Comment le technicien en radiologie médicale (TRM) adapte-t-il sa prise en charge d'un jeune adulte en radiothérapie ?: travail de Bachelor

Notre travail de Bachelor porte sur l’adaptation du TRM lorsqu’il prend en charge un jeune adulte en radiothérapie. Nous voulions avoir l’avis du TRM sur ce sujet pour comprendre et analyser les moyens qu’il met en oeuvre pour prendre en charge ce type de patient. Cette population qui n’est pas très courante dans un service de radiothérapie a des caractéristiques particulières. Nous avons donc analysé le jeune adulte du point de vue du TRM, pour mieux comprendre la situation qu’il vit et ses enjeux

Acrodermatitis enteropática: tratamiento con Zinc

Se presenta un nuevo caso de Acrodermatitis Enteropática en un lactante de 2,5 meses de vida, fruto de embarazo gemelar bivitelino pretérmino (36 S), de aparición gradual desde los 15 días de vida. Había seguido lactancia artificial exclusivamente desde su nacimiento, al igual que su hermano gemelo que no presentó la enfermedad. Entre los exámenes complementarios destacaba una importante hipozincemia, fosfatasas alcalinas descendidas, alteraciones en la inmunidad celular, rasgos de inmadurez cerebral en el EEG y discreta atrofia vellositaria en la muestra biópsica intestinal. El Tratamiento con sulfato de Zinc a la dosis de 10 mg/Kg/día hizo remitir el cuadro clínico y analítico en pocos días. A los 4 meses de edad abandonó el tratamiento, reapareciendo a los 22 días los síntomas digestivos y cutáneos; la zincemia en ese momento era elevada (175 mcg/dl). Esta falta de relación entre la zincemia y la clínica sugiere que en la Acrodermatitis Enteropática el defecto de transporte del Zn afecta no sólo al enterocito sino también a otras células del organismo y que el criterio para mantener el tratamiento y fijar la dosis debe ser clínico y no analítico

Why is Pharma So Scared of Psychiatric Drug Discovery?

The 1950s heralded a golden age for psychiatric drug discovery;for the first time, compounds capable of treating serious mentaldisturbances were found that, despite their shortcomings, provedthe pharmacotherapy of mental disorders was both possibleand effective. Not only did these early treatments unlock theVictorian asylums and allow a more humane attitude to mentalillness, they also led to the founding of modern neuroscienceapproaches to understanding the function and dysfunctionof the most complex object in the universe- the human brai

Prevalence Of Refractive Errors Among Medical Students In Benghazi University

Background: Refractive errors (REs) are common and continue to increase globally. Uncorrected REs are the second leading cause of preventable blindness and the most common cause of visual impairment. Aim of the study: The objective of the study was to determine the prevalence of refractive errors and its association with age, gender among the students of Medical Sciences colleges in Benghazi university, Libya. Patients & Methods: This cross sectional study was performed in the department of ophthalmology, Benghazi university during the period from December 2023 to March 2024 (4 months). The target population of the study was 200 students aged 19-25 years, of Medical Sciences colleges in Benghazi university. The selected students were invited to participate in the study, students already had pre-existing ocular causes of decreased visual acuity and so were not eligible for the study were excluded from the study Results: the age was 23.3. ± 1.02 years, patients were 116 (58%) females and 84 (42%) females. The overall prevalence rate of myopia was 58.75%, hypermetropia was 2.5% and astigmatism was 37.75%. myopia was recoded in 20 males versus 27 females, hypermetropia was recorded in one male versus one female, while Astigmatism was recorded in 16 males versus 15 females. refractive errors were more in the age group (23-25 years). Conclusion: Prevalence rates of myopia in medical students are found to be quite high myopia is the predominant refractive error among the medical students and correction of refractive error could benefit the society and nation at large

A reassessment of prebiotically relevant chemical agents for the activation of α-amino acids and peptides

International audienceFrom an origin-of-life perspective, processes able to provide energy to feed self-organizing systems are required for the formation of their own components but also to maintain a far from equilibrium state essential for the system to remain under kinetic control. α-Amino acid N-carboxyanhydrides (NCAs) and 5(4H)-oxazolones represent activated intermediates of the chemistry of peptides that may be involved in the self-organization of life and in the evolution of translation. An experimental survey of previously published activating agents has been carried out using the epimerization associated with the transient formation of 5(4H)-oxazolones as a tool to monitor their potential to promote strong activation. None of reagents investigated in this survey proved to be totally satisfactory demonstrating that the identification of activation processes remains a crucial goal in this field

Synchronization of clocks

Peer reviewedPostprin

The Odyssey of Dental Anxiety: From Prehistory to the Present. A Narrative Review

Dental anxiety (DA) can be considered as a universal phenomenon with a high prevalence worldwide; DA and pain are also the main causes for medical emergencies in the dental office, so their prevention is an essential part of patient safety and overall quality of care. Being DA and its consequences closely related to the fight-or-flight reaction, it seems reasonable to argue that the odyssey of DA began way back in the distant past, and has since probably evolved in parallel with the development of fight-or-flight reactions, implicit memory and knowledge, and ultimately consciousness. Basic emotions are related to survival functions in an inseparable psychosomatic unity that enable an immediate response to critical situations rather than generating knowledge, which is why many anxious patients are unaware of the cause of their anxiety. Archeological findings suggest that humans have been surprisingly skillful and knowledgeable since prehistory. Neanderthals used medicinal plants; and relics of dental tools bear witness to a kind of Neolithic proto-dentistry. In the two millennia BC, Egyptian and Greek physicians used both plants (such as papaver somniferum) and incubation (a forerunner of modern hypnosis, e.g., in the sleep temples dedicated to Asclepius) in the attempt to provide some form of therapy and painless surgery, whereas modern scientific medicine strongly understated the role of subjectivity and mind-body approaches until recently. DA has a wide range of causes and its management is far from being a matter of identifying the ideal sedative drug. A patient's proper management must include assessing his/her dental anxiety, ensuring good communications, and providing information (iatrosedation), effective local anesthesia, hypnosis, and/or a wise use of sedative drugs where necessary. Any weak link in this chain can cause avoidable suffering, mistrust, and emergencies, as well as having lifelong psychological consequences. Iatrosedation and hypnosis are no less relevant than drugs and should be considered as primary tools for the management of DA. Unlike pharmacological sedation, they allow to help patients cope with the dental procedure and also overcome their anxiety: achieving the latter may enable them to face future dental care autonomously, whereas pharmacological sedation can only afford a transient respite

The contribution of [1H] magnetic resonance spectroscopy to the study of excitation-inhibition in autism

Autism spectrum disorder (ASD) affects over 1:100 of the population and costs the UK more than £32bn and the USA more than $175bn (£104bn) annually. Its core symptoms are social and communication difficulties, repetitive behaviours and sensory hyper- or hypo-sensitivities. A highly diverse phenotypic presentation likely reflects its etiological heterogeneity and makes finding treatment targets for ASD challenging. In addition, there are no means to identify biologically responsive individuals who may benefit from specific interventions. There is hope however, and in this review we consolidate how findings from magnetic resonance spectroscopy (MRS) add to the evidence that differences in the brain's excitatory glutamate and inhibitory γ-aminobutyric acid (GABA) balance may be both a key biomarker and a tractable treatment target in ASD.<br/