3 research outputs found
The Dichloroacetate Dilemma: Environmental Hazard versus Therapeutic Goldmine—Both or Neither?
Get PDFEtiology, Clinical Profile, Gender Identity and Long-Term Follow Up of Patients with Ambiguous Genitalia in India
No full textDichloroacetate inhibits aerobic glycolysis in multiple myeloma cells and increases sensitivity to bortezomib
No full textBackground: Dichloroacetate (DCA), through the inhibition of aerobic glycolysis (the 'Warburg effect') and promotion of pyruvate oxidation, induces growth reduction in many tumours and is now undergoing several clinical trials. If aerobic glycolysis is active in multiple myeloma (MM) cells, it can be potentially targeted by DCA to induce myeloma growth inhibition
