303 research outputs found
On chains in -closed topological pospaces
We study chains in an -closed topological partially ordered space. We give
sufficient conditions for a maximal chain in an -closed topological
partially ordered space such that contains a maximal (minimal) element.
Also we give sufficient conditions for a linearly ordered topological partially
ordered space to be -closed. We prove that any -closed topological
semilattice contains a zero. We show that a linearly ordered -closed
topological semilattice is an -closed topological pospace and show that in
the general case this is not true. We construct an example an -closed
topological pospace with a non--closed maximal chain and give sufficient
conditions that a maximal chain of an -closed topological pospace is an
-closed topological pospace.Comment: We have rewritten and substantially expanded the manuscrip
On the equivalence between hierarchical segmentations and ultrametric watersheds
We study hierarchical segmentation in the framework of edge-weighted graphs.
We define ultrametric watersheds as topological watersheds null on the minima.
We prove that there exists a bijection between the set of ultrametric
watersheds and the set of hierarchical segmentations. We end this paper by
showing how to use the proposed framework in practice in the example of
constrained connectivity; in particular it allows to compute such a hierarchy
following a classical watershed-based morphological scheme, which provides an
efficient algorithm to compute the whole hierarchy.Comment: 19 pages, double-colum
Candidate Type II Quasars at 2 < z < 4.3 in the Sloan Digital Sky Survey III
At low redshifts, dust-obscured quasars often have strong yet narrow
permitted lines in the rest-frame optical and ultraviolet, excited by the
central active nucleus, earning the designation Type II quasars. We present a
sample of 145 candidate Type II quasars at redshifts between 2 and 4.3,
encompassing the epoch at which quasar activity peaked in the universe. These
objects, selected from the quasar sample of the Baryon Oscillation
Spectroscopic Survey of the Sloan Digital Sky Survey III, are characterized by
weak continuum in the rest-frame ultraviolet (typical continuum magnitude of i
\approx 22) and strong lines of CIV and Ly \alpha, with Full Width at Half
Maximum less than 2000 kms-1. The continuum magnitudes correspond to an
absolute magnitude of -23 or brighter at redshift 3, too bright to be due
exclusively to the host galaxies of these objects. Roughly one third of the
objects are detected in the shorter-wavelength bands of the WISE survey; the
spectral energy distributions (SEDs) of these objects appear to be intermediate
between classic Type I and Type II quasars seen at lower redshift. Five objects
are detected at rest frame 6\mu m by Spitzer, implying bolometric luminosities
of several times 10^46 erg s-1. We have obtained polarization measurements for
two objects; they are roughly 3% polarized. We suggest that these objects are
luminous quasars, with modest dust extinction (A_V ~ 0.5 mag), whose
ultraviolet continuum also includes a substantial scattering contribution.
Alternatively, the line of sight to the central engines of these objects may be
partially obscured by optically thick material.Comment: 26 pages, 13 figures, 10 tables, 4 machine readable tables. Accepted
for publication in MNRA
Stability and convergence in discrete convex monotone dynamical systems
We study the stable behaviour of discrete dynamical systems where the map is
convex and monotone with respect to the standard positive cone. The notion of
tangential stability for fixed points and periodic points is introduced, which
is weaker than Lyapunov stability. Among others we show that the set of
tangentially stable fixed points is isomorphic to a convex inf-semilattice, and
a criterion is given for the existence of a unique tangentially stable fixed
point. We also show that periods of tangentially stable periodic points are
orders of permutations on letters, where is the dimension of the
underlying space, and a sufficient condition for global convergence to periodic
orbits is presented.Comment: 36 pages, 1 fugur
Near Infrared Spectra and Intrinsic Luminosities of Candidate Type II Quasars at 2 < z < 3.4
We present JHK near-infrared (NIR) spectroscopy of 25 candidate Type II
quasars selected from the Sloan Digital Sky Survey, using Triplespec on the
Apache Point Observatory 3.5m telescope, FIRE at the Magellan/Baade 6.5m
telescope, and GNIRS on Gemini. At redshifts of 2 < z < 3.4, our NIR spectra
probe the rest-frame optical region of these targets, which were initially
selected to have strong lines of CIV and Ly alpha, with FWHM<2000 km/s from the
SDSS pipeline. We use the [OIII]5007 line shape as a model for the narrow line
region emission, and find that \halpha\ consistently requires a broad component
with FWHMs ranging from 1000 to 7500 km/s. Interestingly, the CIV lines also
require broad bases, but with considerably narrower widths of 1000 to 4500
km/s. Estimating the extinction using the Balmer decrement and also the
relationship in lower-z quasars between rest equivalent width and luminosity in
the [OIII] line, we find typical A_V values of 0-2 mag, which naturally explain
the attenuated CIV lines relative to Halpha. We propose that our targets are
moderately obscured quasars. We also describe one unusual object with three
distinct velocity peaks in its [OIII] spectrum.Comment: Accepted for publication in ApJ, 18 pages, 14 figure
On the flux phase conjecture at half-filling: an improved proof
We present a simplification of Lieb's proof of the flux phase conjecture for
interacting fermion systems -- such as the Hubbard model --, at half filling on
a general class of graphs. The main ingredient is a procedure which transforms
a class of fermionic Hamiltonians into reflection positive form. The method can
also be applied to other problems, which we briefly illustrate with two
examples concerning the model and an extended Falicov-Kimball model.Comment: 23 pages, Latex, uses epsf.sty to include 3 eps figures, to appear in
J. Stat. Phys., Dec. 199
Primary and malignant cholangiocytes undergo CD40 mediated Fas dependent Apoptosis, but are insensitive to direct activation with exogenous fas ligand
Introduction
Cholangiocarcinoma is a rare malignancy of the biliary tract, the incidence of which is rising, but the pathogenesis of which remains uncertain. No common genetic defects have been described but it is accepted that chronic inflammation is an important contributing factor. We have shown that primary human cholangiocyte and hepatocyte survival is tightly regulated via co-operative interactions between two tumour necrosis family (TNF) receptor family members; CD40 and Fas (CD95). Functional deficiency of CD154, the ligand for CD40, leads to a failure of clearance of biliary tract infections and a predisposition to cholangiocarcinoma implying a direct link between TNF receptor-mediated apoptosis and the development of cholangiocarcinoma.
Aims
To determine whether malignant cholangiocytes display defects in CD40 mediated apoptosis. By comparing CD40 and Fas-mediated apoptosis and intracellular signalling in primary human cholangiocytes and three cholangiocyte cell lines.
Results
Primary cholangiocytes and cholangiocyte cell lines were relatively insensitive to direct Fas-mediated killing with exogenous FasL when compared with Jurkat cells, which readily underwent Fas-mediated apoptosis, but were extremely sensitive to CD154 stimulation. The sensitivity of cells to CD40 activation was similar in magnitude in both primary and malignant cells and was STAT-3 and AP-1 dependent in both.
Conclusions
1) Both primary and malignant cholangiocytes are relatively resistant to Fas–mediated killing but show exquisite sensitivity to CD154, suggesting that the CD40 pathway is intact and fully functional in both primary and malignant cholangiocytes 2) The relative insensitivity of cholangiocytes to Fas activation demonstrates the importance of CD40 augmentation of Fas dependent death in these cells. Agonistic therapies which target CD40 and associated intracellular signalling pathways may be effective in promoting apoptosis of malignant cholangiocytes
On extending actions of groups
Problems of dense and closed extension of actions of compact transformation
groups are solved. The method developed in the paper is applied to problems of
extension of equivariant maps and of construction of equivariant
compactifications
Algebraic topological analysis of time-sequence of digital images
This paper introduces an algebraic framework for a topological analysis of time-varying 2D digital binary–valued images, each of them defined as 2D arrays of pixels. Our answer is based on an algebraic-topological coding, called AT–model, for a nD (n=2,3) digital binary-valued image I consisting simply in taking I together with an algebraic object depending on it. Considering AT–models for all the 2D digital images in a time sequence, it is possible to get an AT–model for the 3D digital image consisting in concatenating the successive 2D digital images in the sequence. If the frames are represented in a quadtree format, a similar positive result can be derived
Reusing integer homology information of binary digital images
In this paper, algorithms for computing integer (co)homology of a simplicial complex of any dimension are designed, extending the work done in [1,2,3]. For doing this, the homology of the object is encoded in an algebraic-topological format (that we call AM-model). Moreover, in the case of 3D binary digital images, having as input AM-models for the images I and J, we design fast algorithms for computing the integer homology of I ∪J, I ∩J and I ∖J
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