16,057 research outputs found
Automated software quality visualisation using fuzzy logic techniques
In the past decade there has been a concerted effort by the software industry to improve the quality of its products. This has led to the inception of various techniques with which to control and measure the process involved in software development. Methods like the Capability Maturity Model have introduced processes and strategies that require measurement in the form of software metrics. With the ever increasing number of software metrics being introduced by capability based processes, software development organisations are finding it more difficult to understand and interpret metric scores. This is particularly problematic for senior management and project managers where analysis of the actual data is not feasible. This paper proposes a method with which to visually represent metric scores so that managers can easily see how their organisation is performing relative to quality goals set for each type of metric. Acting primarily as a proof of concept and prototype, we suggest ways in which real customer needs can be translated into a feasible technical solution. The solution itself visualises metric scores in the form of a tree structure and utilises Fuzzy Logic techniques, XGMML, Web Services and the .NET Framework. Future work is proposed to extend the system from the prototype stage and to overcome a problem with the masking of poor scores
A Quasi-Global Presentation of TIROS III Radiation Data
The TIROS III meteorological satellite was equipped with a five-channel medium resolution radiometer to measure the reflected solar radiation as well as the infrared emission of the earth-atmosphere system in five different spectral regions (Reference 1). According to the initial design of this radiation experiment, one of the most useful applications of the infrared measurements was to be the derivation of day and nighttime cloudiness from Channel 2, which was sensitive within the atmospheric "window" region (8 to 12 microns). Several authors already have demonstrated and discussed the principal usefulness of these data for this particular purpose (References 2, 3, and 4). This present study was performed to investigate and demonstrate the utility of the TIROS radiation data for global synoptic analyses
Mesenchymal Stem Cell Spheroids Retain Osteogenic Phenotype Through α2β1 Signaling.
Unlabelled: The induction of mesenchymal stem cells (MSCs) toward the osteoblastic lineage using osteogenic supplements prior to implantation is one approach under examination to enhance their bone-forming potential. MSCs rapidly lose their induced phenotype upon removal of the soluble stimuli; however, their bone-forming potential can be sustained when provided with continued instruction via extracellular matrix (ECM) cues. In comparison with dissociated cells, MSC spheroids exhibit improved survival and secretion of trophic factors while maintaining their osteogenic potential. We hypothesized that entrapment of MSC spheroids formed from osteogenically induced cells would exhibit better preservation of their bone-forming potential than would dissociated cells from monolayer culture. Spheroids exhibited comparable osteogenic potential and increased proangiogenic potential with or without osteogenic preconditioning versus monolayer-cultured MSCs. Spheroids were then entrapped in collagen hydrogels, and the osteogenic stimulus was removed. In comparison with entrapped dissociated MSCs, spheroids exhibited significantly increased markers of osteogenic differentiation. The capacity of MSC spheroids to retain their osteogenic phenotype upon withdrawal of inductive cues was mediated by α2β1 integrin binding to cell-secreted ECM. These results demonstrate the capacity of spheroidal culture to sustain the mineral-producing phenotype of MSCs, thus enhancing their contribution toward bone formation and repair.SignificanceDespite the promise of mesenchymal stem cells (MSCs) for cell-based therapies for tissue repair and regeneration, there is little evidence that transplanted MSCs directly contribute to new bone formation, suggesting that induced cells rapidly lose their osteogenic phenotype or undergo apoptosis. In comparison with dissociated cells, MSC spheroids exhibit increased trophic factor secretion and improved cell survival. The loss of phenotype represents a significant clinical challenge for cell therapies, yet there is no evidence for whether MSC spheroids retain their osteogenic phenotype upon entrapment in a clinically relevant biomaterial. These findings demonstrate that MSC spheroids retain their osteogenic phenotype better than do dissociated MSCs, and this is due to integrin engagement with the cell-secreted extracellular matrix. These data provide evidence for a novel approach for potentiating the use of MSCs in bone repair
NRQCD results on the MILC extra coarse ensemble
We present preliminary results using NRQCD to describe heavy quarks on the
MILC 2+1 flavour dynamical extra coarse ensemble. We calculate the spectra of
low lying states in bottomonium to complement earlier results on the finer MILC
ensembles. We then exploit the coarseness of the lattices to calculate charm
propagators using NRQCD. These are used to examine the charmonium spectrum and
to calclate the mass of the using NRQCD. Finally we look breifly at the
and systems using the imporoved staggered formalism to describe the
light valence quarks.Comment: 6 pages, Talk presented at Lattice 2005 (Heavy Quarks), Dublin, 25-30
July 200
ASSESSING THE EFFECTIVENESS OF MPP AND TEA ADVERTISING AND PROMOTION EFFORTS IN THE JAPANESE MARKET FOR MEATS
An Inverse Almost Ideal Demand System is utilized to determine the effectiveness of Market Promotion Program (MPP) and Target Export Assistance (TEA) advertising and promotion expenditures in the Japanese market for meat. Using annual data, it is found that beef advertising and promotion has had a positive and significant effect on the demand for beef. There is insufficient evidence to conclude that pork and poultry advertising and promotion increased the demand for either commodity.Marketing,
The Upsilon spectrum and m_b from full lattice QCD
We show results for the Upsilon spectrum calculated in lattice QCD including
for the first time vacuum polarization effects for light u and d quarks as well
as s quarks. We use gluon field configurations generated by the MILC
collaboration. The calculations compare the results for a variety of u and d
quark masses, as well as making a comparison to quenched results (in which
quark vacuum polarisation is ignored) and results with only u and d quarks. The
b quarks in the Upsilon are treated in lattice Nonrelativistic QCD through NLO
in an expansion in the velocity of the b quark. We concentrate on accurate
results for orbital and radial splittings where we see clear agreement with
experiment once u, d and s quark vacuum polarisation effects are included. This
now allows a consistent determination of the parameters of QCD. We demonstrate
this consistency through the agreement of the Upsilon and B spectrum using the
same lattice bare b quark mass. A one-loop matching to continuum QCD gives a
value for the b quark mass in full lattice QCD for the first time. We obtain
m_b^{\bar{MS}}(m_b^{\bar{MS}}) = 4.4(3) GeV. We are able to give physical
results for the heavy quark potential parameters, r_0 = 0.469(7) fm and r_1 =
0.321(5) fm. Results for the fine structure in the spectrum and the Upsilon
leptonic width are also presented. We predict the Upsilon - eta_b splitting to
be 61(14) MeV, the Upsilon^{\prime} - eta_b^{\prime} splitting as 30(19) MeV
and the splitting between the h_b and the spin-average of the chi_b states to
be less than 6 MeV. Improvements to these calculations that will be made in the
near future are discussed.Comment: 24 pages, 19 figures. Version to be published. Minor changes made and
typographical errors corrected. Experimental leptonic widths updated in
section
Dynamic polarization of graphene by moving external charges: random phase approximation
We evaluate the stopping and image forces on a charged particle moving
parallel to a doped sheet of graphene by using the dielectric response
formalism for graphene's -electron bands in the random phase approximation
(RPA). The forces are presented as functions of the particle speed and the
particle distance for a broad range of charge-carrier densities in graphene. A
detailed comparison with the results from a kinetic equation model reveal the
importance of inter-band single-particle excitations in the RPA model for high
particle speeds. We also consider the effects of a finite gap between graphene
and a supporting substrate, as well as the effects of a finite damping rate
that is included through the use of Mermin's procedure. The damping rate is
estimated from a tentative comparison of the Mermin loss function with a HREELS
experiment. In the limit of low particle speeds, several analytical results are
obtained for the friction coefficient that show an intricate relationship
between the charge-carrier density, the damping rate, and the particle
distance, which may be relevant to surface processes and electrochemistry
involving graphene.Comment: 14 pages, 10 figures, accepted for publication in Phys. Rev.
Simulation and analysis of solenoidal ion sources
We present a detailed analysis and simulation of solenoidal, magnetically confined electron bombardment ion sources, aimed at molecular beam detection. The aim is to achieve high efficiency for singly ionized species while minimizing multiple ionization. Electron space charge plays a major role and we apply combined ray tracing and finite element simulations to determine the properties of a realistic geometry. The factors controlling electron injection and ion extraction are discussed. The results from simulations are benchmarked against experimental measurements on a prototype source
Detection of a Substantial Molecular Gas Reservoir in a brightest cluster galaxy at z = 1.7
We report the detection of CO(2-1) emission coincident with the brightest
cluster galaxy (BCG) of the high-redshift galaxy cluster SpARCS1049+56, with
the Redshift Search Receiver (RSR) on the Large Millimetre Telescope (LMT). We
confirm a spectroscopic redshift for the gas of z = 1.7091+/-0.0004, which is
consistent with the systemic redshift of the cluster galaxies of z = 1.709. The
line is well-fit by a single component Gaussian with a RSR resolution-corrected
FWHM of 569+/-63 km/s. We see no evidence for multiple velocity components in
the gas, as might be expected from the multiple image components seen in
near-infrared imaging with the Hubble Space Telescope. We measure the
integrated flux of the line to be 3.6+/-0.3 Jy km/s and, using alpha_CO = 0.8
Msun (K km s^-1 pc^2)^-1 we estimate a total molecular gas mass of
1.1+/-0.1x10^11 Msun and a M_H2/M_star ~ 0.4. This is the largest gas reservoir
detected in a BCG above z > 1 to date. Given the infrared-estimated star
formation rate of 860+/-130 Msun/yr, this corresponds to a gas depletion
timescale of ~0.1Gyr. We discuss several possible mechanisms for depositing
such a large gas reservoir to the cluster center -- e.g., a cooling flow, a
major galaxy-galaxy merger or the stripping of gas from several galaxies -- but
conclude that these LMT data are not sufficient to differentiate between them.Comment: accepted for publication in ApJ Letter
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