5,590 research outputs found

    3D gaze cursor: continuous calibration and end-point grasp control of robotic actuators

    No full text
    © 2016 IEEE.Eye movements are closely related to motor actions, and hence can be used to infer motor intentions. Additionally, eye movements are in some cases the only means of communication and interaction with the environment for paralysed and impaired patients with severe motor deficiencies. Despite this, eye-tracking technology still has a very limited use as a human-robot control interface and its applicability is highly restricted to 2D simple tasks that operate on screen based interfaces and do not suffice for natural physical interaction with the environment. We propose that decoding the gaze position in 3D space rather than in 2D results into a much richer spatial cursor signal that allows users to perform everyday tasks such as grasping and moving objects via gaze-based robotic teleoperation. Eye tracking in 3D calibration is usually slow - we demonstrate here that by using a full 3D trajectory for system calibration generated by a robotic arm rather than a simple grid of discrete points, gaze calibration in the 3 dimensions can be successfully achieved in short time and with high accuracy. We perform the non-linear regression from eye-image to 3D-end point using Gaussian Process regressors, which allows us to handle uncertainty in end-point estimates gracefully. Our telerobotic system uses a multi-joint robot arm with a gripper and is integrated with our in-house GT3D binocular eye tracker. This prototype system has been evaluated and assessed in a test environment with 7 users, yielding gaze-estimation errors of less than 1cm in the horizontal, vertical and depth dimensions, and less than 2cm in the overall 3D Euclidean space. Users reported intuitive, low-cognitive load, control of the system right from their first trial and were straightaway able to simply look at an object and command through a wink to grasp this object with the robot gripper

    The Road to Quantum Computational Supremacy

    Full text link
    We present an idiosyncratic view of the race for quantum computational supremacy. Google's approach and IBM challenge are examined. An unexpected side-effect of the race is the significant progress in designing fast classical algorithms. Quantum supremacy, if achieved, won't make classical computing obsolete.Comment: 15 pages, 1 figur

    Quantum advantage by relational queries about physically realizable equivalence classes

    Full text link
    Relational quantum queries are sometimes capable to effectively decide between collections of mutually exclusive elementary cases without completely resolving and determining those individual instances. Thereby the set of mutually exclusive elementary cases is effectively partitioned into equivalence classes pertinent to the respective query. In the second part of the paper, we review recent progress in theoretical certifications (relative to the assumptions made) of quantum value indeterminacy as a means to build quantum oracles for randomness.Comment: 8 Pages, one figure, invited contribution to TopHPC2019, Tehran, Iran, April 22-25, 201

    Cooling a nanomechanical resonator with quantum back-action

    Get PDF
    Quantum mechanics demands that the act of measurement must affect the measured object. When a linear amplifier is used to continuously monitor the position of an object, the Heisenberg uncertainty relationship requires that the object be driven by force impulses, called back-action. Here we measure the back-action of a superconducting single-electron transistor (SSET) on a radiofrequency nanomechanical resonator. The conductance of the SSET, which is capacitively coupled to the resonator, provides a sensitive probe of the latter's position;back-action effects manifest themselves as an effective thermal bath, the properties of which depend sensitively on SSET bias conditions. Surprisingly, when the SSET is biased near a transport resonance, we observe cooling of the nanomechanical mode from 550mK to 300mK-- an effect that is analogous to laser cooling in atomic physics. Our measurements have implications for nanomechanical readout of quantum information devices and the limits of ultrasensitive force microscopy (such as single-nuclear-spin magnetic resonance force microscopy). Furthermore, we anticipate the use of these backaction effects to prepare ultracold and quantum states of mechanical structures, which would not be accessible with existing technology.Comment: 28 pages, 7 figures; accepted for publication in Natur

    Quantum nondemolition measurement of mechanical motion quanta

    Get PDF
    The fields of opto- and electromechanics have facilitated numerous advances in the areas of precision measurement and sensing, ultimately driving the studies of mechanical systems into the quantum regime. To date, however, the quantization of the mechanical motion and the associated quantum jumps between phonon states remains elusive. For optomechanical systems, the coupling to the environment was shown to preclude the detection of the mechanical mode occupation, unless strong single photon optomechanical coupling is achieved. Here, we propose and analyse an electromechanical setup, which allows to overcome this limitation and resolve the energy levels of a mechanical oscillator. We find that the heating of the membrane, caused by the interaction with the environment and unwanted couplings, can be suppressed for carefully designed electromechanical systems. The results suggest that phonon number measurement is within reach for modern electromechanical setups.Comment: 8 pages, 5 figures plus 24 pages, 11 figures supplemental materia

    Melarsoprol cyclodextrin inclusion complexes as promising oral candidates for the treatment of human African trypanosomiasis

    Get PDF
    Human African trypanosomiasis (HAT), or sleeping sickness, results from infection with the protozoan parasites <i>Trypanosoma brucei</i> (<i>T.b.</i>) <i>gambiense</i> or <i>T.b.rhodesiense</i> and is invariably fatal if untreated. There are 60 million people at risk from the disease throughout sub-Saharan Africa. The infection progresses from the haemolymphatic stage where parasites invade the blood, lymphatics and peripheral organs, to the late encephalitic stage where they enter the central nervous system (CNS) to cause serious neurological disease. The trivalent arsenical drug melarsoprol (Arsobal) is the only currently available treatment for CNS-stage <i>T.b.rhodesiense</i> infection. However, it must be administered intravenously due to the presence of propylene glycol solvent and is associated with numerous adverse reactions. A severe post-treatment reactive encephalopathy occurs in about 10% of treated patients, half of whom die. Thus melarsoprol kills 5% of all patients receiving it. Cyclodextrins have been used to improve the solubility and reduce the toxicity of a wide variety of drugs. We therefore investigated two melarsoprol cyclodextrin inclusion complexes; melarsoprol hydroxypropyl-͎-cyclodextrin and melarsoprol randomly-methylated-β-cyclodextrin. We found that these compounds retain trypanocidal properties <i>in vitro</i> and cure CNS-stage murine infections when delivered orally, once per day for 7-days, at a dosage of 0.05 mmol/kg. No overt signs of toxicity were detected. Parasite load within the brain was rapidly reduced following treatment onset and magnetic resonance imaging showed restoration of normal blood-brain barrier integrity on completion of chemotherapy. These findings strongly suggest that complexed melarsoprol could be employed as an oral treatment for CNS-stage HAT, delivering considerable improvements over current parenteral chemotherapy
    corecore