744 research outputs found
La investigaci?n formativa en el programa de licenciatura en educaci?n b?sica con ?nfasis en lengua castellana IDEAD
105 p. Recurso Electr?nicoLa investigaci?n formativa es la estrategia pedag?gica utilizada en el programa de Licenciatura en Educaci?n B?sica con ?nfasis en Lengua Castellana del IDEAD para fortalecer la cultura investigativa en sus estudiantes. El presente trabajo monogr?fico denominado ?La investigaci?n formativa en el programa de Licenciatura en Educaci?n B?sica con ?nfasis en Lengua Castellana del IDEAD? pretende conocer si se est?n cumpliendo los prop?sitos de la investigaci?n formativa, encontrar sus falencias y fortalezas en este programa en el CREAD Ibagu? a partir del an?lisis y la interpretaci?n de encuestas aplicadas a todos los estudiantes matriculados para el semestre B de 2015.
En el desarrollo de la investigaci?n se presentan unos antecedentes de la investigaci?n formativa desde sus inicios en el programa Licenciatura en Educaci?n B?sica con ?nfasis en Lengua Castellana y de la revisi?n de los Acuerdos y Resoluciones facilitados por la secretaria del programa.The formative research is a pedagogical strategy implemented in the program of Licenciatura en educaci?n b?scia con enfasis en Lengua castellana of IDEAD to strengthen the investigative culture in the students belonging to this academic program. This monographic research is named ?La investigaci?n formativa en el programa de Licenciatura en educaci?n b?sica con enf?sis en Lengua Castellana del IDEAD? aims to know if the formative research purposes are being fulfilled, also, to find if its weaknesses and strengths into the program in the CREAD Ibagu? from the analysis and interpretation of surveys applied to whole students enrolled in the semester B of 2015.
In the research development are presented some background regarding to formative research from the beginning of the program which were built through interviews done forteachers who has been the head of the program "Licenciatura en educaci?n b?sica con ?nfasis en Lengua Castellana del IDEAD" and the agreements review and resolutions given by the office of the program.
Keywords: Formative research, research culture, pedagogical strategies
Lattice Model for water-solute mixtures
A lattice model for the study of mixtures of associating liquids is proposed.
Solvent and solute are modeled by adapting the associating lattice gas (ALG)
model. The nature of interaction solute/solvent is controlled by tuning the
energy interactions between the patches of ALG model. We have studied three set
of parameters, resulting on, hydrophilic, inert and hydrophobic interactions.
Extensive Monte Carlo simulations were carried out and the behavior of pure
components and the excess properties of the mixtures have been studied. The
pure components: water (solvent) and solute, have quite similar phase diagrams,
presenting: gas, low density liquid, and high density liquid phases. In the
case of solute, the regions of coexistence are substantially reduced when
compared with both the water and the standard ALG models. A numerical procedure
has been developed in order to attain series of results at constant pressure
from simulations of the lattice gas model in the grand canonical ensemble. The
excess properties of the mixtures: volume and enthalpy as the function of the
solute fraction have been studied for different interaction parameters of the
model. Our model is able to reproduce qualitatively well the excess volume and
enthalpy for different aqueous solutions. For the hydrophilic case, we show
that the model is able to reproduce the excess volume and enthalpy of mixtures
of small alcohols and amines. The inert case reproduces the behavior of large
alcohols such as, propanol, butanol and pentanol. For last case (hydrophobic),
the excess properties reproduce the behavior of ionic liquids in aqueous
solution.Comment: 28 pages, 13 figure
Effects Of Changes In Conditioning Regimen And Supportive Care On Outcomes In Patients With Acute Myeloid Leukemia (AML) After Allogeneic Stem Cell Transplantation (Allo-SCT)
Towards Scalable Visual Exploration of Very Large RDF Graphs
In this paper, we outline our work on developing a disk-based infrastructure
for efficient visualization and graph exploration operations over very large
graphs. The proposed platform, called graphVizdb, is based on a novel technique
for indexing and storing the graph. Particularly, the graph layout is indexed
with a spatial data structure, i.e., an R-tree, and stored in a database. In
runtime, user operations are translated into efficient spatial operations
(i.e., window queries) in the backend.Comment: 12th Extended Semantic Web Conference (ESWC 2015
Correlations in Scale-Free Networks: Tomography and Percolation
We discuss three related models of scale-free networks with the same degree
distribution but different correlation properties. Starting from the
Barabasi-Albert construction based on growth and preferential attachment we
discuss two other networks emerging when randomizing it with respect to links
or nodes. We point out that the Barabasi-Albert model displays dissortative
behavior with respect to the nodes' degrees, while the node-randomized network
shows assortative mixing. These kinds of correlations are visualized by
discussig the shell structure of the networks around their arbitrary node. In
spite of different correlation behavior, all three constructions exhibit
similar percolation properties.Comment: 6 pages, 2 figures; added reference
Does native Trypanosoma cruzi calreticulin mediate growth inhibition of a mammary tumor during infection?
Indexación: Web of Science.Background: For several decades now an antagonism between Trypanosoma cruzi infection and tumor development has been detected. The molecular basis of this phenomenon remained basically unknown until our proposal that T. cruzi Calreticulin (TcCRT), an endoplasmic reticulum-resident chaperone, translocated-externalized by the parasite, may mediate at least an important part of this effect. Thus, recombinant TcCRT (rTcCRT) has important in vivo antiangiogenic and antitumor activities. However, the relevant question whether the in vivo antitumor effect of T. cruzi infection is indeed mediated by the native chaperone (nTcCRT), remains open. Herein, by using specific modified anti-rTcCRT antibodies (Abs), we have neutralized the antitumor activity of T. cruzi infection and extracts thereof, thus identifying nTcCRT as a valid mediator of this effect.
Methods: Polyclonal anti-rTcCRT F(ab')(2) Ab fragments were used to reverse the capacity of rTcCRT to inhibit EAhy926 endothelial cell (EC) proliferation, as detected by BrdU uptake. Using these F(ab')(2) fragments, we also challenged the capacity of nTcCRT, during T. cruzi infection, to inhibit the growth of an aggressive mammary adenocarcinoma cell line (TA3-MTXR) in mice. Moreover, we determined the capacity of anti-rTcCRT Abs to reverse the antitumor effect of an epimastigote extract (EE). Finally, the effects of these treatments on tumor histology were evaluated.
Results: The rTcCRT capacity to inhibit ECs proliferation was reversed by anti-rTcCRT F(ab')(2) Ab fragments, thus defining them as valid probes to interfere in vivo with this important TcCRT function. Consequently, during infection, these Ab fragments also reversed the in vivo experimental mammary tumor growth. Moreover, anti-rTcCRT Abs also neutralized the antitumor effect of an EE, again identifying the chaperone protein as an important mediator of this anti mammary tumor effect. Finally, as determined by conventional histological parameters, in infected animals and in those treated with EE, less invasive tumors were observed while, as expected, treatment with F(ab')(2) Ab fragments increased malignancy.
Conclusion: We have identified translocated/externalized nTcCRT as responsible for at least an important part of the anti mammary tumor effect of the chaperone observed during experimental infections with T. cruzi.http://bmccancer.biomedcentral.com/articles/10.1186/s12885-016-2764-
Random graphs with arbitrary degree distributions and their applications
Recent work on the structure of social networks and the internet has focussed
attention on graphs with distributions of vertex degree that are significantly
different from the Poisson degree distributions that have been widely studied
in the past. In this paper we develop in detail the theory of random graphs
with arbitrary degree distributions. In addition to simple undirected,
unipartite graphs, we examine the properties of directed and bipartite graphs.
Among other results, we derive exact expressions for the position of the phase
transition at which a giant component first forms, the mean component size, the
size of the giant component if there is one, the mean number of vertices a
certain distance away from a randomly chosen vertex, and the average
vertex-vertex distance within a graph. We apply our theory to some real-world
graphs, including the world-wide web and collaboration graphs of scientists and
Fortune 1000 company directors. We demonstrate that in some cases random graphs
with appropriate distributions of vertex degree predict with surprising
accuracy the behavior of the real world, while in others there is a measurable
discrepancy between theory and reality, perhaps indicating the presence of
additional social structure in the network that is not captured by the random
graph.Comment: 19 pages, 11 figures, some new material added in this version along
with minor updates and correction
The portrayal and frequency of religion in secular rap music
Title from PDF of title page (University of Missouri--Columbia, viewed on September 10, 2012).The entire thesis text is included in the research.pdf file; the official abstract appears in the short.pdf file; a non-technical public abstract appears in the public.pdf file.Thesis advisor: Dr. Cynthia FrisbyIncludes bibliographical references.M.A. University of Missouri--Columbia 2012."May 2012"Secular rap has arguably become one of the most influential and popular genres in music, and its effects on aspects of American culture, like sexuality (Ward, Hansbrough, & Walker, 2005) and violence (Jones, 1997), have been measured. The way rap music may have potentially influenced the religiosity of its listeners has yet to be explored. This study starts that line of research by measuring the amount of religious references in secular rap songs and examining any possible relationships between the amounts of religious references and how religion is portrayed in those songs. The researcher conducted a content analysis of lyrics from twenty influential rappers. The researcher then compared the portrayal of religion in rap songs released before the death of rapper Tupac Shakur to the songs released after that date. The results indicated a significant relationship between the amount of religious references and the framing of religion, while the researcher found significant negative relationships in how religion was framed after the death of Shakur. The results indicate a need for media effects research on the lyrics of Tupac Shakur to further examine the influence the lyrics have on listeners
String Shooter's overall shape in ambient air
In this article, we study the behaviour of a looped string launched in
ambient air using motorised wheels. We show that the loop, once it reaches its
stationary state, is either in the pulley or the air-lifted state. The
transition between these two distinct states occurs at the so-called takeoff
speed. We prove that this speed differs from one string to another based on its
characteristics. However, it is independent from the loop's length and its
initial launch angle. This speed indeed corresponds to the threshold where air
drag starts compensating for the weight of the string.Comment: 8 pages, 12 figure
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