3)2], (1) has a distorted 6-coordinated octahedrally-based geometry, with a planar-based [CuN3O] core, where Cu-L varies between 1.99 and 2.04 Å and two weak axial Cusingle bondO contacts (2.209 and 2.644 Å) from two different nitrates. Based on spectroscopic similarities, the other compounds appear to have the same or very similar coordination geometries. The compounds showed clear cell growth inhibitory effects in two different cancer cell lines in vitro, with the copper and zinc complexes being the most toxic and in fact almost comparable to cisplatin. Flow-cytometry analysis confirmed induction of apoptosis in cancer cells treated with the compounds. Interestingly, co-incubation of the cells with metal complexes and CuCl2 induced an increase in the cytotoxic effects, most likely due to the conversion of the metal compounds in the corresponding, and most active, copper analogues