Principal component analysis of atrial fibrillation: Inclusion of posterior ECG leads does not improve correlation with left atrial activity

Background Lead V? is routinely analysed due to its large amplitude AF waveform. V? correlates strongly with right atrial activity but only moderately with left atrial activity. Posterior lead V? correlates strongest with left atrial activity. Aims (1) To establish whether surface dominant AF frequency (DAF) calculated using principal component analysis (PCA) of a modified 12-lead ECG (including posterior leads) has a stronger correlation with left atrial activity compared to the standard ECG. (2) To assess the contribution of individual ECG leads to the AF principal component in both ECG configurations. Methods Patients were assigned to modified or standard ECG groups. In the modified ECG, posterior leads V? and V? replaced V? and V?. AF waveform was extracted from one-minute surface ECG recordings using PCA. Surface DAF was correlated with intracardiac DAF from the high right atrium (HRA), coronary sinus (CS) and pulmonary veins (PVs). Results 96 patients were studied. Surface DAF from the modified ECG did not have a stronger correlation with left atrial activity compared to the standard ECG. Both ECG configurations correlated strongly with HRA, CS and right PVs but only moderately with left PVs. V? contributed most to the AF principal component in both ECG configurations

Effect of catheter ablation on quality of life in patients with atrial fibrillation and its correlation with arrhythmia outcome

Objective To assess the effect of catheter ablation on atrial fibrillation (AF) symptoms and quality of life (QoL). Methods Patients with AF scheduled for ablation were recruited. Pulmonary vein isolation (PVI) was performed and complex fractionated atrial electrogram (CFAE)±linear ablation undertaken in patients in AF despite PVI. QoL and AF symptoms were assessed using SF-36 V2 and Atrial Fibrillation Effect on Quality-of-Life (AFEQT) questionnaires before and 3 months after ablation. Change in QoL scores after ablation was correlated with clinical parameters and the extent of ablation. Magnitude of QoL change was compared between AFEQT and SF-36 physical component summary (PCS) and mental component summary (MCS) scores and correlated with arrhythmia outcome. Results 80 patients were studied. Summative and individual health scores for both AFEQT (51.5±22.0 vs 81.3±18.2; p<0.01) and SF-36 (PCS 43.3±10.5 vs 47.9±11.3; p<0.01 and MCS 45.0±11.5 vs 51.5±9.4; p<0.01) improved significantly in patients who maintained sinus rhythm after ablation, but not in those with recurrent AF. Improvement in AFEQT (25.4±19) was significantly greater than change in PCS (6.8±6.4; p<0.01) and MCS (8.5±7.9; p<0.01) scores and correlated more closely with arrhythmia outcome (AFEQT r=0.55; PCS r=0.26; MCS r=0.30). Conclusions Patients who maintained sinus rhythm after ablation had a significant improvement in AF symptoms and QoL; however, no improvement was observed in patients with recurrent AF. QoL change after ablation did not correlate with baseline clinical parameters or ablation strategy. AF specific QoL scales are more responsive to change and correlate better with ablation outcome

Video analysis of events within chemical sensor networks

This paper describes how we deploy video surveillance techniques to monitor the activities within a sensor network in order to detect environmental events. This approach combines video and sensor networks in a completely different way to what would be considered the norm. Sensor networks consist of a collection of autonomous, self-powered nodes which sample their environment to detect anything from chemical pollutants to atypical sound patterns which they report through an ad hoc network. In order to reduce power consumption nodes have the capacity to communicate with neighbouring nodes only. Typically these communications are via radio waves but in this paper the sensor nodes communicate to a base station through patterns emitted by LEDs and captured by a video camera. The LEDs are chemically coated to react to their environment and on doing so emit light which is then picked up by video analysis. There are several advantages to this approach and to demonstrate we have constructed a controlled test environment. In this paper we introduce and briefly describe this environment and the sensor nodes but focus mainly on the video capture, image processing and data visualisation techniques used to indicate these events to a user monitoring the network

Non-invasive estimation of left atrial dominant frequency in atrial fibrillation from different electrode sites: Insight from body surface potential mapping

© 2014, CardioFront LLC. All rights reserved. The dominant driving sources of atrial fibrillation are often found in the left atrium, but the expression of left atrial activation on the body surface is poorly understood. Using body surface potential mapping and simultaneous invasive measurements of left atrial activation our aim was to describe the expression of the left atrial dominant fibrillation frequency across the body surface. 20 patients in atrial fibrillation were studied. The spatial distributions of the dominant atrial fibrillation frequency across anterior and posterior sites on the body surface were quantified. Their relationship with invasive left atrial dominant fibrillation frequency was assessed by linear regression analysis, and the coefficient of determination was calculated for each body surface site. The correlation between intracardiac and body surface dominant frequency was significantly higher with posterior compared with anterior sites (coefficient of determination 67±8% vs 48±2%,

Sensor node localisation using a stereo camera rig

In this paper, we use stereo vision processing techniques to detect and localise sensors used for monitoring simulated environmental events within an experimental sensor network testbed. Our sensor nodes communicate to the camera through patterns emitted by light emitting diodes (LEDs). Ultimately, we envisage the use of very low-cost, low-power, compact microcontroller-based sensing nodes that employ LED communication rather than power hungry RF to transmit data that is gathered via existing CCTV infrastructure. To facilitate our research, we have constructed a controlled environment where nodes and cameras can be deployed and potentially hazardous chemical or physical plumes can be introduced to simulate environmental pollution events in a controlled manner. In this paper we show how 3D spatial localisation of sensors becomes a straightforward task when a stereo camera rig is used rather than a more usual 2D CCTV camera

Carbon dioxide accounting:2014 Commonwealth Games Atheletes’ Village

A spreadsheet-based tool for whole-life carbon dioxide accounting of soil remediation projects has been created. The tool carries out whole-life analysis of projects, including supply chain emissions. It was applied to the Glasgow 2014 Commonwealth Games Athletes' Village remediation project, for which a calculated total ‘carbon footprint’ of 2328 t of carbon dioxide equivalent emission (tCO2e) was obtained. This is 71 tCO2e/ha of the site or 13·3 kgCO2e/t whole life of soil treated. These figures are not comparable with those reported for other projects, which have typically not included supply chain emissions. Fuel use was the main contributor to emissions, but the contribution made by staff transport and carbon dioxide embodied in construction plant was also found to be significant. A comparison was made with an excavate and disposal (E&D) approach, which required considerable use of estimation for the hypothetical E&D. However, it was determined that the carbon footprint of E&D may have been 14% higher than the soil washing actually used. It was concluded that fuel efficiency would be key to future reduction of the carbon footprint of remediation projects, that the accounting tool would be useful for ongoing project management, and its application over time could lead to a database of values for optioneering at the process design stage

The Megaparsec-Scale X-ray Jet of the BL Lac Object OJ287

We present an X-ray image of the BL Lacertae object OJ287 revealing a long jet, curved by 55 degrees and extending 20", or 90 kpc from the nucleus. This de-projects to >1 Mpc based on the viewing angle on parsec scales. Radio emission follows the general X-ray morphology but extends even farther from the nucleus. The upper limit to the isotropic radio luminosity, ~2E24 W/Hz, places the source in the Fanaroff-Riley 1 (FR 1) class, as expected for BL Lac objects. The spectral energy distribution indicates that the extended X-ray emission is from inverse Compton scattering of cosmic microwave background photons. In this case, the derived magnetic field is B ~ 5 microGauss, the minimum electron energy is 7-40 m_e c^2, and the Doppler factor is delta ~ 8 in a knot 8" from the nucleus. The minimum total kinetic power of the jet is 1-2E45 erg/s. Upstream of the bend, the width of the X-ray emission in the jet is about half the projected distance from the nucleus. This implies that the highly relativistic bulk motion is not limited to an extremely thin spine, as has been proposed previously for FR 1 sources. The bending of the jet, the deceleration of the flow from parsec to kiloparsec scales, and the knotty structure can all be caused by standing shocks inclined by ~7 degrees to the jet axis. Moving shocks resulting from major changes in the flow properties can also reproduce the knotty structure, but such a model does not explain as many of the observational details.Comment: Accepted for publication in the Astrophysical Journa

Direct Observations of the Ionizing Star in the UC HII Region G29.96-0.02: A Strong Constraint on the Stellar Birth Line for Massive Stars

We have observed the ultracompact HII region G29.96-0.02 in the near infrared J, H, and K bands and in the Br-gamma line. By comparison with radio observations, we determine that the extinction to the nebula is AK = 2.14 with a 3 sigma uncertainty of 0.25. We identify the ionizing star and determine its intrinsic K magnitude. The star does not have an infrared excess and so appears to be no longer accreting. The K magnitude and the bolometric luminosity allow us to place limits on the location of the ionizing star in the HR diagram. The 3 sigma upper limit on the effective temperature of the ionizing star is 42500 K. We favor a luminosity appropriate for star with a mass in excess of about 60 solar masses. The limit on the temperature and luminosity exclude stars on the ZAMS and stars within 10^6 yr of the ZAMS. Since the age of the UC HII region is estimated to be only about 10^5 yr, we suggest that this is direct evidence that the stellar birth line for massive stars at twice solar metallicity must be significantly redder than the ZAMS.Comment: 42 pages; LaTex; 11 Postscript figures; accepted for publication in Ap