135 research outputs found

    Areas for improvement in community optometry:flashes and floaters take priority

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    The TRiaDS in Optometry study is funded by NHS Education for Scotland. This study was conducted as part of the TRiaDS programme of research. We would like to thank Rumana Newlands, Lesley Rousselet, Patricia Graham, Cynthia Fraser, the TRiaDS administrative team, Optometry Scotland and all participating optometrists.Peer reviewedPublisher PD

    Macular and serum carotenoid concentrations in patients with malabsorption syndromes

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    The carotenoids lutein and zeaxanthin are believed to protect the human macula by absorbing blue light and quenching free radicals. Intestinal malabsorption syndromes such as celiac and Crohn’s disease are known to cause deficiencies of lipid-soluble nutrients. We hypothesized that subjects with nutrient malabsorption syndromes will demonstrate lower carotenoid levels in the macula and blood, and that these lower levels may correlate with early-onset maculopathy. Resonance Raman spectrographic (RRS) measurements of macular carotenoid levels were collected from subjects with and without a history of malabsorption syndromes. Carotenoids were extracted from serum and analyzed by high performance liquid chromatography (HPLC). Subjects with malabsorption (n = 22) had 37% lower levels of macular carotenoids on average versus controls (n = 25, P < 0.001). Malabsorption was not associated with decreased serum carotenoid levels. Convincing signs of early maculopathy were not observed. We conclude that intestinal malabsorption results in lower macular carotenoid levels

    When should I take the part 1 MRCOphth examination?

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    Vitamin A deficiency in coeliac disease

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