Epidemiological characteristics of non-polio enteroviruses in respiratory infections: An Italian multicentre retrospective study, 2022-2023.

• Laboratory-based activities are essential for monitoring non-polio enteroviruses (NPEVs). • Despite their significant impact, there is no international surveillance for NPEVs. • This study investigated 35,532 respiratory samples for NPEV-RNA over one year. • 78.7% of NPEV-positive cases were in children under 15 years of age. • Molecular testing and sequencing revealed an EV-D68 and an echovirus-11 outbreak