Microwave induced synthesis of some fused thiazoloquinazoline derivatives under solvent free conditions using LiBr as a catalyst

Two rapid and efficient methods for the preparation off used thiazoloquinazoline derivatives by the reaction of chalcones with hydroxylamine, urea and hydrazine hydrate under solvent free condition and microwave exposure are reported. The aim of present work is to substitute toxic, dangerous, highly reactive chemicals with less reactive, less harmful but more selective building blocks which activate selective chemical reactions by proper catalysis and to replace substituted old technologies to new one characterized by the reduction of by-products and easy separation of products

A Lightweight Stemmer for Gujarati

Gujarati is a resource poor language with almost no language processing tools being available. In this paper we have shown an implementation of a rule based stemmer of Gujarati. We have shown the creation of rules for stemming and the richness in morphology that Gujarati possesses. We have also evaluated our results by verifying it with a human expert

Improving the quality of Gujarati-Hindi Machine Translation through part-of-speech tagging and stemmer-assisted transliteration

Machine Translation for Indian languages is an emerging research area. Transliteration is one such module that we design while designing a translation system. Transliteration means mapping of source language text into the target language. Simple mapping decreases the efficiency of overall translation system. We propose the use of stemming and part-of-speech tagging for transliteration. The effectiveness of translation can be improved if we use part-of-speech tagging and stemming assisted transliteration.We have shown that much of the content in Gujarati gets transliterated while being processed for translation to Hindi language

PENGARUH PROMOSI KESEHATAN PERILAKU HIDUP BERSIH DAN SEHAT (PHBS) PADA TATANAN SEKOLAH TERHADAP PENGETAHUAN PHBS SISWA KELAS IV DAN V DI SD NEGERI NGEMPLAK SURAKARTA

ABSTRAK Latar Belakang: Promosi kesehatan dapat meningkatkan pengetahuan, sikap dan perilaku, khususnya pengetahuan perilaku hidup bersih dan sehat. Penelitian ini bertujuan untuk membuktikan pengaruh promosi kesehatan terhadap pengetahuan perilaku hidup bersih dan sehat. Metode: Penelitian ini merupakan penelitian pre experimental design dengan rancangan one group pretes posttest design yang dilaksanakan pada 12 April 2013 di SD Negeri Ngemplak Surakarta. Populasi penelitian adalah semua siswa SD Negeri Ngemplak Surakarta yang berjumlah 230 orang. Sedangkan pengambilan sampel dilaksanakan secara simple random sampling pada siswa kelas IV dan V. Sampel terdiri dari 32 siswa kelas IV dan 38 siswa kelas V. Maka jumlah total sampel yaitu 70 siswa. Variabel bebas pada penelitian ini adalah promosi kesehatan perilaku hidup bersih dan sehat pada tatanan sekolah yang alat pengukurannya berupa slide dan poster. Sedangkan untuk variabel terikat yaitu pengetahuan perilaku hidup bersih dan sehat dengan alat ukur menggunakan kuesioner yang telah diuji validitas dan reliabilitasnya. Dianalisis menggunakan Uji Marginal Homogeneity melalui program SPSS 16.0 for Windows. Hasil: Penelitian ini menunjukkan (1) Pengetahuan meningkat setelah dilakukan promosi kesehatan perilaku hidup bersih dan sehat sejumlah 62 siswa atau 88,57% dari seluruh siswa yang hadir, siswa yang pengetahuannya menurun sebanyak 2 siswa atau 2,8% dan yang tetap 6 siswa atau 8,57% (2) hasil Uji Marginal Homogeneity menunjukkan p = 0,000. Simpulan: Terdapat pengaruh promosi kesehatan perilaku hidup bersih dan sehat pada tatanan sekolah terhadap peningkatan pengetahuan PHBS siswa kelas IV dan V di SD Negeri Ngemplak Surakarta. Siswa yang berpengetahuan baik setelah intervensi lebih banyak dibandingkan sebelumnya. Kata kunci : promosi kesehatan PHBS, pengetahuan PHBS ABSTRACT Background: Health promotion can improve knowledge, attitudes and behavior, particullary knowledge of Clean and Healthy Behavior. This study aims to prove the effect of health promotion on knowledge of Clean and Healthy Behavior. Methods: This research is a pre-experimental design with the plan of one-group pretest posttest design was held on 12 April 2013 at SD Negeri Ngemplak Surakarta. The study population was all students of SD Negeri Ngemplak Surakarta totaling 230 people. While the sampling carried out by simple random sampling in grade students IV and V. The sample consisted of 32 grade students IV and 38 grade students V. Then the total number of samples is 70 students. The independent variable in this study is a health promotion of clean and healthy behavior in the order of school a measurement tool slides and posters. As for the dependent variable is the knowledge of clean and healthy behavior are measured using a questionnaire that have been tested for validity and reliability. Analyzed using marginal homogeneity test through SPSS 16.0 for Windows program. Results : This research shows a increased knowledge after health promotion Clean and Healthy Behavior a number of 62 students or 88.57% of all students in attendance, knowledge of students decreased a number of 2 students or 2.8% and a fixed 6 students or 8.57 % and the marginal homogeneity test results showed p = 0.000. Conclusion:. There is the influence of health promotion of clean and healthy behavior in the order of school to knowledge clean and healthy behavior students in class IV and V SD Negeri Ngemplak Surakarta. Students who are knowledgeable well after the intervention more than ever before. Key words : health promotion of PHBS, knowledge PHB

Modeling of 2D and 3D Assemblies Taking Into Account Form Errors of Plane Surfaces

The tolerancing process links the virtual and the real worlds. From the former, tolerances define a variational geometrical language (geometric parameters). From the latter, there are values limiting those parameters. The beginning of a tolerancing process is in this duality. As high precision assemblies cannot be analyzed with the assumption that form errors are negligible, we propose to apply this process to assemblies with form errors through a new way of allowing to parameterize forms and solve their assemblies. The assembly process is calculated through a method of allowing to solve the 3D assemblies of pairs of surfaces having form errors using a static equilibrium. We have built a geometrical model based on the modal shapes of the ideal surface. We compute for the completely deterministic contact points between this pair of shapes according to a given assembly process. The solution gives an accurate evaluation of the assembly performance. Then we compare the results with or without taking into account the form errors. When we analyze a batch of assemblies, the problem is to compute for the nonconformity rate of a pilot production according to the functional requirements. We input probable errors of surfaces (position, orientation, and form) in our calculus and we evaluate the quality of the results compared with the functional requirements. The pilot production then can or cannot be validated

MW assisted synthesis of some heterocyclic compounds and their Mannich bases under solvent free conditions and their biological assay

A highly efficient MW assisted synthesis of different nitrogen containing heterocyclic compounds under solvent free conditions was reported. Their aminomethylation was carried out on acidic alumina under microwave irradiation to give the corresponding Mannich bases. The method is clean, fast, facile, efficient, low cost and environmentally benign. The structure of synthesized compounds has been characterized on the basis of their elemental analysis and spectral data. These compounds were evaluated for their antimicrobial activity against bacteria and fungi

Effect of humic acid and nutrients mixture on quality parameter of Tomato (Lycopersicon esculentum Mill.) under polyhouse condition

An experiment was conducted on Effect of humic acid and nutrients mixture on growth and yield parameter of Tomato (Lycopersicon esculentum Mill.) under polyhouse condition at Rajasthan College of Agriculture, Udaipur (Raj.). The data was analyzed statistically following completely randomized design. The results revealed that treatment T7 [(RDF + humic acid 10 kg/ha soil application + humic acid 0.1% foliar spray + nutrient mixture foliar spray (0.2% Ca + 0.5% Mg + 0.2% B + 0.5% Zn)] was recorded superior to enhance leaf nutrients analysis Ca (1.656%), Mg (0.763%), Zn (25.07ppm) and B (61.94ppm), fruit nutrient analysisCa (1.904%), Mg (0.877%), Zn (58.98ppm) and B (61.84ppm), total Soluble Solids (TSS) (6.020%), ascorbic acid content (39.85mg/100g), lycopene content (3.75 mg/100g) and cost benefit ratio (4.81)

Simultaneous quantification of Darunavir and Ritonavir in human plasma and pharmacokinetic study by LC MS/MS

285-296The combination of Darunavir (DRV) and Ritonavir (RTV) at a dose of 800/100mg has exhibit durable efficacy in both untreated and treated HIV positive patients with no observed DRV resistance-associated mutations (RAMs) and the RTV improves the pharmacokinetic profile of DRV by enhancing its bioavailability. Hence a sensitive high-performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS) method has been developed and validated for the simultaneous quantification of Darunavir (DRV) and Ritonavir (RTV) in human plasma. The chromatographic separation has been accomplished on Thermo Hypersil Gold (50×4.6mm, 3μ) analytical column using isocratic elution using 0.1% Formic Acid buffer solution/Acetonitrile (50:50, v/v) at a flow rate of 0.6 mL/min. The linearity of the method ranged 150.000 ng/mL to 15000.000 ng/mL & 10.000 ng/mL to 3000.00 ng/mL for DRV & RTV respectively, using 100 μL of plasma. The method was completely validated for its sensitivity, selectivity, linearity, accuracy and precision, recovery, matrix effect, stability, and dilution integrity. The absolute recovery for DRV ranged from 79.12 to 72.71 % while for RTV it ranged from 63.39% to 66.99 %. For DRV-D9 and RTV-D6 the recovery rates are 94.19 and 80.05% respectively. The method exhibit good intra-day and inter-day precision with low % CV of less than 5.0% at each quality control level for both the analytes. The developed method has been applied successfully for pharmacokinetic study in healthy humans by oral administration of Darunavir/Ritonavir tablets 400/50 mg (dose; 02x400/50 mg) in 77 healthy male volunteers under fed condition

Classification of HRS using SVM

The kidney diseases are one of the main causes of death around the world. Automatic detection and classification of kidney related diseases are important for diagnosis of kidney irregularities. Hepatorenal Syndrome (HRS) is a lifethreatening medical condition when kidney fails due to liver failure. The treatment to such cases is liver transplant, or dialysis for temporary basis. This paper proposed to apply the Support Vector Machine (SVM) classification for diagnosis of HRS. The results were evaluated using realistic data from hospitals. RBF kernel function is used along with SVM. The results show a significant accuracy of 95%