Methanol and isopropanol embryo dosage response curves for wild-type and ethanol-sensitive zebrafish

It is well established that ethanol has an array of negative effects on developing embryos, from craniofacial abnormalities to cognitive deficits and behavioral disorders. Fetal Alcohol Spectrum Disorders (FASD) describes this phenotypic spectrum caused by embryonic ethanol exposure. However, the effects of other small alcohols, such as methanol and isopropanol, have on development are poorly understood. Multiple factors can contribute to the teratogenicity of small alcohols, including timing, dosage and genetic background. Zebrafish (Danio rerio) has been shown to be a powerful model in the study ethanol teratogenesis and can serve as a model to study methanol and isopropanol teratogenicity. Here we provide evidence of the dose response to methanol and isopropanol in a wild type and an ethanol- sensitive mutant zebrafish line. We determine the lethal concentrations of methanol and isopropanol on wild type and ethanol-sensitive mutants. We also show effective dose that leads to malformations of the craniofacial skeleton, including defects to the lower jaw and palate. Our data suggest that ethanol-sensitivity may predict sensitivity to other small alcohols. Overall, our results begin to characterize the effects of methanol and isopropanol on developing embryos.Molecular Bioscience

Community Use of the Sacred Heart School

In October 2005, the Edmonton Social Planning Council (ESPC) released a report entitled The Sacred Heart Collective: An Effective Use of a Closed School? which evaluated the unique initiative implemented by the Sacred Heart Collective (the Collective), a group of seven non-profits located in the former Sacred Heart School. In agreement with Edmonton Catholic Schools, the Collective sought to provide free access to meeting and recreational space located in the school to other non-profits and local community groups.The following is a follow-up to the October 2005 report, and details usage of the Sacred Heart facilities for a six month period, from August 2005 to end of January 2006

Acts of Heritage, Acts of Value: Memorializing at the Chattri Indian Memorial, UK

The Chattri Indian Memorial is a public site that hosts and embodies heritage in complex ways. Standing on the edge of Brighton, UK in a once-remote part of the Sussex Downs, the Memorial was built in 1921 to honour Indian soldiers who fought on the Western Front during the First World War. As both a sacred place and a space of socio-cultural heritagization processes, the monument is an enduring testament of past values of war heroism, but also more ephemeral practices of ritual. The article documents the heritage-making at work within memorialization at the Chattri as a case study, examining how differing ‘valuations’ of a memorial site can be enacted through time, between material form and immaterial practices, and across cultures. The article theorizes participants’ current affective practices as conscious ‘past presencing’ (Macdonald, 2013), and analyses how their conscious acts of heritage-making affectively enacted values of morality, community and belonging

Exploring different 'perspectives' in secondary geography: Professional development options

Significant changes have occurred in the worlds of geography since 1973, and a substantial literature has emerged about these changes and their effects on the 'divide' between secondary and tertiary geographers. We suggest that while the divide has not had much effect on the content taught in secondary geography in New Zealand and Britain, exposure to a range of perspectives on this content is a neglected area of professional development. Post-Fordism and deep ecology are described as perspectives that are not widely used in delivering secondary geography content. We argue firstly that effective use of different perspectives needs to be based on professional, personal and social change, and secondly that the Internet is a powerful tool in the engineering of such change

The suit maketh the man: Masculinity and social class in Kingsman: The Secret Service (Vaughn, 2014)

This article outlines the ways in which suits are synonymous with masculinity examining the, sometimes paradoxical, nature of suits worn by men of all social classes, and for different reasons. For example, hegemonic men wear suits in a bid to convey power, arguably, by rendering the wearers uniform in appearance so that the focus is on what hegemonic men might say and do, rather than how they might look. Moreover, the uniformity of suits is a means by which men of a lower social class demonstrate aspiration to a higher social class and might affect hegemonic power through wearing them. While much has been written about masculinity and suits, with many authors agreeing that the bespoke suit is at the pinnacle of the hierarchy of men’s clothing, yet there is a little attention paid to the way in which the bespoke suit is represented in media or popular culture. This article examines the role of clothing of the main characters in the film Kingsman: The Secret Service (2014) with a particular focus on the contribution that the bespoke suit makes to the masculinity of the bodies of the individuals within the film. Principally, the bespoke suit elevates the body of the wearer from quotidian to tailored, the fitting of which allows for better representation of a man’s body

Social Media Strategic Plan For Under Armour

This thesis is a study of the effects of social media on an organization’s integrated marketing communications strategy in general and provides a proposal of how the sports apparel company Under Armour could use social media to enhance its promotional strategies. It is a discussion of the implications that social media has on consumer behavior with focus on how social media has changed the way today’s consumers interact with brands. This thesis provides an analysis of the growing importance of social media being implemented within a business. Benefits discussed include the appeal of social media over traditional media, increased customer satisfaction, increased loyalty, and brand awareness. A list of essential social media networking sites is discussed under the different platforms of networking, promoting and sharing, highlighting their importance to a business. Under Armour’s current social media presence is discussed and how social media has become a new component of the Integrated Marketing Communications (IMC) mix. An illustration of how Homeland/Embassy strategy uses social media is provided as an example of how Under Armour could use social media in its IMC mix