37 research outputs found

    Da Criminologia à Biopolítica: O Campo E A Vida Nua Como Paradigmas Do Sistema Prisional

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    Trata-se de pesquisa acerca do conceito de biopolítica, em especial de seu desenvolvimento nos trabalhos realizados por Michel Foucault e continuados por Giorgio Agamben. Almeja-se, a partir do diagnóstico realizado por Agamben, dos diálogos entre Foucault e Deleuze e das recentes pesquisas no sistema penitenciário de Minas Gerais, pensar a criminologia direcionada à execução penal não mais nos moldes da normalização apresentados por Foucault, nem na perspectiva marxista dos objetivos econômicos ligados à prática do encarceramento, mas sim com base nos conceitos de exceção no direito e de vida nua identificados por Agamben na contemporaneidade910012

    NuSTAR Detection of the Blazar B2 1023+25 at Redshift 5.3

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    B2 1023+25 is an extremely radio-loud quasar at z = 5.3 that was first identified as a likely high-redshift blazar candidate in the SDSS+FIRST quasar catalog. Here, we use the Nuclear Spectroscopic Telescope Array (NuSTAR) to investigate its non-thermal jet emission, whose high-energy component we detected in the hard X-ray energy band. The X-ray flux is ~ 5.5 x 10^(-14)erg cm^(-2) s^(-1) (5-10 keV) and the photon spectral index is Γ_X ≃ 1.3-1.6. Modeling the full spectral energy distribution, we find that the jet is oriented close to the line of sight, with a viewing angle of ~3°, and has significant Doppler boosting, with a large bulk Lorentz factor ~13, which confirms the identification of B2 1023+25 as a blazar. B2 1023+25 is the first object at redshift larger than 5 detected by NuSTAR, demonstrating the ability of NuSTAR to investigate the early X-ray universe and to study extremely active supermassive black holes located at very high redshift

    Visceral Obesity and Its Shared Role in Cancer and Cardiovascular Disease: A Scoping Review of the Pathophysiology and Pharmacological Treatments

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    The association between obesity, cancer and cardiovascular disease (CVD) has been demonstrated in animal and epidemiological studies. However, the specific role of visceral obesity on cancer and CVD remains unclear. Visceral adipose tissue (VAT) is a complex and metabolically active tissue, that can produce different adipokines and hormones, responsible for endocrine-metabolic comorbidities. This review explores the potential mechanisms related to VAT that may also be involved in cancer and CVD. In addition, we discuss the shared pharmacological treatments which may reduce the risk of both diseases. This review highlights that chronic inflammation, molecular aspects, metabolic syndrome, secretion of hormones and adiponectin associated to VAT may have synergistic effects and should be further studied in relation to cancer and CVD. Reductions in abdominal and visceral adiposity improve insulin sensitivity, lipid profile and cytokines, which consequently reduce the risk of CVD and some cancers. Several medications have shown to reduce visceral and/or subcutaneous fat. Further research is needed to investigate the pathophysiological mechanisms by which visceral obesity may cause both cancer and CVD. The role of visceral fat in cancer and CVD is an important area to advance. Public health policies to increase public awareness about VAT’s role and ways to manage or prevent it are needed
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