An Underappreciated Radiation Hazard from High Voltage Electrodes in Vacuum

The use of high voltage (HV) electrodes in vacuum is commonplace in physics laboratories. In such systems, it has long been known that electron emission from an HV cathode can lead to bremsstrahlung X-rays; indeed, this is the basic principle behind the operation of standard X-ray sources. However, in laboratory setups where X-ray production is not the goal and no electron source is deliberately introduced, field-emitted electrons accelerated by HV can produce X-rays as an unintended hazardous byproduct. Both the level of hazard and the safe operating regimes for HV vacuum electrode systems are not widely appreciated, at least in university laboratories. A reinforced awareness of the radiation hazards associated with vacuum HV setups would be beneficial. We present a case study of a HV vacuum electrode device operated in a university atomic physics laboratory. We describe the characterisation of the observed X-ray radiation, its relation to the observed leakage current in the device, the steps taken to contain and mitigate the radiation hazard, and suggest safety guidelines.Comment: Submitted to Health Physic

Site U1334

Integrated Ocean Drilling Program (IODP) Site U1334 (7°59.998?N, 131°58.408?W; 4799 meters below sea level [mbsl]) (Fig. F1; Table T1) is located ~380 km southeast of previously drilled Ocean Drilling Program (ODP) Site 1218 (~42 Ma crust) in the central area drilled during the Pacific Equatorial Age Transect (PEAT) program (IODP Expedition 320/321). Site U1334 (~38 Ma crust) is situated ~100 km north of the Clipperton Fracture Zone on abyssal hill topography draped with ~280 m sediment (Fig. F2). The fabric of the abyssal hills within the sites is oriented either due north or slightly east of due north.Water depth in the vicinity of Site U1334 ranges between 5.0 and 5.1 km for the depressions between the abyssal hills. The abyssal hills range between 4.70 and 4.85 km water depth and generally show a thicker and more consistent sediment cover than the basins. In fact, a significant amount of the bathymetric difference between hills and basins is controlled by the amount of sediment cover. The comparison of sediment thickness and clarity of seismic sections led us to select a location on the middle elevation of one of the abyssal plateaus.Site U1334 sediments were estimated to have been deposited on top of late middle Eocene crust with an age of ~38 Ma and target the events bracketing the Eocene–Oligocene transition with the specific aim of recovering carbonate-bearing sediments of latest Eocene age prior to a large deepening of the calcium carbonate compensation depth (CCD) that occurred during this greenhouse to icehouse transition (Kennett and Shackleton, 1976; Miller et al., 1991; Zachos et al., 1996; Coxall et al., 2005). The Eocene–Oligocene transition experienced the most dramatic deepening of the Pacific CCD during the Paleogene (van Andel, 1975), which has now been shown by Coxall et al. (2005) to coincide with a rapid stepwise increase in benthic oxygen stable isotope ratios, interpreted to reflect a combination of growth of the Antarctic ice sheet and decrease in deepwater temperatures (DeConto et al., 2008; Liu et al., 2009).<br/

Energy distribution modulation by mechanical design for electrochemical jet processing techniques

The increasing demand for optimised component surfaces with enhanced chemical and geometric complexity is a key driver in the manufacturing technology required for advanced surface production. Current methodologies cannot create complex surfaces in an efficient and scalable manner in robust engineering materials. Hence, there is a need for advanced manufacturing technologies which overcome this. Current technologies are limited by resolution, geometric flexibility and mode of energy delivery. By addressing the fundamental limitations of electrochemical jetting techniques through modulation of the current density distribution by mechanical design, significant improvements to the electrochemical jet process methods are presented. A simplified 2D stochastic model was developed with the ability to vary current density distribution to assess the effects of nozzle-tip shape changes. The simulation demonstrated that the resultant profile was found to be variable from that of a standard nozzle. These nozzle-tip modifications were then experimentally tested finding a high degree of variance was possible in the machined profile. Improvements such as an increase in side-wall steepness of 162% are achieved over a standard profile, flat bases to the cut profile and a reduction of profile to surface inter-section radius enable the process to be analogous to traditional milling profiles. Since electrode design can be rapidly modified EJP is shown to be a flexible process capable of varied and complex meso-scale profile creation. Innovations presented here in the modulation of resistance in-jet have enabled electrochemical jet processes to become a viable, top-down, single-step method for applying complex surfaces geometries unachievable by other means

A simple rapid process for semi-automated brain extraction from magnetic resonance images of the whole mouse head

Background: Magnetic resonance imaging (MRI) is a well-developed technique in neuroscience. Limitations in applying MRI to rodent models of neuropsychiatric disorders include the large number of animals required to achieve statistical significance, and the paucity of automation tools for the critical early step in processing, brain extraction, which prepares brain images for alignment and voxel-wise statistics. New Method: This novel timesaving automation of template-based brain extraction (“skull-stripping”) is capable of quickly and reliably extracting the brain from large numbers of whole head images in a single step. The method is simple to install and requires minimal user interaction. Results: This method is equally applicable to different types of MR images. Results were evaluated with Dice and Jacquard similarity indices and compared in 3D surface projections with other stripping approaches. Statistical comparisons demonstrate that individual variation of brain volumes are preserved. Comparison with Existing Methods: A downloadable software package not otherwise available for extraction of brains from whole head images is included here. This software tool increases speed, can be used with an atlas or a template from within the dataset, and produces masks that need little further refinement. Conclusions: Our new automation can be applied to any MR dataset, since the starting point is a template mask generated specifically for that dataset. The method reliably and rapidly extracts brain images from whole head images, rendering them useable for subsequent analytical processing. This software tool will accelerate the exploitation of mouse models for the investigation of human brain disorders by MRI

The interaction of knowledge sources in word sense disambiguation

Word sense disambiguation (WSD) is a computational linguistics task likely to benefit from the tradition of combining different knowledge sources in artificial in telligence research. An important step in the exploration of this hypothesis is to determine which linguistic knowledge sources are most useful and whether their combination leads to improved results. We present a sense tagger which uses several knowledge sources. Tested accuracy exceeds 94% on our evaluation corpus.Our system attempts to disambiguate all content words in running text rather than limiting itself to treating a restricted vocabulary of words. It is argued that this approach is more likely to assist the creation of practical systems