An Overview of Mobile Ad Hoc Networks for the Existing Protocols and Applications

Mobile Ad Hoc Network (MANET) is a collection of two or more devices or nodes or terminals with wireless communications and networking capability that communicate with each other without the aid of any centralized administrator also the wireless nodes that can dynamically form a network to exchange information without using any existing fixed network infrastructure. And it's an autonomous system in which mobile hosts connected by wireless links are free to be dynamically and some time act as routers at the same time, and we discuss in this paper the distinct characteristics of traditional wired networks, including network configuration may change at any time, there is no direction or limit the movement and so on, and thus needed a new optional path Agreement (Routing Protocol) to identify nodes for these actions communicate with each other path, An ideal choice way the agreement should not only be able to find the right path, and the Ad Hoc Network must be able to adapt to changing network of this type at any time. and we talk in details in this paper all the information of Mobile Ad Hoc Network which include the History of ad hoc, wireless ad hoc, wireless mobile approaches and types of mobile ad Hoc networks, and then we present more than 13 types of the routing Ad Hoc Networks protocols have been proposed. In this paper, the more representative of routing protocols, analysis of individual characteristics and advantages and disadvantages to collate and compare, and present the all applications or the Possible Service of Ad Hoc Networks.Comment: 24 Pages, JGraph-Hoc Journa

Patient preferences for the pharmacological treatment of osteoarthritis using adaptive choice-based conjoint (ACBC) analysis: A pilot study

Background: Patient preferences for pharmaceutical treatment of osteoarthritis have been investigated using Conjoint Analysis. Studies have identified the importance of side effects in determining preferences, but noted that methodological limitations precluded further investigation of additional attributes such as hepatic and renal toxicity. Objective: Following on from a feasibility study of adaptive choice-based conjoint (ACBC) analysis, the aim of this study was to evaluate 8 medication attributes for the pharmaceutical treatment of osteoarthritis (OA). Setting and Participants: Eleven participants were recruited from members of a Research Users’ Group (RUG) who had been diagnosed with osteoarthritis. RUG members individually complete the ACBC task. Main outcome measures: The relative importance of each attribute and the utilities (part-worth) of each level of each attribute were estimated using ACBC built-in Hierarchical Bayes (HB). Results: The combined relative importance of the 4 risk side-effect attributes when selecting osteoarthritis medication (kidney and liver side effects, heart attack and stroke side effects, stomach side effects and addiction) was 66% while the effectiveness attribute accounted for 8% of the relative importance of the medication decision. Conclusions: In this study, the gap between relative importance of 4 side-effect attributes and expected benefit was 66% vs 8%. These preliminary findings indicate that OA patients are most concerned with the avoidance of adverse events and that there is a threshold above which expected benefit has little impact on patients’ medication preferences. The study highlights methodological features of ACBC that may be useful more generally in health services research, but the results must be interpreted in conjunction with the study limitations

Striking enhancement at the site of radiation for nivolumab-induced Stevens-Johnson syndrome

Stevens-Johnson syndrome is a rare adverse cutaneous drug reaction characterized by epidermal detachment of <10% body surface area with an average mortality rate of 1-5%. The mechanism of SJS is not fully understood. Nivolumab is a monoclonal antibody directed against programmed cell death-1 protein (PD-1), a receptor with immune checkpoint inhibitory and antineoplastic activities. We present a case of SJS in a patient being treated with anti-PD-1 therapy nivolumab for metastatic squamous cell carcinoma of the oropharynx. This case is unusual because of the severe accentuation with striking enhancement at his prior radiation site and in the cutaneous region with heavier tumor burden from his metastatic disease. This reaction may give insight to the underlying pathophysiology of SJS, suggesting that immune checkpoint inhibitors can activate T-cells to target keratinocytes and that external factors may be involved in creating distinct epitopes for T-cell recognition. We hope this case adds to the body of knowledge in the pathogenesis of Stevens-Johnson syndrome and cutaneous adverse events seen with checkpoint inhibitors

On the generalized Hartley-Hilbert and Fourier-Hilbert transforms

In this paper, we discuss Hartley-Hilbert and Fourier-Hilbert transforms on a certain class of generalized functions. The extended transforms considered in this article are shown to be well-defined, one-to-one, linear and continuous mappings with respect to δ and Δ convergence. Certain theorems are also established

Contra continuity on weak structure spaces

We introduce some contra continuous functions in weak structure spaces such as contra (M,w)-continuous functions, contra (alpha(m),w)-continuous functions, contra (sigma(m),w)-continuous functions, contra (pi(m),w)-continuous functions and contra (beta(m),w)-continuous functions. We investigate their characterization and relationships among such functions