On design of robust fault detection filter in finite-frequency domain with regional pole assignment

This brief is concerned with the fault detection (FD) filter design problem for an uncertain linear discrete-time system in the finite-frequency domain with regional pole assignment. An optimized FD filter is designed such that: 1) the FD dynamics is quadratically D-stable; 2) the effect from the exogenous disturbance on the residual is attenuated with respect to a minimized H∞-norm; and 3) the sensitivity of the residual to the fault is enhanced by means of a maximized H--norm. With the aid of the generalized Kalman-Yakubovich-Popov lemma, the mixed H--/H∞ performance and the D-stability requirement are guaranteed by solving a convex optimization problem. An iterative algorithm for designing the desired FD filter is proposed by evaluating the threshold on the generated residual function. A simulation result is exploited to illustrate the effectiveness of the proposed design technique.This work was supported in part by the Deanship of Scientific Research (DSR) at King Abdulaziz University in Saudi Arabia under Grant 16-135- 35-HiCi, the National Natural Science Foundation of China under Grants 61134009 and 61203139, the Royal Society of the U.K., and the Alexander von Humboldt Foundation of Germany

L-Visibility Drawings of IC-planar Graphs

An IC-plane graph is a topological graph where every edge is crossed at most once and no two crossed edges share a vertex. We show that every IC-plane graph has a visibility drawing where every vertex is an L-shape, and every edge is either a horizontal or vertical segment. As a byproduct of our drawing technique, we prove that an IC-plane graph has a RAC drawing in quadratic area with at most two bends per edge

Dental caries and erosion status of 12-year-old Hong Kong children

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Grid Voltage Synchronization for Unbalanced Voltages Using the Energy Operator

This paper presents a novel synchronization technique which can identify the grid voltage frequency and phase angle under unbalanced grid voltage conditions. The method combines the features of two different energy operator schemes: the basic one for estimating the frequency of the grid voltages and the cross-energy operator for phase tracking. Using a moving data window of five samples the algorithm can track the fundamental frequency and phase angle quickly and accurately. The paper discusses the fundamental principles of the method, highlights its features and filter requirements in implementation. An experimental implementation of this method is presented which validates its performance for practical operation. The ability of the proposed method to enable a STATCOM riding-through unbalanced grid voltage condition is verified by the results from a power network simulation study

Resonance Raman scattering in bulk 2H-MX2 (M=Mo, W; X=S, Se) and monolayer MoS2

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Inactivation of hypoxia inducible factor (HIF) 1 alpha induces obesity-associated metabolic disorders through brown adipose tissue dysfunction

published_or_final_versionThe 14th Medical Research Conference, Hong Kong, 10 January 2009. In Hong Kong Medical Journal, 2009, v. 15, suppl. 1, p. 40, article no. 6

Dynamical Axion Field in Topological Magnetic Insulators

Axions are very light, very weakly interacting particles postulated more than 30 years ago in the context of the Standard Model of particle physics. Their existence could explain the missing dark matter of the universe. However, despite intensive searches, they have yet to be detected. In this work, we show that magnetic fluctuations of topological insulators couple to the electromagnetic fields exactly like the axions, and propose several experiments to detect this dynamical axion field. In particular, we show that the axion coupling enables a nonlinear modulation of the electromagnetic field, leading to attenuated total reflection. We propose a novel optical modulators device based on this principle.Comment: 5 pages, 3 figure

Interactions in vivo between the Vif protein of HIV-1 and the precursor (Pr55GAG) of the virion nucleocapsid proteins

The abnormality of viral core structure seen in vif-defective HIV-1 grown in PBMCs has suggested a role for Vif in viral morphogenesis. Using an in vivo mammalian two-hybrid assay, the interaction between Vif and the precursor (Pr55GAG) of the virion nucleocapsid proteins has been analysed. This revealed the amino-terminal (aa 1–22) and central (aa 70–100) regions of Vif to be essential for its interaction with Pr55GAG, but deletion of the carboxy-terminal (aa 158–192) region of the protein had only a minor effect on its interaction. Initial deletion studies carried out on Pr55GAG showed that a 35-amino-acid region of the protein bridging the MA(p17)–CA(p24) junction was essential for its ability to interact with Vif. Site-directed mutagenesis of a conserved tryptophan (Trp21) near the amino terminus of Vif showed it to be important for the interaction with Pr55GAG. By contrast, mutagenesis of the highly conserved YLAL residues forming part of the BC-box motif, shown to be important in Vif promoting degradation of APOBEC3G/3F, had little or no effect on the Vif–Pr55GAG interaction

T-Bet and Eomes Regulate the Balance between the Effector/Central Memory T Cells versus Memory Stem Like T Cells

Memory T cells are composed of effector, central, and memory stem cells. Previous studies have implicated that both T-bet and Eomes are involved in the generation of effector and central memory CD8 T cells. The exact role of these transcription factors in shaping the memory T cell pool is not well understood, particularly with memory stem T cells. Here, we demonstrate that both T-bet or Eomes are required for elimination of established tumors by adoptively transferred CD8 T cells. We also examined the role of T-bet and Eomes in the generation of tumor-specific memory T cell subsets upon adoptive transfer. We showed that combined T-bet and Eomes deficiency resulted in a severe reduction in the number of effector/central memory T cells but an increase in the percentage of CD62LhighCD44low Sca-1+ T cells which were similar to the phenotype of memory stem T cells. Despite preserving large numbers of phenotypic memory stem T cells, the lack of both of T-bet and Eomes resulted in a profound defect in antitumor memory responses, suggesting T-bet and Eomes are crucial for the antitumor function of these memory T cells. Our study establishes that T-bet and Eomes cooperate to promote the phenotype of effector/central memory CD8 T cell versus that of memory stem like T cells. © 2013 Li et al