7,479 research outputs found

    Mechanisms for Lasing with Cold Atoms as the Gain Medium

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    We realize a laser with a cloud of cold rubidium atoms as gain medium, placed in a low-finesse cavity. Three different regimes of laser emission are observed corresponding respectively to Mollow, Raman and Four Wave Mixing mechanisms. We measure an output power of up to 300 μ\muW and present the main properties of these different lasers in each regime

    Treatment of Young Children with HIV Infection: Using Evidence to Inform Policymakers

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    PMCID: PMC3404108This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited

    Chimera States for Coupled Oscillators

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    Arrays of identical oscillators can display a remarkable spatiotemporal pattern in which phase-locked oscillators coexist with drifting ones. Discovered two years ago, such "chimera states" are believed to be impossible for locally or globally coupled systems; they are peculiar to the intermediate case of nonlocal coupling. Here we present an exact solution for this state, for a ring of phase oscillators coupled by a cosine kernel. We show that the stable chimera state bifurcates from a spatially modulated drift state, and dies in a saddle-node bifurcation with an unstable chimera.Comment: 4 pages, 4 figure

    Experimental study of direct photon emission in K- --> pi- pi0 gamma decay using ISTRA+ detector

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    The branching ratio in the charged-pion kinetic energy region of 55 to 90 MeV for the direct photon emission in the K- --> pi- pi0 gamma decay has been measured using in-flight decays detected with the ISTRA+ setup operating in the 25 GeV/c negative secondary beam of the U-70 PS. The value Br(DE)=[0.37+-0.39(stat)+-0.10(syst)]*10^(-5) obtained from the analysis of 930 completely reconstructed events is consistent with the average value of two stopped-kaon experiments, but it differs by 2.5 standard deviations from the average value of three in-flight-kaon experiments. The result is also compared with recent theoretical predictions.Comment: 13 pages, 8 figure

    Elastic Scattering and Direct Detection of Kaluza-Klein Dark Matter

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    Recently a new dark matter candidate has been proposed as a consequence of universal compact extra dimensions. It was found that to account for cosmological observations, the masses of the first Kaluza-Klein modes (and thus the approximate size of the extra dimension) should be in the range 600-1200 GeV when the lightest Kaluza-Klein particle (LKP) corresponds to the hypercharge boson and in the range 1 - 1.8 TeV when it corresponds to a neutrino. In this article, we compute the elastic scattering cross sections between Kaluza-Klein dark matter and nuclei both when the lightest Kaluza-Klein particle is a KK mode of a weak gauge boson, and when it is a neutrino. We include nuclear form factor effects which are important to take into account due to the large LKP masses favored by estimates of the relic density. We present both differential and integrated rates for present and proposed Germanium, NaI and Xenon detectors. Observable rates at current detectors are typically less than one event per year, but the next generation of detectors can probe a significant fraction of the relevant parameter space.Comment: 23 pages, 11 figures; v2,v3: Ref. added, discussion improved, conclusions unchanged. v4: Introduction was expanded to be more appropriate for non experts. Various clarifications added in the text. Version to be published in New Journal of Physic

    New summing algorithm using ensemble computing

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    We propose an ensemble algorithm, which provides a new approach for evaluating and summing up a set of function samples. The proposed algorithm is not a quantum algorithm, insofar it does not involve quantum entanglement. The query complexity of the algorithm depends only on the scaling of the measurement sensitivity with the number of distinct spin sub-ensembles. From a practical point of view, the proposed algorithm may result in an exponential speedup, compared to known quantum and classical summing algorithms. However in general, this advantage exists only if the total number of function samples is below a threshold value which depends on the measurement sensitivity.Comment: 13 pages, 0 figures, VIth International Conference on Quantum Communication, Measurement and Computing (Boston, 2002

    Prediction of impending type 1 diabetes through automated dual-label measurement of proinsulin:C-peptide ratio

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    Background : The hyperglycemic clamp test, the gold standard of beta cell function, predicts impending type 1 diabetes in islet autoantibody-positive individuals, but the latter may benefit from less invasive function tests such as the proinsulin: C-peptide ratio (PI:C). The present study aims to optimize precision of PI:C measurements by automating a dual-label trefoil-type time-resolved fluorescence immunoassay (TT-TRFIA), and to compare its diagnostic performance for predicting type 1 diabetes with that of clamp-derived C-peptide release. Methods : Between-day imprecision (n = 20) and split-sample analysis (n = 95) were used to compare TT-TRFIA (Auto Delfia, Perkin-Elmer) with separate methods for proinsulin (in-house TRFIA) and C-peptide (Elecsys, Roche). High-risk multiple autoantibody-positive firstdegree relatives (n = 49; age 5-39) were tested for fasting PI:C, HOMA2-IR and hyperglycemic clamp and followed for 20-57 months (interquartile range). Results : TT-TRFIA values for proinsulin, C-peptide and PI:C correlated significantly (r(2) = 0.96-0.99; P<0.001) with results obtained with separate methods. TT-TRFIA achieved better between-day % CV for PI:C at three different levels (4.5-7.1 vs 6.7-9.5 for separate methods). In high-risk relatives fasting PI:C was significantly and inversely correlated ( r(s) = -0.596; P<0.001) with first-phase C-peptide release during clamp ( also with second phase release, only available for age 12-39 years; n = 31), but only after normalization for HOMA2-IR. In ROC- and Cox regression analysis, HOMA2-IR-corrected PI:C predicted 2-year progression to diabetes equally well as clamp-derived C-peptide release. Conclusions : The reproducibility of PI:C benefits from the automated simultaneous determination of both hormones. HOMA2-IR-corrected PI:C may serve as a minimally invasive alternative to the more tedious hyperglycemic clamp test
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