1,011 research outputs found

    Biodiversity Loss and the Taxonomic Bottleneck: Emerging Biodiversity Science

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    Human domination of the Earth has resulted in dramatic changes to global and local patterns of biodiversity. Biodiversity is critical to human sustainability because it drives the ecosystem services that provide the core of our life-support system. As we, the human species, are the primary factor leading to the decline in biodiversity, we need detailed information about the biodiversity and species composition of specific locations in order to understand how different species contribute to ecosystem services and how humans can sustainably conserve and manage biodiversity. Taxonomy and ecology, two fundamental sciences that generate the knowledge about biodiversity, are associated with a number of limitations that prevent them from providing the information needed to fully understand the relevance of biodiversity in its entirety for human sustainability: (1) biodiversity conservation strategies that tend to be overly focused on research and policy on a global scale with little impact on local biodiversity; (2) the small knowledge base of extant global biodiversity; (3) a lack of much-needed site-specific data on the species composition of communities in human-dominated landscapes, which hinders ecosystem management and biodiversity conservation; (4) biodiversity studies with a lack of taxonomic precision; (5) a lack of taxonomic expertise and trained taxonomists; (6) a taxonomic bottleneck in biodiversity inventory and assessment; and (7) neglect of taxonomic resources and a lack of taxonomic service infrastructure for biodiversity science. These limitations are directly related to contemporary trends in research, conservation strategies, environmental stewardship, environmental education, sustainable development, and local site-specific conservation. Today’s biological knowledge is built on the known global biodiversity, which represents barely 20% of what is currently extant (commonly accepted estimate of 10 million species) on planet Earth. Much remains unexplored and unknown, particularly in hotspots regions of Africa, South Eastern Asia, and South and Central America, including many developing or underdeveloped countries, where localized biodiversity is scarcely studied or described. ‘‘Backyard biodiversity’’, defined as local biodiversity near human habitation, refers to the natural resources and capital for ecosystem services at the grassroots level, which urgently needs to be explored, documented, and conserved as it is the backbone of sustainable economic development in these countries. Beginning with early identification and documentation of local flora and fauna, taxonomy has documented global biodiversity and natural history based on the collection of ‘‘backyard biodiversity’’ specimens worldwide. However, this branch of science suffered a continuous decline in the latter half of the twentieth century, and has now reached a point of potential demise. At present there are very few professional taxonomists and trained local parataxonomists worldwide, while the need for, and demands on, taxonomic services by conservation and resource management communities are rapidly increasing. Systematic collections, the material basis of biodiversity information, have been neglected and abandoned, particularly at institutions of higher learning. Considering the rapid increase in the human population and urbanization, human sustainability requires new conceptual and practical approaches to refocusing and energizing the study of the biodiversity that is the core of natural resources for sustainable development and biotic capital for sustaining our life-support system. In this paper we aim to document and extrapolate the essence of biodiversity, discuss the state and nature of taxonomic demise, the trends of recent biodiversity studies, and suggest reasonable approaches to a biodiversity science to facilitate the expansion of global biodiversity knowledge and to create useful data on backyard biodiversity worldwide towards human sustainability

    An Electron Fixed Target Experiment to Search for a New Vector Boson A' Decaying to e+e-

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    We describe an experiment to search for a new vector boson A' with weak coupling alpha' > 6 x 10^{-8} alpha to electrons (alpha=e^2/4pi) in the mass range 65 MeV < m_A' < 550 MeV. New vector bosons with such small couplings arise naturally from a small kinetic mixing of the "dark photon" A' with the photon -- one of the very few ways in which new forces can couple to the Standard Model -- and have received considerable attention as an explanation of various dark matter related anomalies. A' bosons are produced by radiation off an electron beam, and could appear as narrow resonances with small production cross-section in the trident e+e- spectrum. We summarize the experimental approach described in a proposal submitted to Jefferson Laboratory's PAC35, PR-10-009. This experiment, the A' Experiment (APEX), uses the electron beam of the Continuous Electron Beam Accelerator Facility at Jefferson Laboratory (CEBAF) at energies of ~1-4 GeV incident on 0.5-10% radiation length Tungsten wire mesh targets, and measures the resulting e+e- pairs to search for the A' using the High Resolution Spectrometer and the septum magnet in Hall A. With a ~1 month run, APEX will achieve very good sensitivity because the statistics of e+e- pairs will be ~10,000 times larger in the explored mass range than any previous search for the A' boson. These statistics and the excellent mass resolution of the spectrometers allow sensitivity to alpha'/alpha one to three orders of magnitude below current limits, in a region of parameter space of great theoretical and phenomenological interest. Similar experiments could also be performed at other facilities, such as the Mainz Microtron.Comment: 19 pages, 12 figures, 2 table

    Ablation of the renal stroma defines its critical role in nephron progenitor and vasculature patterning

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    The renal stroma is an embryonic cell population located in the cortex that provides a structural framework as well as a source of endothelial progenitors for the developing kidney. The exact role of the renal stroma in normal kidney development hasn't been clearly defined. However, previous studies have shown that the genetic deletion of Foxd1, a renal stroma specific gene, leads to severe kidney malformations confirming the importance of stroma in normal kidney development. This study further investigates the role of renal stroma by ablating Foxd1-derived stroma cells themselves and observing the response of the remaining cell populations. A Foxd1cre (renal stroma specific) mouse was crossed with a diphtheria toxin mouse (DTA) to specifically induce apoptosis in stromal cells. Histological examination of kidneys at embryonic day 13.5-18.5 showed a lack of stromal tissue, mispatterning of renal structures, and dysplastic and/or fused horseshoe kidneys. Immunofluorescence staining of nephron progenitors, vasculature, ureteric epithelium, differentiated nephron progenitors, and vascular supportive cells revealed that mutants had thickened nephron progenitor caps, cortical regions devoid of nephron progenitors, aberrant vessel patterning and thickening, ureteric branching defects and migration of differentiated nephron structures into the medulla. The similarities between the renal deformities caused by Foxd1 genetic knockout and Foxd1DTA mouse models reveal the importance of Foxd1 in mediating and maintaining the functional integrity of the renal stroma. © 2014 Hum et al

    The Endogenous Th17 Response in NO<inf>2</inf>-Promoted Allergic Airway Disease Is Dispensable for Airway Hyperresponsiveness and Distinct from Th17 Adoptive Transfer

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    Severe, glucocorticoid-resistant asthma comprises 5-7% of patients with asthma. IL-17 is a biomarker of severe asthma, and the adoptive transfer of Th17 cells in mice is sufficient to induce glucocorticoid-resistant allergic airway disease. Nitrogen dioxide (NO2) is an environmental toxin that correlates with asthma severity, exacerbation, and risk of adverse outcomes. Mice that are allergically sensitized to the antigen ovalbumin by exposure to NO2 exhibit a mixed Th2/Th17 adaptive immune response and eosinophil and neutrophil recruitment to the airway following antigen challenge, a phenotype reminiscent of severe clinical asthma. Because IL-1 receptor (IL-1R) signaling is critical in the generation of the Th17 response in vivo, we hypothesized that the IL-1R/Th17 axis contributes to pulmonary inflammation and airway hyperresponsiveness (AHR) in NO2-promoted allergic airway disease and manifests in glucocorticoid-resistant cytokine production. IL-17A neutralization at the time of antigen challenge or genetic deficiency in IL-1R resulted in decreased neutrophil recruitment to the airway following antigen challenge but did not protect against the development of AHR. Instead, IL-1R-/- mice developed exacerbated AHR compared to WT mice. Lung cells from NO2-allergically inflamed mice that were treated in vitro with dexamethasone (Dex) during antigen restimulation exhibited reduced Th17 cytokine production, whereas Th17 cytokine production by lung cells from recipient mice of in vitro Th17-polarized OTII T-cells was resistant to Dex. These results demonstrate that the IL-1R/Th17 axis does not contribute to AHR development in NO2-promoted allergic airway disease, that Th17 adoptive transfer does not necessarily reflect an endogenously-generated Th17 response, and that functions of Th17 responses are contingent on the experimental conditions in which they are generated. © 2013 Martin et al

    Giving Voice to School Nursing as a Primary Health Care Specialty

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    The purpose of this thesis is to give voice to school nursing as a primary health care specialty, and to promote the development of school nursing in New Zealand. School nursing is an invisible practice specialty that is largely funded from within the education sector, to address the health needs of student clients. School nursing is a significant primary health care initiative that can positively influence student health outcomes. My school nursing practice experience and philosophy is presented prior to reflecting upon the history of school nursing, and the health concerns present within the student population. The work then moves to review and critique school nursing literature from New Zealand, Australia, the United Kingdom, and the United States. This thesis highlights the need for collaborative policy and practice development initiatives including a legislative requirement for school nurses, school nursing competencies and standards, school nurse to student ratios, postgraduate training, professional liaison, practice funding, and research. A discourse on the reflective topical autobiographical method introduces autobiographical poetry from school nursing practice and reflective inquiry, as the central research endeavour of this thesis. Autobiographical poetry is offered as a window to this specialty practice, and accompanying reflections allow access to a further layer of practice knowledge. Student health needs, the scope of nursing intewentions, and the essences of school nursing practice have been distilled from the poetry. Poetic representation and subsequent reflection has facilitated the development of a school nursing framework for use within the New Zealand context, entitled Health Mediation in School Nursing. School nursing is presented throughout this thesis as an important child and adolescent primary health care initiative, which has the potential to reduce health barriers to learning, improve student health outcomes, and build student success in the social, emotional, and educational domains

    Giving Voice to School Nursing as a Primary Health Care Specialty

    No full text
    The purpose of this thesis is to give voice to school nursing as a primary health care specialty, and to promote the development of school nursing in New Zealand. School nursing is an invisible practice specialty that is largely funded from within the education sector, to address the health needs of student clients. School nursing is a significant primary health care initiative that can positively influence student health outcomes. My school nursing practice experience and philosophy is presented prior to reflecting upon the history of school nursing, and the health concerns present within the student population. The work then moves to review and critique school nursing literature from New Zealand, Australia, the United Kingdom, and the United States. This thesis highlights the need for collaborative policy and practice development initiatives including a legislative requirement for school nurses, school nursing competencies and standards, school nurse to student ratios, postgraduate training, professional liaison, practice funding, and research. A discourse on the reflective topical autobiographical method introduces autobiographical poetry from school nursing practice and reflective inquiry, as the central research endeavour of this thesis. Autobiographical poetry is offered as a window to this specialty practice, and accompanying reflections allow access to a further layer of practice knowledge. Student health needs, the scope of nursing intewentions, and the essences of school nursing practice have been distilled from the poetry. Poetic representation and subsequent reflection has facilitated the development of a school nursing framework for use within the New Zealand context, entitled Health Mediation in School Nursing. School nursing is presented throughout this thesis as an important child and adolescent primary health care initiative, which has the potential to reduce health barriers to learning, improve student health outcomes, and build student success in the social, emotional, and educational domains

    SEAGRID: A New Dynamic Modelling Tool for Power System Analysis of Ocean Energy Devices

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    International audienceAs the ocean energy industry approaches commercial readiness, there will be a greater focus on integration of ocean energy devices (OEDs) into the electrical power system network. Device developers will be required to provide dynamic models of their device for grid connection, and ensure their device operates within the limits laid out in the grid code. Project developers will need to assess the impact of different wavefarm configurations, ratings for the electrical equipment, power losses, and performance during a fault. Grid operators will require dynamic models to investigate the impact an OED will have on the grid and also for future grid planning studies. The SEAGRID dynamic modelling tool attempts to address each of these issues using its generic modelling approach. The SEAGRID model is capable of producing a scalable time domain power system dynamic model using empirical test data and component specifications, bypassing the need for a full hydrodynamic study of the device

    Electromagnetic Meson Production in the Nucleon Resonance Region

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    Recent experimental and theoretical advances in investigating electromagnetic meson production reactions in the nucleon resonance region are reviewed.Comment: 75 pages, 42 figure

    Combination of non-ionic and cationic surfactants in generating stable CO2 foam for enhanced oil recovery and carbon storage

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    Surfactant-stabilized CO2 foam is a promising technology to reduce CO2 mobility in geo logic CO2 storage and CO2 enhanced oil recovery processes. In this study, various combi nations of a non-ionic surfactant, Alkyl polyglycoside, along with cationic surfactants were ingeniously examined to enhance carbon storage and facilitate oil recovery through CO2 based foam flooding. Specifically, for the first time, the investigation focused on the impact of altering the alkyl chain length and counter-ion type of the cationic surfactants. The surfactant combinations were first screened based on surfactant characterization, surface and interfacial tension studies and bulk foam experiments. The interfacial tension studies showed that, in combination with Alkyl polyglycosides, the C16 (cetyltrimethylammonium bromide and cetyltrimethylammonium chloride) alkyl chain length cationic surfactants exhibited less interfacial tension values than the C12 (dodecyltrimethylammonium bromide and dodecyltrimethylammonium chloride) alkyl chain length cationic surfactant. The bulk foam experiments established that Alkyl polyglycosides/C16 combination showed higher foamability and foam stability than Alkyl polyglycosides/C12 combination. The bulk foam investigation showed that the optimized concentration of Alkyl polyglycosides/cationic surfactant was 0.3/0.15 wt%. The surfactant combinations screened from these studies were evaluated for EOR coreflooding experiments at 1250 psi and 60 °C. The incremental oil recovery obtained for baseline CO2 and Alkyl polyglycosides/cetyltrimethylammonium bromide foam flooding was 18.5% and 32.7%, respectively. The estimated carbon storage potential for baseline CO2 g and Alkyl polyglycosides/cetyltrimethylammonium bromide foam flooding was 11.9% and 23.7%, respectively. The combination of Alkyl polygly cosides cetyltrimethylammonium bromide surfactant was demonstrated as an effective solution for increased oil recovery and carbon storage.Document Type: Original articleCited as: Tripathi, R., Alcorn, Z. P., Graue, A., Kulkarni, S. D. Combination of non-ionic and cationic surfactants in generating stable CO2 foam for enhanced oil recovery and carbon storage. Advances in Geo-Energy Research, 2024, 13(1): 42-55. https://doi.org/10.46690/ager.2024.07.0
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