Effect of Stretching on Chronic Non-Specific Neck Pain and Pressure Pain Threshold: A Pilot RCT

Non-specific chronic neck pain commonly affects office workers. Previous studies have explored various forms of physical exercise as therapies to alleviate pain and improve function. However, limited research has investigated stretching as an isolated intervention among office workers, with only one study demonstrating promising results. This pilot study aimed to assess the effectiveness of a 4-week static stretching protocol as a standalone treatment for reducing self-reported pain levels and improving pressure pain threshold (PPT) in women experiencing chronic non-specific neck pain. Sixty-six employed women with moderate to severe chronic neck pain were randomly assigned to either the static stretching (SS) or control group (CG). The SS group performed six neck muscle stretching exercises regularly for 4 weeks. Therapeutic effectiveness was evaluated before treatment initiation and at the end of the 4-week treatment period using the 11-point numerical pain rating scale (NPRS) and pressure pain threshold (PPT). Significant findings revealed a decrease in PPT in favor of the SS group, indicating reduced pressure pain sensitivity (p=0.013). However, there was no significant difference in NPRS between the two groups at the 4-week assessment (p=0.798). Our findings suggest that static stretching leads to a decrease in PPT but does not influence NPRS in women with chronic non-specific neck pain. Further evaluation of static stretching in a larger population with non-specific chronic neck pain is warranted. Additionally, future studies should investigate the optimal training dosage required to induce physiological and neuromuscular changes potentially linked to decreased neck pain and increased PPT levels.13pubpub

Seawater carbonate chemistry and processes during experiments with marine mussel, Mytilus galloprovincialis, 2005

In the context of future scenarios of progressive accumulation of anthropogenic CO2 in marine surface waters, the present study addresses the effects of long-term hypercapnia on a Mediterranean bivalve, Mytilus galloprovincialis. Sea-water pH was lowered to a value of 7.3 by equilibration with elevated CO2 levels. This is close to the maximum pH drop expected in marine surface waters during atmosextracellular pHric CO2 accumulation. Intra- and extracellular acid-base parameters as well as changes in metabolic rate and growth were studied under both normocapnia and hypercapnia. Long-term hypercapnia caused a permanent reduction in haemolymph pH. To limit the degree of acidosis, mussels increased haemolymph bicarbonate levels, which are derived mainly from the dissolution of shell CaCO3. Intracellular pH in various tissues was at least partly compensated; no deviation from control values occurred during long-term measurements in whole soft-body tissues. The rate of oxygen consumption fell significantly, indicating a lower metabolic rate. In line with previous reports, a close correlation became evident between the reduction in extracellular pH and the reduction in metabolic rate of mussels during hypercapnia. Analysis of frequency histograms of growth rate revealed that hypercapnia caused a slowing of growth, possibly related to the reduction in metabolic rate and the dissolution of shell CaCO3 as a result of extracellular acidosis. In addition, increased nitrogen excretion by hypercapnic mussels indicates the net degradation of protein, thereby contributing to growth reduction. The results obtained in the present study strongly indicate that a reduction in sea-water pH to 7.3 may be fatal for the mussels. They also confirm previous observations that a reduction in sea-water pH below 7.5 is harmful for shelled molluscs