Investigation of the Influence of Dynamic Loads of Industrial Equipment on the Occurrence of Prolonged Yielding of their Foundation Soils

Abstract The parameters of oscillations of the foundations and structures of the dynamic equipment of the new production workshop located in the Kharkiv region were experimentally investigated. For this purpose, appropriate measurements of the amplitude of oscillations in the vertical and orthogonal horizontal directions were performed. To compare the parameters of the amplitudes of forced oscillations and determine the damping properties of the applied rubber spacers placed between the frame and the slides, as well as the quenching effect of the foundation massif, several measurements of oscillation parameters were performed at the locations mentioned above. The amplitude of oscillations of the vertical component of the vibration load on different sides of the rubber dampers was reduced by 2-3 times, the horizontal component was completely attenuated. It was also established that there was no transmission of vibrations to the foundations of the production workshop. The safety of the measured parameters of oscillations from the point of view of long significant unstabilized subsidence of the foundations, both equipment and building, was determined. Recommendations for monitoring are given from the point of view of the possible deterioration of the properties of the used rubber dampers over time.</jats:p

Reconstruction of Shallow Foundations Using Peracetic Silicate Solutions

Abstract The modern world is facing the acute issues of environmental pollution. Recently, they have begun to come out on top in the global relations and in the cooperation of various global business entities. The states allocate significant funds both for measures to prevent environmental pollution and to combat their consequences. The operating experience of many enterprises has shown that the issues of reconstruction of the foundations of existing buildings and structures are currently acute and urgent. One of the most effective types of soil consolidation is stabilizing with various binders, such as silication, bituminous grouting, tarring, cementation. As economic exploitation of soils intensively increases, various pollutants, both organic and nonorganic, affect them by deteriorating their composition, structure and properties. Different types of soils react differently to pollutants, some of them are more “sensitive” to them while others are less “sensitive”. Pollution and environmental deterioration of soils due to the uncontrolled accumulation of various industrial wastes in the soils are the main problems. In this regard, under current conditions, along with the elimination of sources of pollution, it is necessary to develop new methods and technologies to prevent pollution. Physiochemical methods can solve these problems.</jats:p

Presence, localization and morphology of TELOCYTES in developmental gonads of fishes

Telocytes are a new defined type of interstitial cells, considered as a stem cell, with very long and thin cytoplasmic extensions. They are present in the vertebrates, and may participate in tissue remodeling. In fish, during gonadal development, the events that culminate with the germinal epithelium formation are well known. However, the interstitial compartment remains poorly explored, although it may have a great contribution to the morpho-functional changes that occur in the gonad. As in other organisms, in fish, the interstitium consists especially of connective tissue elements. However, until now, there are no reports of the presence and the action of the telocytes in the connective tissue of gonads of fish. Thus, this study aimed to detect the presence, localization and morphology of telocytes during the gonadal development of several species of fish. The gonads were analyzed by light microscopy, transmission electron microscopy and immunohistochemistry for localization of CD34, Vimentin, and metalloproteinases. The presence of two proteins characteristics of mesenchymal cell was detected in cells of the gonads of all species. In addition, they presented a typical morphology of telocytes, showing cellular extensions. Gonadal telocytes also presented positive response to metalloproteinases. In mammals, telocytes can undergo de-differentiation contributing to the reorganization of the extracellular matrix. This role may be performed by the metalloproteinases detected here. The detection of Vimentin and CD34 in the same cellular type, associated with its morphological characteristics, allows us to conclude that some interstitial cells in Teleostei are considered telocytes, identical to the ones already described in mammals and other vertebrates.Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Department of Cell and Development Biology Institute of Biomedical Sciences Federal University of Alfenas (UNIFAL-MG)Department of Morphology Botucatu Biosciences Institute State University of São Paulo (UNESP)Aquaculture Center of UNESP (CAUNESP) State University of São Paulo (UNESP)Department of Morphology Botucatu Biosciences Institute State University of São Paulo (UNESP)Aquaculture Center of UNESP (CAUNESP) State University of São Paulo (UNESP)FAPESP: 2014/00868-3FAPESP: 2015/16358-7FAPESP: 2016/10352-

RIQUET PROBLEM FOR ONE MODEL EQUATION OF THE 4TH ORDER HYPERBOLIC TYPE

Integral operators that transform arbitrary functions into regular solutions of hyperbolic equations of the second and higher orders are applied to solving boundary value problems. In particular, the Riquet problem for the Euler–Poisson–Darboux equation of the 4th order is posed and solved.</jats:p

Genetic Variation at Chromosome 2q13 and Its Potential Influence on Endometriosis Susceptibility Through Effects on the IL-1 Family

Endometriosis is characterized by the growth of epithelial and stromal cells outside the uterine cavity. It has a complex etiology and affects ∼10% of reproductive age women. It is accompanied by a chronic inflammatory response with substantial evidence to indicate genetic susceptibility. The causal genes and their pathways leading to endometriosis, however, are still unknown. Recently, genomewide association studies on endometriosis identified 14 genomic risk loci in women of European and Japanese ancestry. It is becoming increasingly clear that these risk regions are intergenic and thus contribute to disease susceptibility through regulatory mechanisms, most likely mediated through regulation of genes within a restricted distance from the risk variants. One endometriosis risk locus has been detected at chromosome 2q13 within an inflammatory-rich region of gene transcripts and thus may play a role in the inflammation component of the disease. We carried out detailed analysis of the genomic region 250 kb on either side of sentinel SNP rs10167914 and identified 21 transcripts which contained 6 interleukin (IL)-1 family genes, 3 previously reported coding genes that have a relationship to inflammation, 4 novel coding, or pseudogenes, and 8 noncoding RNA transcripts. Through an extensive literature search, we examined the roles these genes and their resultant proteins play in endometriosis pathogenesis. The results suggest alteration in the expression the IL-1 family transcripts either alone or as a complex milieu could have a significant influence on endometriosis and should be prioritized for future study on the implications of inflammation on endometriotic lesions