6,832 research outputs found
Security Issues Threats in IoT Infrastructure
IoT (Internet of Things) expands the future Internet, and has drawn much attention. As more and more gadgets (i.e. Things) connected to the Internet, the huge amount of data exchanged has reached an unprecedented level.IoT today has a wide scope and researches say that IoT will definitely be a huge reason in the change of human lifestyle. But irrespective of the scope of IoT, we cannot be sure enough to implement it due to the security concerns. There is a genuine need to secure IoT, which has therefore resulted in a need to comprehensively understand the threats and attacks on IoT infrastructure. This paper discusses about the flaws in the security structure of IoT, it is a study about the various layers of IoT and how differentattacks are possible in those layers
Evaluation of Microparticulate Ovarian Cancer Vaccine via Transdermal Route of Delivery
Ovarian cancer is the fifth most commonly occurring malignancy in women, with the highest mortality rate among all the gynecological tumors. Microparticulate vaccine can serve as an immunotherapeutic approach with a promising antigenic delivery system without a need for conventional adjuvants. In this study, a microparticulate vaccine using whole cell lysate of a murine ovarian cancer cell line, ID8 was prepared by spray drying. Further, the effect of interleukins (ILs) such as IL-2 and IL-12 was evaluated in a separate study group by administering them with vaccine particles to enhance the immune response. The vaccine microparticles were administered to C57BL/6 female mice via transdermal alone and in combination with the oral route. The transdermal vaccine was delivered using a metallic microneedle device, AdminPen™. Orally administered microparticles also included an M-cell targeting ligand, Aleuria aurantia lectin, to enhance the targeted uptake from microfold cells (M-cells) in Peyer\u27s patches of small intestine. In case of combination of routes, mice were given 5 transdermal doses and 5 oral doses administered alternatively, beginning with transdermal dose. At the end of vaccination, mice were challenged with live tumor cells. Vaccine alone resulted in around 1.5 times tumor suppression in case of transdermal and combination of routes at the end of 15th week when compared to controls. Inclusion of interleukins resulted in 3 times tumor suppression when administered with transdermal vaccine and around 9 times tumor suppression for the combination route of delivery in comparison to controls. These results were further potentiated by serum IgG, IgG1 and IgG2a titers. Moreover, CD8+ T-cell, CD4+ T-cell and NK (natural killer) cell populations in splenocytes were elevated in case of vaccinated mice. Thus, vaccine microparticles could trigger humoral as well as cellular immune response when administered transdermally and via combination of route of delivery. However overall, vaccine administered with interleukins, via combination of route, was found to be the most efficacious to suppress the tumor growth and lead to a protective immune response
Validating delta-filters for resonant bar detectors of improved bandwidth foreseeing the future coincidence with interferometers
The classical delta filters used in the current resonant bar experiments for
detecting GW bursts are viable when the bandwidth of resonant bars is few Hz.
In that case, the incoming GW burst is likely to be viewed as an impulsive
signal in a very narrow frequency window. After making improvements in the
read-out with new transducers and high sensitivity dc-SQUID, the
Explorer-Nautilus have improved the bandwidth ( Hz) at the sensitivity
level of . Thus, it is necessary to reassess this
assumption of delta-like signals while building filters in the resonant bars as
the filtered output crucially depends on the shape of the waveform. This is
presented with an example of GW signals -- stellar quasi-normal modes, by
estimating the loss in SNR and the error in the timing, when the GW signal is
filtered with the delta filter as compared to the optimal filter.Comment: 7 pages, presented in Amaldi6, accepted for publication in Journal of
Physics: Conference Serie
Impact of Environmental Degradation on Human Health
Degradation of environment is one of the most serious challenges before the mankind in today's world. Mankind has been facing a wide range of problem arising out of the degradation of environment. Not only the areas under human inhabitation, but the areas of the planet without human population have also been suffering from these problems. As the population increase day by day, the amenities are not improved simultaneously. With the advancement of science and technologies the needs of human beings has been changing rapidly. As a result different types of environmental problems have been rising. Environmental degradation is a wide- reaching problem and it is likely to influence the health of human population is great. It may be defined the deterioration of the environment through depletion of resources such as air, water, and soil. The destruction of ecosystem and extinction of wildlife. Environmental degradation has occurred due to the recent activities in the field of socio-economic, institute and technology. Poverty still remains a problem as the root of several environmental problems to create awareness among the people about the ill effect of environmental pollution. In the whole research it is clear that all factors of environmental degradation may be reduced through- Framing the new laws on environmental degradation, Environment friend policy, Controlling all the ways and means of noise, air, soil and water pollution, Through growing more and more trees and by adapting the proper sanitation policy. 
Real Space Visualization of Thermomagnetic Irreversibility within Supercooling and Superheating Spinodals in using Scanning Hall Probe Microscopy
Phase coexistence across disorder-broadened and magnetic-field-induced first
order antiferromagnetic to ferrimagnetic transition in polycrystalline
has been studied mesoscopically by Scanning Hall Probe
Microscope at 120K and up to 5 Tesla magnetic fields. We have observed
hysteresis with varying magnetic field and the evolution of coexisting
antiferromagnetic and ferrimagnetic state on mesoscopic length scale. These
studies show that the magnetic state of the system at low field depends on the
path followed to reach 120 K. The low field magnetic states are mesoscopically
different for virgin and second field increasing cycle when 120 K is reached by
warming from 5K, but are the same within measurement accuracy when the
measuring temperature of 120K is reached from 300K by cooling
Implementation of Deduplication on Encrypted Big-data using Signcryption for cloud storage applications
As Big Data Cloud storage servers are getting widespread the shortage of disc space within the cloud becomes a major concern. The elimination of duplicate or redundant data, particularly in computer data is named deduplication. Data deduplication is a method to regulate the explosive growth of information within the cloud storage, most of the storage providers are finding more secure and efficient methods for their sensitive method.
Recently, a noteworthy technique referred to as signcryption has been proposed, in which both the properties of signature (ownership) and encryption are simultaneously implemented with better performance
According to deduplication, we introduce a method that can eliminate redundant encrypted data owned by different users. Furthermore, we generate a tag which will be the key component of big data management. We propose a technique called digital signature for ownership verification. Convergent encryption also called for a content hash key cryptosystem. Convergent encryption is an encryption approach that supports deduplication. With this encryption technique, the encryption key is generated out of a hash of plain text. Therefore applying this technique, identical plaintexts would turn out the same ciphertext
Implementation of low-loss superinductances for quantum circuits
The simultaneous suppression of charge fluctuations and offsets is crucial
for preserving quantum coherence in devices exploiting large quantum
fluctuations of the superconducting phase. This requires an environment with
both extremely low DC and high RF impedance. Such an environment is provided by
a superinductance, defined as a zero DC resistance inductance whose impedance
exceeds the resistance quantum at
frequencies of interest (1 - 10 GHz). In addition, the superinductance must
have as little dissipation as possible, and possess a self-resonant frequency
well above frequencies of interest. The kinetic inductance of an array of
Josephson junctions is an ideal candidate to implement the superinductance
provided its phase slip rate is sufficiently low. We successfully implemented
such an array using large Josephson junctions (), and measured
internal losses less than 20 ppm, self-resonant frequencies greater than 10
GHz, and phase slip rates less than 1 mHz
Heisenberg-limited qubit readout with two-mode squeezed light
We show how to use two-mode squeezed light to exponentially enhance
cavity-based dispersive qubit measurement. Our scheme enables true
Heisenberg-limited scaling of the measurement, and crucially, is not restricted
to small dispersive couplings or unrealistically long measurement times. It
involves coupling a qubit dispersively to two cavities, and making use of a
symmetry in the dynamics of joint cavity quadratures (a so-called
quantum-mechanics-free subsystem). We discuss the basic scaling of the scheme
and its robustness against imperfections, as well as a realistic implementation
in circuit quantum electrodynamics.Comment: 5 pages, 4 figures, Supplemental Materia
Minimal Models for Nonreciprocal Amplification Using Biharmonic Drives
We present a generic system of three bosonic modes coupled parametrically with a time-varying coupling modulated by a combination of two pump harmonics, and we show how this system provides the minimal platform for realizing nonreciprocal couplings that can lead to gainless photon circulation, and phase-preserving or phase-sensitive directional amplification. Explicit frequency-dependent calculations within this minimal paradigm highlight the separation of amplification and directionality bandwidths, a feature generic to such schemes. We also study the influence of counterrotating interactions that can adversely affect directionality and the associated bandwidth; we find that these effects can be mitigated by suitably designing the properties of the auxiliary mode that plays the role of an engineered reservoir to the amplification mode space.University of Massachusetts at Lowel
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