Large distance expansion of Mutual Information for disjoint disks in a free scalar theory

We compute the next-to-leading order term in the long-distance expansion of the mutual information for free scalars in three space-time dimensions. The geometry considered is two disjoint disks separated by a distance $r$ between their centers. No evidence for non-analyticity in the R\'enyi parameter $n$ for the continuation $n \rightarrow 1$ in the next-to-leading order term is found.Comment: 15 pages, This version contains few extra references, some technical material has been move to appendices, and other minor modifications to match with the version accepted for publicatio

Characterization of the slow wind in the outer corona

The study concerns the streamer belt observed at high spectral resolution during the minimum of solar cycle 22 with the Ultraviolet Coronagraph Spectrometer (UVCS) onboard SOHO. On the basis of a spectroscopic analysis of the O VI doublet, the solar wind plasma parameters are inferred in the extended corona. The analysis accounts for the coronal magnetic topology, extrapolated through a 3D magneto-hydrodynamic model, in order to define the streamer boundary and to analyse the edges of coronal holes. The results of the analysis allow an accurate identification of the source regions of the slow coronal wind that are confirmed to be along the streamer boundary in the open magnetic field region.Comment: 5 figures, work presented with an oral presentation on 37th COSPAR Scientific Assembly, 13 - 20 July 2008, Montreal, Canad

A Simple Microbiome in the European Common Cuttlefish, Sepia officinalis.

The European common cuttlefish, Sepia officinalis, is used extensively in biological and biomedical research, yet its microbiome remains poorly characterized. We analyzed the microbiota of the digestive tract, gills, and skin in mariculture-raised S. officinalis using a combination of 16S rRNA amplicon sequencing, quantitative PCR (qPCR), and fluorescence spectral imaging. Sequencing revealed a highly simplified microbiota consisting largely of two single bacterial amplicon sequence variants (ASVs) of Vibrionaceae and Piscirickettsiaceae The esophagus was dominated by a single ASV of the genus Vibrio Imaging revealed bacteria in the family Vibrionaceae distributed in a discrete layer that lines the esophagus. This Vibrio was also the primary ASV found in the microbiota of the stomach, cecum, and intestine, but occurred at lower abundance, as determined by qPCR, and was found only scattered in the lumen rather than in a discrete layer via imaging analysis. Treatment of animals with the commonly used antibiotic enrofloxacin led to a nearly 80% reduction of the dominant Vibrio ASV in the esophagus but did not significantly alter the relative abundance of bacteria overall between treated versus control animals. Data from the gills were dominated by a single ASV in the family Piscirickettsiaceae, which imaging visualized as small clusters of cells. We conclude that bacteria belonging to the Gammaproteobacteria are the major symbionts of the cuttlefish Sepia officinalis cultured from eggs in captivity and that the esophagus and gills are major colonization sites.IMPORTANCE Microbes can play critical roles in the physiology of their animal hosts, as evidenced in cephalopods by the role of Vibrio (Aliivibrio) fischeri in the light organ of the bobtail squid and the role of Alpha- and Gammaproteobacteria in the reproductive system and egg defense in a variety of cephalopods. We sampled the cuttlefish microbiome throughout the digestive tract, gills, and skin and found dense colonization of an unexpected site, the esophagus, by a microbe of the genus Vibrio, as well as colonization of gills by Piscirickettsiaceae This finding expands the range of organisms and body sites known to be associated with Vibrio and is of potential significance for understanding host-symbiont associations, as well as for understanding and maintaining the health of cephalopods in mariculture

Morphology, dynamics and plasma parameters of plumes and inter-plume regions in solar coronal holes

Coronal plumes, which extend from solar coronal holes (CH) into the high corona and - possibly - into the solar wind (SW), can now continuously be studied with modern telescopes and spectrometers on spacecraft, in addition to investigations from the ground, in particular, during total eclipses. Despite the large amount of data available on these prominent features and related phenomena, many questions remained unanswered as to their generation and relative contributions to the high-speed streams emanating from CHs. An understanding of the processes of plume formation and evolution requires a better knowledge of the physical conditions at the base of CHs, in plumes and in the surrounding inter-plume regions (IPR). More specifically, information is needed on the magnetic field configuration, the electron densities and temperatures, effective ion temperatures, non-thermal motions, plume cross-sections relative to the size of a CH, the plasma bulk speeds, as well as any plume signatures in the SW. In spring 2007, the authors proposed a study on "Structure and dynamics of coronal plumes and inter-plume regions in solar coronal holes" to the International Space Science Institute (ISSI) in Bern to clarify some of these aspects by considering relevant observations and the extensive literature. This review summarizes the results and conclusions of the study. Stereoscopic observations allowed us to include three-dimensional reconstructions of plumes. Multi-instrument investigations carried out during several campaigns led to progress in some areas, such as plasma densities, temperatures, plume structure and the relation to other solar phenomena, but not all questions could be answered concerning the details of plume generation process(es) and interaction with the SW.Comment: To appear on: The Astronomy and Astrophysics Review. 72 pages, 30 figure

Spectroscopic signature of Alfv\'en waves damping in a polar coronal hole up to 0.4 solar radii

Between February 24-25, 2009, the EIS spectrometer onboard the Hinode spacecraft performed special "sit & stare" observations above the South polar coronal hole continuously over more than 22 hours. Spectra were acquired with the 1" slit placed off-limb covering altitudes up to 0.48 R$_\odot$ ($3.34\times 10^2$ Mm) above the Sun surface, in order to study with EIS the non-thermal spectral line broadenings. Spectral lines such as Fe {\sc xii} $\lambda$186.88, Fe {\sc xii} $\lambda$193.51, Fe {\sc xii} $\lambda$195.12 and Fe {\sc xiii} $\lambda$202.04 are observed with good statistics up to high altitudes and they have been analyzed in this study. Results show that the FWHM of Fe {\sc xii} $\lambda$195.12 line increases up to $\simeq 0.14$ R$_\odot$, then decreases higher up. EIS stray light has been estimated and removed. Derived electron density and non-thermal velocity profiles have been used to estimate the total energy flux transported by Alfv\'en waves off-limb in polar coronal hole up to $\simeq 0.4$ R$_\odot$. The computed Alfv\'en wave energy flux density $f_w$ progressively decays with altitude from $f_w \simeq 1.2 \cdot 10^6$ erg cm$^{-2}$ s$^{-1}$ at 0.03 R$_\odot$ down to $f_w \simeq 8.5 \cdot 10^3$ erg cm$^{-2}$ s$^{-1}$ at 0.4 R$_\odot$, with an average energy decay rate $\Delta f_w / \Delta h \simeq -4.5 \cdot 10^{-5}$ erg cm$^{-3}$ s$^{-1}$. Hence, this result suggests energy deposition by Alfv\'en waves in a polar coronal hole, thus providing a significant source for coronal heating.Comment: Physical units of the Alfv\'en wave Energy Decay Rate $\Delta f_w / \Delta h$ revised with respect to the published version. Scientific results and conclusions unchange

Response to foot and mouth disease (FMD) vaccination among local Malaysian cattle of various vaccination backgrounds from endemic and non-endemic FMD areas

A longitudinal study assessed the response to foot and mouth disease virus (FMDV) vaccination on sequential sera of local Malaysian Kedah-Kelantan cattle in two states of Peninsular Malaysia; Perlis, a foot and mouth (FMD) disease non-endemic state, and Kelantan, an endemic state for FMD. These cattle were from various vaccination backgrounds and some with unknown vaccination status. For the cattle in both states, the antibody against FMDV type O effectively increased to a strong protective level in the first week following vaccination, regardless of the vaccination background of the animals. In the endemic state, where vaccination was performed more routinely than the non-endemic state, the response had better magnitude and duration. In the non-endemic state, the antibody response level was good but appeared to last for a shorter period of time before it significantly declined. For naïve cattle with no evidence of infection or vaccination, the response was rapid and reached a strong level immediately by the first week. However, the level was not sustained and significantly declined thereafter. All the cattle stayed healthy and clinically FMD- free throughout the study, even when there was a transient evidence of natural field infection detected among the cattle. A marked difference was observed in the patterns of antibody response between cattle in the FMD endemic and non-endemic areas. However, the level of antibodies generally rose to a strong protective level within the stipulated 7-14 days post-vaccination. The vaccine used was effective in eliciting immune response when naturally challenged by the local field FMD virus

Comparing extrapolations of the coronal magnetic field structure at 2.5 solar radii with multi-viewpoint coronagraphic observations

The magnetic field shapes the structure of the solar corona but we still know little about the interrelationships between the coronal magnetic field configurations and the resulting quasi-stationary structures observed in coronagraphic images (as streamers, plumes, coronal holes). One way to obtain information on the large-scale structure of the coronal magnetic field is to extrapolate it from photospheric data and compare the results with coronagraphic images. Our aim is to verify if this comparison can be a fast method to check systematically the reliability of the many methods available to reconstruct the coronal magnetic field. Coronal fields are usually extrapolated from photospheric measurements typically in a region close to the central meridian on the solar disk and then compared with coronagraphic images at the limbs, acquired at least 7 days before or after to account for solar rotation, implicitly assuming that no significant changes occurred in the corona during that period. In this work, we combine images from three coronagraphs (SOHO/LASCO-C2 and the two STEREO/SECCHI-COR1) observing the Sun from different viewing angles to build Carrington maps covering the entire corona to reduce the effect of temporal evolution to ~ 5 days. We then compare the position of the observed streamers in these Carrington maps with that of the neutral lines obtained from four different magnetic field extrapolations, to evaluate the performances of the latter in the solar corona. Our results show that the location of coronal streamers can provide important indications to discriminate between different magnetic field extrapolations.Comment: Accepted by A&A the 20th of May, 201

Pathological findings in the red fox (Vulpes vulpes), stone marten (Martes foina) and raccoon dog (Nyctereutes procyonoides), with special emphasis on infectious and zoonotic agents in Northern Germany

Anthropogenic landscape changes contributed to the reduction of availability of habitats to wild animals. Hence, the presence of wild terrestrial carnivores in urban and peri-urban sites has increased considerably over the years implying an increased risk of interspecies spillover of infectious diseases and the transmission of zoonoses. The present study provides a detailed characterisation of the health status of the red fox (Vulpes vulpes), stone marten (Martes foina) and raccoon dog (Nyctereutes procyonoides) in their natural rural and periurban habitats in Schleswig-Holstein, Germany between November 2013 and January 2016 with focus on zoonoses and infectious diseases that are potentially threatening to other wildlife or domestic animal species. 79 red foxes, 17 stone martens and 10 raccoon dogs were collected from traps or hunts. In order to detect morphological changes and potential infectious diseases, necropsy and pathohistological work-up was performed. Additionally, in selected animals immunohistochemistry (influenza A virus, parvovirus, feline leukemia virus, Borna disease virus, tick-borne encephalitis, canine adenovirus, Neospora caninum, Toxoplasma gondii and Listeria monocytogenes), next-generation sequencing, polymerase chain reaction (fox circovirus) and serum-neutralisation analysis (canine distemper virus) were performed. Furthermore, all animals were screened for fox rabies virus (immunofluorescence), canine distemper virus (immunohistochemistry) and Aujeszky's disease (virus cultivation). The most important findings included encephalitis (n = 16) and pneumonia (n =20). None of the investigations revealed a specific cause for the observed morphological alterations except for one animal with an elevated serum titer of 1:160 for canine distemper. Animals displayed macroscopically and/or histopathologically detectable infections with parasites, including Taenia sp., Toxocara sp. and Alaria alata. In summary, wildlife predators carry zoonotic parasitic disease and suffer from inflammatory diseases of yet unknown etiology, possibly bearing infectious potential for other animal species and humans. This study highlights the value of monitoring terrestrial wildlife following the "One Health" notion, to estimate the incidence and the possible spread of zoonotic pathogens and to avoid animal to animal spillover as well as transmission to humans

Quantitative trait loci conferring grain mineral nutrient concentrations in durum wheat 3 wild emmer wheat RIL population

Mineral nutrient malnutrition, and particularly deficiency in zinc and iron, afflicts over 3 billion people worldwide. Wild emmer wheat, Triticum turgidum ssp. dicoccoides, genepool harbors a rich allelic repertoire for mineral nutrients in the grain. The genetic and physiological basis of grain protein, micronutrients (zinc, iron, copper and manganese) and macronutrients (calcium, magnesium, potassium, phosphorus and sulfur) concentration was studied in tetraploid wheat population of 152 recombinant inbred lines (RILs), derived from a cross between durum wheat (cv. Langdon) and wild emmer (accession G18-16). Wide genetic variation was found among the RILs for all grain minerals, with considerable transgressive effect. A total of 82 QTLs were mapped for 10 minerals with LOD score range of 3.2–16.7. Most QTLs were in favor of the wild allele (50 QTLs). Fourteen pairs of QTLs for the same trait were mapped to seemingly homoeologous positions, reflecting synteny between the A and B genomes. Significant positive correlation was found between grain protein concentration (GPC), Zn, Fe and Cu, which was supported by significant overlap between the respective QTLs, suggesting common physiological and/or genetic factors controlling the concentrations of these mineral nutrients. Few genomic regions (chromosomes 2A, 5A, 6B and 7A) were found to harbor clusters of QTLs for GPC and other nutrients. These identified QTLs may facilitate the use of wild alleles for improving grain nutritional quality of elite wheat cultivars, especially in terms of protein, Zn and Fe

Audit of percutaneous nephrostomy in Rabat Urological Centre

Objectives: To audit and compare the different techniques for percutaneous nephrostomy (PCN) and assess the indication of each.Methods: Between March 2009 and November 2009, the records of 27 patients who underwent percutaneous nephrostomy were retrospectively reviewed. PCN procedures were performed under ultrasonography (US), computed tomography (CT) guidance or blindly according to the grade ofhydronephrosis. Results: US guided PCN were done for 15, CT guided PCN for 10 and blindly PCN for two patients. Overall success rate was 25 (92.6%). US guided PCN had success rate of 13 (86.6%), CT guided PCN eight (80%) while blindly PCN 2(100%). The overall complications were minimal.Conclusions: The success of PCN procedures depend mainly on the degree of hydronephrosis and selection of the appropriate image guidance.Key Words: Blind PCN, CT guided PCN, Ultrasound guided PCN,  Hydronephrosi