382 research outputs found

    Measurement of the production of charm jets tagged with D0^{0} mesons in pp collisions at s\sqrt{s}= 7 TeV

    Full text link
    The production of charm jets in proton-proton collisions at a center-of-mass energy of s=7\sqrt{s}=7 TeV was measured with the ALICE detector at the CERN Large Hadron Collider. The measurement is based on a data sample corresponding to a total integrated luminosity of 6.236.23 nb1{\rm nb}^{-1}, collected using a minimum-bias trigger. Charm jets are identified by the presence of a D0^0 meson among their constituents. The D0^0 mesons are reconstructed from their hadronic decay D0^0\rightarrowKπ+^{-}\pi^{+}. The D0^0-meson tagged jets are reconstructed using tracks of charged particles (track-based jets) with the anti-kTk_{\mathrm{T}} algorithm in the jet transverse momentum range 5<pT,jetch<305<p_{\rm{T,jet}}^{\mathrm{ch}}<30 GeV/c{\rm GeV/}c and pseudorapidity ηjet<0.5|\eta_{\rm jet}|<0.5. The fraction of charged jets containing a D0^0-meson increases with pT,jetchp_{\rm{T,jet}}^{\rm{ch}} from 0.042±0.004(stat)±0.006(syst)0.042 \pm 0.004\, \mathrm{(stat)} \pm 0.006\, \mathrm{(syst)} to 0.080±0.009(stat)±0.008(syst)0.080 \pm 0.009\, \rm{(stat)} \pm 0.008\, \rm{(syst)}. The distribution of D0^0-meson tagged jets as a function of the jet momentum fraction carried by the D0^0 meson in the direction of the jet axis (zchz_{||}^{\mathrm{ch}}) is reported for two ranges of jet transverse momenta, 5<pT,jetch<155<p_{\rm{T,jet}}^{\rm{ch}}<15 GeV/c{\rm GeV/}c and 15<pT,jetch<3015<p_{\rm{T,jet}}^{\rm{ch}}<30 GeV/c{\rm GeV/}c in the intervals 0.2<zch<1.00.2<z_{||}^{\rm{ch}}<1.0 and 0.4<zch<1.00.4<z_{||}^{\rm{ch}}<1.0, respectively. The data are compared with results from Monte Carlo event generators (PYTHIA 6, PYTHIA 8 and Herwig 7) and with a Next-to-Leading-Order perturbative Quantum Chromodynamics calculation, obtained with the POWHEG method and interfaced with PYTHIA 6 for the generation of the parton shower, fragmentation, hadronisation and underlying event.Comment: 29 pages, 8 captioned figures, 3 tables, authors from page 24, published version, figures at http://alice-publications.web.cern.ch/node/525

    Brain perfusion imaging with voxel-based analysis in secondary progressive multiple sclerosis patients with a moderate to severe stage of disease: a boon for the workforce

    Get PDF
    Background: The present study was carried out to evaluate cerebral perfusion in multiple sclerosis (MS) patients with a moderate to severe stage of disease. Some patients underwent hyperbaric oxygen therapy (HBOT) and brain perfusion between before and after that was compared. Methods: We retrospectively reviewed 25 secondary progressive (SP)-MS patients from the hospital database. Neurological disability evaluated by Expanded Disability Status Scale Score (EDSS). Brain perfusion was performed by (99 m) Tc-labeled bicisate (ECD) brain SPECT and the data were compared using statistical parametric mapping (SPM). In total, 16 patients underwent HBOT. Before HBOT and at the end of 20 sessions of oxygen treatment, 99mTc-ECD brain perfusion single photon emission computed tomography (SPECT) was performed again then the results were evaluated and compared. Brain perfusion was performed by (99 m) Tc-labeled bicisate (ECD) brain SPECT and the data were compared using statistical parametric mapping (SPM). Results: A total of 25 SP-MS patients, 14 females (56 %) and 11 males (44 %) with a mean age of 38.92 ± 11. 28 years included in the study. The mean disease duration was 8.70 ± 5.30 years. Of the 25 patients, 2 (8 %) had a normal SPECT and 23 (92 %) had abnormal brain perfusion SPECT studies. The study showed a significant association between severity of perfusion impairment with disease duration and also with EDSS (P <0.05). There was a significant improvement in pre- and post-treatment perfusion scans (P <0.05), but this did not demonstrate a significant improvement in the clinical subjective and objective evaluation of patients (P >0.05). Conclusions: This study depicted decreased cerebral perfusion in SP-MS patients with a moderate to severe disability score and its association with clinical parameters. Because of its accessibility, rather low price, practical ease, and being objective quantitative information, brain perfusion SPECT can be complementing to other diagnostic modalities such as MRI and clinical examinations in disease surveillance and monitoring. The literature on this important issue is extremely scarce, and follow up studies are required to assess these preliminary results
    corecore